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Cost-Reduction Initiatives and Acquisition-Related Costs We have incurred significant costs in connection with our cost-reduction initiatives (several false false Description of cost-reduction initiatives associated with a comprehensive plan to integrate acquired operations, generate cost savings and capture synergies across the company; as well as costs incurred in connection with the Wyeth acquisition. These costs include (i) restructuring activities, including exit and disposal activities, the major types of costs associated with the plan activities and the accrual balance at the end of the period; (ii) integration costs, which represent external, incremental costs directly related to integrating acquired businesses; (iii) implementation costs, which represent external, incremental costs directly related to implementing cost-reduction initiatives prior to the Wyeth acquisition and primarily include expenditures related to system and process standardization and the expansion of shared services. Costs related to Pfizer's cost-reduction initiatives incurred after the Wyeth acquisition, other than additional depreciation-asset restructuring, are included in Restructuring charges and certain acquisition-related costs on the income statement; (iv) additional depreciation-asset restructuring, which represents the impact of changes in the estimated useful lives of assets involved in restructuring actions; and (v) transaction costs, representing external costs directly related to effecting the acquisition of Wyeth. No authoritative reference available. false false 1 2 false UnKnown UnKnown UnKnown false true