Institutional HoldersBeta

Who holds a company, from every 13F filed for the quarter, one row per filer exactly as filed, against the latest share count the company reported.

Abivax S.A.

CIK 0001956827AAVXFABVX· quarter ending 2026-06-30

Shares outstanding

78,536,412

as of 2025-12-31 · 20-F cover page, filed 2026-03-23

Held by 13F filers

55,075,642

70.1% of shares outstanding

Holders

303

+49 vs 2026-03-31 · 92 new, 43 exited

Value

$7.2B

shares +9.3% vs prior quarter

Share classes (cover page of the 20-F filed 2026-03-23, as of 2025-12-31)

Class	Listed	Shares outstanding	Held by 13F filers	% of class	Holders	CUSIP
Common stock	ABVX · NASDAQ	78,536,412	55,075,642	70.1%	303	00370M103

Each class is compared with its own share count; classes are not added together. A class that is not exchange-listed cannot be held by 13F filers.

Securities (CUSIPs held in 13F this quarter)

tick to combine

Count	CUSIP	Class (as filers write it)	Holders	Shares held	Class shares	% of class	Value	Options	Mapped via
	00370M103	SPONSORED ADS	303	55,075,642	78,536,412	70.1%	$7.2B	38 call / 25 put	13DG	holders →

Totals combine the ticked CUSIPs and update as you tick: common-stock classes by default; preferreds, notes, warrants and depositary shares are listed but not counted. "holders →" shows a single CUSIP on its own. Bonds are held as a principal amount, not shares. Options positions are never counted as holdings. 1 further CUSIPs map to this company (mostly bonds) but no 13F filer held them this quarter.

Top holders (250 of 303 · 00370M103)

change vs 2026-03-31

#	Filer	Shares	% of class	Value	Change
1	TCG Crossover Management, LLC	6,007,834	7.65%	$800.6M	-473,251 (-7.3%)
2	Darwin Global Management, Ltd.	3,621,583	4.61%	$348.2M	+152,926 (+4.4%)
3	Helikon Investments Ltd	2,787,131	3.55%	$371.4M	+1,773,807 (+175.0%)
4	Vestal Point Capital, LP	2,349,443	2.99%	$313.1M	+849,443 (+56.6%)
5	Jupiter Topco LLC	1,913,933	2.44%	$255.1M	NEW
6	UBS Group AG	1,844,918	2.35%	$245.9M	-2,702,488 (-59.4%)
7	ADAR1 Capital Management, LLC	1,804,703	2.30%	$240.5M	+410,684 (+29.5%)
8	Caligan Partners LP	1,557,924	1.98%	$207.6M	+96,000 (+6.6%)
9	CITADEL ADVISORS LLC	1,438,352	1.83%	$191.7M	+894,014 (+164.2%)
10	MORGAN STANLEY	1,432,185	1.82%	$190.9M	-272,773 (-16.0%)
11	WESTFIELD CAPITAL MANAGEMENT CO LP	1,309,825	1.67%	$174.5M	-13,113 (-1.0%)
12	RA CAPITAL MANAGEMENT, L.P.	1,132,557	1.44%	$150.9M	NEW
13	NORGES BANK	1,100,000	1.40%	$146.6M	NEW
14	SUSQUEHANNA INTERNATIONAL GROUP, LLP	1,053,896	1.34%	$140.4M	+672,614 (+176.4%)
15	Logos Global Management LP	1,024,000	1.30%	$136.5M	+349,000 (+51.7%)
16	Octagon Capital Advisors LP	993,000	1.26%	$132.3M	+316,000 (+46.7%)
17	BANK OF AMERICA CORP /DE/	971,439	1.24%	$129.5M	+235,710 (+32.0%)
18	Eversept Partners, LP	913,880	1.16%	$121.8M	-20,543 (-2.2%)
19	GOLDMAN SACHS GROUP INC	792,712	1.01%	$105.6M	+443,915 (+127.3%)
20	Nationale-Nederlanden Powszechne Towarzystwo Emerytalne S.A.	765,332	0.97%	$102.0M	-583 (-0.1%)
21	Cormorant Asset Management, LP	675,000	0.86%	$90.0M	-85,000 (-11.2%)
22	Boxer Capital Management, LLC	605,000	0.77%	$80.6M	+405,000 (+202.5%)
23	Balyasny Asset Management L.P.	603,840	0.77%	$80.5M	+390,151 (+182.6%)
24	Siren, L.L.C.	576,000	0.73%	$76.8M	NEW
25	BlackRock, Inc.	574,061	0.73%	$76.5M	+146,726 (+34.3%)
26	BOOTHBAY FUND MANAGEMENT, LLC	563,367	0.72%	$75.1M	+90,406 (+19.1%)
27	ORBIMED ADVISORS LLC	546,522	0.70%	$72.8M	+80,822 (+17.4%)
28	Aberdeen Group plc	522,025	0.66%	$69.6M	+90,784 (+21.1%)
29	Saturn V Capital Management LP	518,865	0.66%	$69.1M	-23,831 (-4.4%)
30	Artia Global Partners LP	516,447	0.66%	$68.8M	-84,300 (-14.0%)
31	Ensign Peak Advisors, Inc	504,471	0.64%	$67.2M	-127,367 (-20.2%)
32	Pictet Asset Management Holding SA	492,068	0.63%	$65.6M	+388,523 (+375.2%)
33	First Turn Management, LLC	489,889	0.62%	$65.3M	+24,020 (+5.2%)
34	Holocene Advisors, LP	418,657	0.53%	$55.8M	+160,000 (+61.9%)
35	Vivo Capital, LLC	414,899	0.53%	$55.3M	+175,360 (+73.2%)
36	SUMMIT PARTNERS PUBLIC ASSET MANAGEMENT, LLC	410,000	0.52%	$54.6M	NEW
37	EVENTIDE ASSET MANAGEMENT, LLC	394,957	0.50%	$52.6M	+74,381 (+23.2%)
38	MPM BIOIMPACT LLC	336,347	0.43%	$44.8M	+229,079 (+213.6%)
39	Affinity Asset Advisors, LLC	330,000	0.42%	$44.0M	-75,000 (-18.5%)
40	Ikarian Capital, LLC	328,635	0.42%	$43.4M	+271,000 (+470.2%)
41	Melqart Asset Management (UK) Ltd	307,250	0.39%	$40.9M	NEW
42	Kite Lake Capital Management (UK) LLP	300,600	0.38%	$40.1M	+200,600 (+200.6%)
43	PRICE T ROWE ASSOCIATES INC /MD/	300,365	0.38%	$40.0M	-391,305 (-56.6%)
44	FRANKLIN RESOURCES INC	299,754	0.38%	$39.9M	-83,076 (-21.7%)
45	STEMPOINT CAPITAL LP	283,657	0.36%	$37.8M	-343,925 (-54.8%)
46	HRT FINANCIAL LP	270,612	0.34%	$36.1M	+225,241 (+496.4%)
47	Nantahala Capital Management, LLC	267,518	0.34%	$35.6M	+130,281 (+94.9%)
48	PRINCIPAL FINANCIAL GROUP INC	257,678	0.33%	$34.3M	-54,596 (-17.5%)
49	Two Seas Capital LP	244,590	0.31%	$32.6M	NEW
50	READYSTATE ASSET MANAGEMENT LP	241,530	0.31%	$32.2M	+39,508 (+19.6%)
51	MILLENNIUM MANAGEMENT LLC	233,740	0.30%	$31.1M	-372,252 (-61.4%)
52	Woodline Partners LP	226,966	0.29%	$30.2M	+1,074 (+0.5%)
53	Patient Square Capital LP	206,500	0.26%	$27.5M	+85,255 (+70.3%)
54	GREAT POINT PARTNERS LLC	204,314	0.26%	$27.2M	NEW
55	Western Standard LLC	200,000	0.25%	$26.7M	NEW
56	JENNISON ASSOCIATES LLC	196,524	0.25%	$26.2M	-14,010 (-6.7%)
57	FMR LLC	191,689	0.24%	$25.5M	-1,094,684 (-85.1%)
58	TUDOR INVESTMENT CORP ET AL	187,335	0.24%	$25.0M	+85,724 (+84.4%)
59	FINDELL CAPITAL MANAGEMENT LLC	185,000	0.24%	$24.7M	+80,000 (+76.2%)
60	SILVERARC CAPITAL MANAGEMENT, LLC	169,593	0.22%	$22.6M	-132,937 (-43.9%)
61	DIADEMA PARTNERS LP	163,644	0.21%	$21.6M	+87,700 (+115.5%)
62	Focus Partners Wealth	161,874	0.21%	$21.6M	NEW
63	Creek Drive Management Group LLC	157,500	0.20%	$21.0M	+2,500 (+1.6%)
64	NAN FUNG TRINITY (HK) LTD	142,083	0.18%	$18.9M	+13,143 (+10.2%)
65	APEIRON CAPITAL Ltd	130,600	0.17%	$17.4M	NEW
66	AMERIPRISE FINANCIAL INC	129,816	0.17%	$17.3M	+46,785 (+56.3%)
67	WELLINGTON MANAGEMENT GROUP LLP	123,289	0.16%	$16.4M	NEW
68	DG Capital Management, LLC	122,267	0.16%	$16.3M	NEW
69	FARALLON CAPITAL MANAGEMENT, L.L.C.	122,000	0.16%	$16.3M	+120,000 (+6000.0%)
70	HighVista Strategies LLC	113,031	0.14%	$15.1M	-223 (-0.2%)
71	Seven Fleet Capital Management LP	111,334	0.14%	$14.8M	+68,282 (+158.6%)
72	Erste Asset Management GmbH	110,000	0.14%	$10.6M	+60,000 (+120.0%)
73	Prosight Management, LP	107,394	0.14%	$14.3M	+2,394 (+2.3%)
74	Verition Fund Management LLC	105,791	0.13%	$14.1M	+79,843 (+307.7%)
75	TimesSquare Capital Management, LLC	101,092	0.13%	$13.5M	-8,091 (-7.4%)
76	WELLS FARGO & COMPANY/MN	98,077	0.12%	$13.1M	+95,181 (+3286.6%)
77	ACT CAPITAL MANAGEMENT, LLC	97,000	0.12%	$12.9M	+26,100 (+36.8%)
78	SEI INVESTMENTS CO	92,176	0.12%	$12.3M	-2,044 (-2.2%)
79	D. E. Shaw & Co., Inc.	90,357	0.12%	$12.0M	+39,807 (+78.7%)
80	SEVEN GRAND MANAGERS, LLC	90,000	0.11%	$12.0M	+40,000 (+80.0%)
81	TORONTO DOMINION BANK	88,331	0.11%	$11.8M	NEW
82	IMC-Chicago, LLC	87,392	0.11%	$11.6M	-18,751 (-17.7%)
83	ODDO BHF ASSET MANAGEMENT SAS	81,496	0.10%	$10.9M	—
84	Qube Research & Technologies Ltd	81,216	0.10%	$10.8M	NEW
85	LPL Financial LLC	78,999	0.10%	$10.5M	+3,633 (+4.8%)
86	ANDERA PARTNERS	78,125	0.10%	$10.4M	—
87	FEDERATED HERMES, INC.	77,900	0.10%	$10.4M	-30,300 (-28.0%)
88	Optiver Holding B.V.	76,368	0.10%	$10.2M	+71,830 (+1582.9%)
89	Apis Capital Advisors, LLC	74,000	0.09%	$9.9M	-54,800 (-42.5%)
90	PERCEPTIVE ADVISORS LLC	74,000	0.09%	$9.9M	-254,884 (-77.5%)
91	NWI MANAGEMENT LP	72,000	0.09%	$9.6M	NEW
92	Quinn Opportunity Partners LLC	66,045	0.08%	$8.8M	+50,045 (+312.8%)
93	Velan Capital Investment Management LP	65,630	0.08%	$8.7M	-11,370 (-14.8%)
94	SummitTX Capital, L.P.	65,216	0.08%	$8.7M	NEW
95	Alberta Investment Management Corp	65,000	0.08%	$8.7M	+20,000 (+44.4%)
96	ENVESTNET ASSET MANAGEMENT INC	63,354	0.08%	$8.4M	+4,145 (+7.0%)
97	JANE STREET GROUP, LLC	60,195	0.08%	$8.0M	-33,946 (-36.1%)
98	Atle Fund Management AB	58,170	0.07%	$7.8M	+26,580 (+84.1%)
99	SAMSARA BIOCAPITAL, LLC	55,095	0.07%	$7.3M	-1,486 (-2.6%)
100	Senator Investment Group LP	55,000	0.07%	$7.3M	NEW
101	Diametric Capital, LP	51,903	0.07%	$6.9M	+41,903 (+419.0%)
102	GEODE CAPITAL MANAGEMENT, LLC	51,868	0.07%	$6.9M	+556 (+1.1%)
103	Ghisallo Capital Management LLC	48,000	0.06%	$6.0M	NEW
104	BNP PARIBAS ASSET MANAGEMENT Holding S.A.	47,460	0.06%	$6.3M	-2,056 (-4.2%)
105	Exome Asset Management LLC	46,878	0.06%	$6.2M	NEW
106	ROYCE & ASSOCIATES LP	45,103	0.06%	$6.0M	NEW
107	Persistent Asset Partners Ltd	44,256	0.06%	$5.9M	+21,418 (+93.8%)
108	PFM Health Sciences, LP	43,264	0.06%	$5.8M	+16,600 (+62.3%)
109	PSquared Asset Management AG	41,200	0.05%	$5.5M	+25,000 (+154.3%)
110	Longaeva Partners L.P.	40,000	0.05%	$5.3M	NEW
111	MAVERICK CAPITAL LTD	40,000	0.05%	$5.3M	NEW
112	SYQUANT CAPITAL SAS	39,500	0.05%	$5.3M	-3,000 (-7.1%)
113	ALPINE ASSOCIATES MANAGEMENT INC.	38,500	0.05%	$5.1M	NEW
114	Knoll Capital Management, LLC	35,000	0.04%	$4.7M	NEW
115	CenterBook Partners LP	33,811	0.04%	$4.5M	+25,375 (+300.8%)
116	Walleye Capital LLC	31,632	0.04%	$4.2M	+23,038 (+268.1%)
117	ExodusPoint Capital Management, LP	31,209	0.04%	$4.2M	-109,053 (-77.7%)
118	LANDSCAPE CAPITAL MANAGEMENT, L.L.C.	30,353	0.04%	$4.0M	—
119	NOMURA ASSET MANAGEMENT INTERNATIONAL INC.	30,000	0.04%	$4.0M	NEW
120	GROUP ONE TRADING LLC	29,767	0.04%	$4.0M	-6,000 (-16.8%)
121	PICTON MAHONEY ASSET MANAGEMENT	27,712	0.04%	$3.7M	NEW
122	Marex Group Ltd	27,336	0.03%	$3.6M	NEW
123	Atika Capital Management LLC	27,000	0.03%	$3.6M	-1,800 (-6.3%)
124	ADAGE CAPITAL PARTNERS GP, L.L.C.	26,500	0.03%	$3.5M	-374,039 (-93.4%)
125	RTW INVESTMENTS, LP	26,400	0.03%	$3.5M	NEW
126	Quantinno Capital Management LP	25,437	0.03%	$3.4M	NEW
127	GUGGENHEIM CAPITAL LLC	24,583	0.03%	$3.3M	-491 (-2.0%)
128	K2 PRINCIPAL FUND, L.P.	24,403	0.03%	$3.3M	-29,338 (-54.6%)
129	Burkehill Global Management, LP	24,000	0.03%	$3.2M	NEW
130	Alyeska Investment Group, L.P.	23,940	0.03%	$3.2M	NEW
131	Russell Investments Group, Ltd.	22,970	0.03%	$3.1M	-42,303 (-64.8%)
132	MONIMUS CAPITAL MANAGEMENT, LP	21,644	0.03%	$2.9M	NEW
133	Rosalind Advisors, Inc.	20,869	0.03%	$2.8M	NEW
134	Diversify Advisory Services, LLC	20,817	0.03%	$2.7M	NEW
135	DIVERSIFY WEALTH MANAGEMENT, LLC	20,817	0.03%	$2.7M	+3,081 (+17.4%)
136	Beartown Capital Management, LLC	20,000	0.03%	$2.7M	NEW
137	Voleon Capital Management LP	19,715	0.03%	$2.6M	-54,011 (-73.3%)
138	KENNEDY CAPITAL MANAGEMENT LLC	19,200	0.02%	$2.6M	+10,443 (+119.3%)
139	Virtu Financial LLC	19,155	0.02%	$2.6M	+9,604 (+100.6%)
140	Resolute Capital Asset Partners LLC	17,500	0.02%	$2.3M	NEW
141	Atom Investors LP	17,379	0.02%	$2.3M	NEW
142	Birchview Capital, LP	17,000	0.02%	$2.3M	NEW
143	TD Asset Management Inc	16,948	0.02%	$2.3M	-48,600 (-74.1%)
144	Dorsey Wright & Associates	16,645	0.02%	$2.2M	-6,807 (-29.0%)
145	BNP PARIBAS FINANCIAL MARKETS	15,710	0.02%	$2.1M	-24,652 (-61.1%)
146	SIH Partners, LLLP	15,564	0.02%	$2.1M	NEW
147	LMR Partners LLP	15,357	0.02%	$2.0M	-61,195 (-79.9%)
148	Greenland Capital Management LP	15,000	0.02%	$2.0M	+10,000 (+200.0%)
149	SUMMIT SECURITIES GROUP LLC	14,000	0.02%	$1.9M	NEW
150	Rangeley Capital, LLC	13,000	0.02%	$1.7M	+9,000 (+225.0%)
151	OMERS ADMINISTRATION Corp	13,000	0.02%	$1.7M	NEW
152	ROYAL BANK OF CANADA	11,839	0.02%	$1.6M	-3,284 (-21.7%)
153	FORA Capital, LLC	11,758	0.01%	$1.6M	-1,428 (-10.8%)
154	CITIGROUP INC	10,061	0.01%	$1.3M	+8,332 (+481.9%)
155	GABELLI FUNDS LLC	10,000	0.01%	$1.3M	+2,550 (+34.2%)
156	AdvisorShares Investments LLC	9,766	0.01%	$1.3M	-2,036 (-17.3%)
157	MANUFACTURERS LIFE INSURANCE COMPANY, THE	9,630	0.01%	$1.3M	-28,965 (-75.0%)
158	LORD, ABBETT & CO. LLC	9,500	0.01%	$1.3M	-845,420 (-98.9%)
159	VOYA INVESTMENT MANAGEMENT LLC	9,295	0.01%	$1.2M	-9,205 (-49.8%)
160	HARVEY CAPITAL MANAGEMENT INC	9,280	0.01%	$1.2M	+4,980 (+115.8%)
161	China Universal Asset Management Co., Ltd.	9,225	0.01%	$1.2M	-3,678 (-28.5%)
162	IRIDIAN ASSET MANAGEMENT LLC/CT	9,165	0.01%	$1.2M	NEW
163	Schonfeld Strategic Advisors LLC	8,918	0.01%	$1.2M	-5,395 (-37.7%)
164	Cetera Investment Advisers	8,114	0.01%	$1.1M	+854 (+11.8%)
165	Crossmark Global Holdings, Inc.	7,909	0.01%	$1.1M	+3,832 (+94.0%)
166	Mariner, LLC	7,855	0.01%	$1.0M	-3,151 (-28.6%)
167	T3 Companies, LLC	7,815	0.01%	$1.0M	+2,115 (+37.1%)
168	STIFEL FINANCIAL CORP	7,703	0.01%	$1.0M	-3,074 (-28.5%)
169	FNY Investment Advisers, LLC	7,605	0.01%	$1.0M	+549 (+7.8%)
170	Walleye Trading LLC	6,790	0.01%	$905K	-2,979 (-30.5%)
171	Covestor Ltd	6,774	0.01%	$902K	+5,883 (+660.3%)
172	SBI Okasan Asset Management Co.Ltd.	6,500	0.01%	$625K	—
173	MARK ASSET MANAGEMENT LP	6,452	0.01%	$860K	NEW
174	Bellevue Group AG	6,397	0.01%	$852K	+5,349 (+510.4%)
175	TRUIST FINANCIAL CORP	6,194	0.01%	$825K	+327 (+5.6%)
176	Tower Research Capital LLC (TRC)	6,172	0.01%	$822K	+5,502 (+821.2%)
177	TWO SIGMA SECURITIES, LLC	6,070	0.01%	$809K	+2,134 (+54.2%)
178	MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd.	5,742	0.01%	$765K	+729 (+14.5%)
179	JPMORGAN CHASE & CO	5,717	0.01%	$550K	-629,349 (-99.1%)
180	Atria Investments, Inc	5,608	0.01%	$747K	-384 (-6.4%)
181	J. Goldman & Co LP	5,446	0.01%	$726K	-7,303 (-57.3%)
182	Jump Financial, LLC	5,424	0.01%	$723K	NEW
183	Cannon Global Investment Management, LLC	5,300	0.01%	$706K	-700 (-11.7%)
184	Sanctuary Advisors, LLC	5,300	0.01%	$706K	+3,053 (+135.9%)
185	ELEVATION POINT WEALTH PARTNERS, LLC	5,256	0.01%	$700K	-474 (-8.3%)
186	AlphaCentric Advisors LLC	5,141	0.01%	$685K	+1,717 (+50.1%)
187	Burns Matteson Capital Management, LLC	5,105	0.01%	$680K	-144 (-2.7%)
188	Point72 Asset Management, L.P.	5,028	0.01%	$670K	-632,708 (-99.2%)
189	BARCLAYS PLC	4,899	0.01%	$653K	-85,876 (-94.6%)
190	STATE STREET CORP	4,860	0.01%	$467K	-147 (-2.9%)
191	Jefferies Financial Group Inc.	4,771	0.01%	$636K	-5,382 (-53.0%)
192	Colonial River Investments, LLC	4,658	0.01%	$621K	+617 (+15.3%)
193	HIMENSION CAPITAL (SINGAPORE) PTE. LTD.	4,591	0.01%	$612K	-5,068 (-52.5%)
194	Centiva Capital, LP	4,512	0.01%	$601K	-52,638 (-92.1%)
195	OPPENHEIMER ASSET MANAGEMENT INC.	4,477	0.01%	$597K	-19 (-0.4%)
196	MML INVESTORS SERVICES, LLC	4,332	0.01%	$577K	NEW
197	PRELUDE CAPITAL MANAGEMENT, LLC	4,089	0.01%	$545K	+558 (+15.8%)
198	NOMURA HOLDINGS INC	3,900	0.00%	$520K	NEW
199	Clear Street Group Inc.	3,811	0.00%	$0	NEW
200	PNC Financial Services Group, Inc.	3,769	0.00%	$502K	+3 (+0.1%)
201	PANAGORA ASSET MANAGEMENT INC	3,653	0.00%	$487K	NEW
202	Vontobel Holding Ltd.	3,448	0.00%	$459K	NEW
203	NOMURA ASSET MANAGEMENT CO LTD	3,344	0.00%	$446K	NEW
204	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	3,321	0.00%	$443K	NEW
205	PERSONAL CFO SOLUTIONS, LLC	3,313	0.00%	$441K	+286 (+9.4%)
206	BANK OF HAWAII	3,281	0.00%	$437K	-264 (-7.4%)
207	GSA CAPITAL PARTNERS LLP	3,142	0.00%	$419K	+1,285 (+69.2%)
208	QP WEALTH MANAGEMENT, LLC	3,107	0.00%	$414K	NEW
209	Invesco Ltd.	3,058	0.00%	$408K	-123,362 (-97.6%)
210	Avior Wealth Management, LLC	3,037	0.00%	$405K	-203 (-6.3%)
211	Catalyst Funds Management Pty Ltd	3,000	0.00%	$400K	-2,000 (-40.0%)
212	Mirae Asset Global Investments Co., Ltd.	2,872	0.00%	$383K	NEW
213	HARVEST MANAGEMENT LLC	2,800	0.00%	$373K	NEW
214	Caprock Group, LLC	2,707	0.00%	$361K	NEW
215	Guardian Partners Inc.	2,700	0.00%	$360K	—
216	SmartHarvest Portfolios, LLC	2,613	0.00%	$348K	-83 (-3.1%)
217	BAMCO INC /NY/	2,500	0.00%	$333K	-3,000 (-54.5%)
218	Integrated Wealth Concepts LLC	2,492	0.00%	$332K	-103 (-4.0%)
219	SG Americas Securities, LLC	2,462	0.00%	$328K	-467 (-15.9%)
220	CLEAR WAVE WEALTH MANAGEMENT LLC	2,360	0.00%	$314K	+48 (+2.1%)
221	SECTORAL ASSET MANAGEMENT INC	2,340	0.00%	$312K	—
222	MIRABELLA FINANCIAL SERVICES LLP	2,337	0.00%	$311K	-1,919 (-45.1%)
223	HSBC HOLDINGS PLC	2,284	0.00%	$308K	-13,142 (-85.2%)
224	Merit Financial Group, LLC	2,255	0.00%	$301K	+18 (+0.8%)
225	RHUMBLINE ADVISERS	2,157	0.00%	$287K	+716 (+49.7%)
226	Engineers Gate Manager LP	2,133	0.00%	$284K	NEW
227	Pine Valley Investments Ltd Liability Co	2,025	0.00%	$270K	NEW
228	JONES FINANCIAL COMPANIES LLLP	2,014	0.00%	$196K	-2,056 (-50.5%)
229	HighTower Advisors, LLC	2,003	0.00%	$267K	NEW
230	GABELLI & Co INVESTMENT ADVISERS, INC.	2,000	0.00%	$267K	NEW
231	ProShare Advisors LLC	1,901	0.00%	$253K	-847 (-30.8%)
232	Nuveen, LLC	1,873	0.00%	$250K	NEW
233	PINNACLE ASSOCIATES LTD	1,864	0.00%	$248K	—
234	Pinnacle Wealth Management Advisory Group, LLC	1,864	0.00%	$248K	—
235	Total Clarity Wealth Management, Inc.	1,720	0.00%	$229K	-5,690 (-76.8%)
236	Moody Aldrich Partners LLC	1,667	0.00%	$222K	-591 (-26.2%)
237	Global Retirement Partners, LLC	1,605	0.00%	$214K	NEW
238	Allianz Asset Management GmbH	1,600	0.00%	$213K	-2,200 (-57.9%)
239	SIMPLEX TRADING, LLC	1,600	0.00%	$213K	-1,250 (-43.9%)
240	Goldstein Advisors, LLC	1,598	0.00%	$213K	NEW
241	RAYMOND JAMES FINANCIAL INC	1,572	0.00%	$209K	NEW
242	GF FUND MANAGEMENT CO. LTD.	1,302	0.00%	$174K	-24 (-1.8%)
243	Union Bancaire Privee, UBP SA	1,100	0.00%	$86K	+600 (+120.0%)
244	HANTZ FINANCIAL SERVICES, INC.	1,058	0.00%	$141K	-1,340 (-55.9%)
245	Troluce Capital Advisors LLC	1,000	0.00%	$133K	NEW
246	NINE MASTS CAPITAL Ltd	998	0.00%	$133K	-6,502 (-86.7%)
247	State of Wyoming	866	0.00%	$115K	NEW
248	Winthrop Capital Management, LLC	856	0.00%	$114K	NEW
249	ASSETMARK, INC	742	0.00%	$99K	-144 (-16.3%)
250	RFG Advisory, LLC	643	0.00%	$86K	NEW

Exited since 2026-03-31 (43 filers; largest 25 shown)

JANUS HENDERSON GROUP PLC	−878,829
BAKER BROS. ADVISORS LP	−875,796
Paradigm Biocapital Advisors LP	−772,473
Evergreen Quality Fund GP, Ltd.	−144,300
Hudson Bay Capital Management LP	−139,379
Sio Capital Management, LLC	−135,800
Squadron Capital Management LLC	−130,000
Nicholas Investment Partners, LP	−90,206
Davern Capital Partners, LP	−78,125
Militia Capital Management LLC	−51,000
Trexquant Investment LP	−48,749
Catalio Capital Management, LP	−47,193
Candriam S.C.A.	−36,061
Ally Bridge Group (NY) LLC	−33,712
CAXTON ASSOCIATES LLP	−24,750
Brummer Multi-Strategy AB	−22,428
Cinctive Capital Management LP	−20,055
SCHRODER INVESTMENT MANAGEMENT GROUP	−17,928
FIFTH LANE CAPITAL, LP	−15,858
BANQUE PICTET & CIE SA	−15,040
E Fund Management Co., Ltd.	−13,732
Progeny 3, Inc.	−12,240
Legato Capital Management LLC	−10,533
Avidity Partners Management LP	−10,000
Brevan Howard Capital Management LP	−9,500

Large holders from 13D/13G (latest per reporting person, last 2 years)

Filed when a holder crosses 5% or changes materially, so often more current than the quarter-end 13F. Percentages are the filer's own, against the share count they used.

Reporting person	Form	Filed	Event	Shares	% of class
Chen Yu	SCHEDULE 13G/A	2026-08-14	2026-06-30	6,007,834	7%
TCG Crossover Fund II, L.P.	SCHEDULE 13G/A	2026-08-14	2026-06-30	1,083,457	1.3%
TCG Crossover Fund I, L.P.	SCHEDULE 13G/A	2026-08-14	2026-06-30	4,924,377	5.7%
TCG Crossover GP II, LLC	SCHEDULE 13G/A	2026-08-14	2026-06-30	1,083,457	1.3%
TCG Crossover GP I, LLC	SCHEDULE 13G/A	2026-08-14	2026-06-30	4,924,377	5.7%
Ulys, L.L.C.	SCHEDULE 13G/A	2026-08-13	2026-06-30	35,572	0%
Raymond Debbane	SCHEDULE 13G/A	2026-08-13	2026-06-30	4,825,759	6%
Avicenna Life Sci Master GP LLC	SCHEDULE 13G/A	2026-08-13	2026-06-30	35,572	0%
Avicenna Life Sci Master Fund LP	SCHEDULE 13G/A	2026-08-13	2026-06-30	35,572	0%
Invus Global Management, LLC	SCHEDULE 13G/A	2026-08-13	2026-06-30	4,790,187	6%
Invus Public Equities Advisors, LLC	SCHEDULE 13G/A	2026-08-13	2026-06-30	4,790,187	6%
Invus Public Equities, L.P.	SCHEDULE 13G/A	2026-08-13	2026-06-30	4,790,187	6%
Siren, L.L.C.	SCHEDULE 13G/A	2026-08-13	2026-06-30	4,790,187	6%
Kinam Hong	SCHEDULE 13D/A	2026-07-06	2026-07-02	3,535,843	4.3%
Cedric Moreau	SCHEDULE 13D/A	2026-07-06	2026-07-02	3,535,843	4.3%
Antoine Papiernik	SCHEDULE 13D/A	2026-07-06	2026-07-02	3,535,843	4.3%
Joseph Anderson	SCHEDULE 13D/A	2026-07-06	2026-07-02	3,535,843	4.3%
Jacques Theurillat	SCHEDULE 13D/A	2026-07-06	2026-07-02	3,535,843	4.3%
Sofinnova Crossover I SLP	SCHEDULE 13D/A	2026-07-06	2026-07-02	3,535,843	4.3%
Sofinnova Partners SAS	SCHEDULE 13D/A	2026-07-06	2026-07-02	3,535,843	4.3%
Venrock Healthcare Capital Partners III, L.P.	SCHEDULE 13G/A	2025-11-14	2025-09-30	576,729	0.8%
Bong Y. Koh	SCHEDULE 13G/A	2025-11-14	2025-09-30	576,729	0.8%
Venrock Healthcare Capital Partners EG, L.P.	SCHEDULE 13G/A	2025-11-14	2025-09-30	576,729	0.8%
Nimish Shah	SCHEDULE 13G/A	2025-11-14	2025-09-30	576,729	0.8%
VHCP Co-Investment Holdings III, LLC	SCHEDULE 13G/A	2025-11-14	2025-09-30	576,729	0.8%
VHCP Management EG, LLC	SCHEDULE 13G/A	2025-11-14	2025-09-30	576,729	0.8%
VHCP Management III, LLC	SCHEDULE 13G/A	2025-11-14	2025-09-30	576,729	0.8%
Deep Track Biotechnology Master Fund, Ltd.	SCHEDULE 13G/A	2025-08-14	2025-06-30	3,480,144	4.78%
David Kroin	SCHEDULE 13G/A	2025-08-14	2025-06-30	3,480,144	4.78%
Deep Track Capital, LP	SCHEDULE 13G/A	2025-08-14	2025-06-30	3,480,144	4.78%

Source: SEC Form 13F-HR information tables for the quarter ending 2026-06-30 (filed within 45 days of quarter end; amendments applied; values normalised to dollars), the share count from the company's latest 10-K/10-Q XBRL cover page, and Schedule 13D/13G filings. Each row is a legal 13F filer as filed — related entities (e.g. Vanguard's advisers) are not merged. Retail brokerage accounts are not reported on 13F, so the remainder is mostly retail and insiders.