Nautilus Biotechnology, Inc.

Prospectus Supplement for Primary Offering

Notice of Effectiveness

Entry into a Material Definitive Agreement

Beneficial ownership report for a holder of more than 5% (Schedule 13D) (amendment)

Registration statement under Securities Act of 1933

Beneficial ownership report for a holder of more than 5% (Schedule 13D) (amendment)

Beneficial ownership report for a holder of more than 5% (Schedule 13D) (amendment)

General form for quarterly reports under Section 13 or 15(d)

Results of Operations and Financial Condition

Beneficial ownership report for a holder of more than 5% (Schedule 13D) (amendment)

Submission of Matters to a Vote of Security Holders

Beneficial ownership report for a holder of more than 5% (Schedule 13D) (amendment)

General form for quarterly reports under Section 13 or 15(d)

Results of Operations and Financial Condition

Annual Report Scanned (Paper)

Definitive Proxy Statement

Additional Information for Proxy Statement/ Votes

Beneficial ownership report for a holder of more than 5% (Schedule 13D) (amendment)

Annual report pursuant to Section 13 or 15(d)

Results of Operations and Financial Condition

Registration statement under Securities Act of 1933 to be offered to employees pursuant to certain plans

Other Events

General form for quarterly reports under Section 13 or 15(d)

Results of Operations and Financial Condition

General form for quarterly reports under Section 13 or 15(d)

Results of Operations and Financial Condition

Submission of Matters to a Vote of Security Holders

Notice of Delisting or Failure to Satisfy a Continued Listing Rule or Standard; Transfer of Listing

General form for quarterly reports under Section 13 or 15(d)

Results of Operations and Financial Condition

Annual Report Scanned (Paper)

Additional Information for Proxy Statement/ Votes

Definitive Proxy Statement

Annual report pursuant to Section 13 or 15(d)

Results of Operations and Financial Condition

Registration statement under Securities Act of 1933 to be offered to employees pursuant to certain plans

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers: Compensatory Arrangements of Certain Officers

General form for quarterly reports under Section 13 or 15(d)

Results of Operations and Financial Condition

General form for quarterly reports under Section 13 or 15(d)

2.02,9.01

5.07

General form for quarterly reports under Section 13 or 15(d)

2.02,9.01

Annual Report Scanned (Paper)

Definitive Proxy Statement

Additional Information for Proxy Statement/ Votes

Notice of Effectiveness

Prospectus Supplement for Primary Offering

Correspondence with the SEC

Letter from the SEC

Annual report pursuant to Section 13 or 15(d)

1.01,9.01

2.02,9.01

Registration statement under Securities Act of 1933 to be offered to employees pursuant to certain plans

Registration statement under Securities Act of 1933

8.01

Prospectus Supplement for Primary Offering

General form for quarterly reports under Section 13 or 15(d)

General form for quarterly reports under Section 13 or 15(d)

General form for quarterly reports under Section 13 or 15(d)

Annual Report Scanned (Paper)

Definitive Proxy Statement

Additional Information for Proxy Statement/ Votes

Annual report pursuant to Section 13 or 15(d)

Registration statement under Securities Act of 1933 to be offered to employees pursuant to certain plans

General form for quarterly reports under Section 13 or 15(d)

Prospectus Supplement for Primary Offering

Notice of Effectiveness

General form for quarterly reports under Section 13 or 15(d)

Prospectus Supplement for Primary Offering

Post-effective amendment to a registration statement

Prospectus Supplement for Primary Offering

General form for quarterly reports under Section 13 or 15(d)

Prospectus Supplement for Primary Offering

Additional Information for Proxy Statement/ Votes

Definitive Proxy Statement

Prospectus Supplement for Primary Offering

Notice of Effectiveness

Annual report pursuant to Section 13 or 15(d)

Registration statement under Securities Act of 1933 to be offered to employees pursuant to certain plans

General form for quarterly reports under Section 13 or 15(d)

Correspondence with the SEC

Letter from the SEC

Correspondence with the SEC

Correspondence with the SEC

Letter from the SEC

Correspondence with the SEC

Letter from the SEC

Correspondence with the SEC

Letter from the SEC

Draft registration statement (confidential submission)

Correspondence with the SEC

Correspondence with the SEC

Correspondence with the SEC

Letter from the SEC

NAZEM FARZAD

McIlwain Matthew S

Posard Matthew L.

Epperly Melissa B,

Akinsanya Karen

Andreessen Marc L; HOROWITZ BENJAMIN A; AH Bio Fund II, L.P.; AH Equity Partners LSV II, L.L.C.; AH Equity Partners Bio II, L.L.C.; Andreessen Horowitz LSV Fund II, L.P.

Murphy Matthew B.

Patel Sujal M

Patel Sujal M

Weld Gwen E

Sankar Subramanian

Mowry Anna

Mallick Parag

Suzuki Kentaro