SAB Biotherapeutics, Inc.

Prospectus Supplement for Primary Offering

Beneficial ownership report for a passive holder of more than 5% (Schedule 13G) (amendment)

Beneficial ownership report for a passive holder of more than 5% (Schedule 13G) (amendment)

Beneficial ownership report for a passive holder of more than 5% (Schedule 13G) (amendment)

Beneficial ownership report for a passive holder of more than 5% (Schedule 13G) (amendment)

Beneficial ownership report for a passive holder of more than 5% (Schedule 13G) (amendment)

Beneficial ownership report for a passive holder of more than 5% (Schedule 13G) (amendment)

Beneficial ownership report for a passive holder of more than 5% (Schedule 13G)

Beneficial ownership report for a holder of more than 5% (Schedule 13D) (amendment)

General form for quarterly reports under Section 13 or 15(d)

Regulation FD Disclosure

Submission of Matters to a Vote of Security Holders

Beneficial ownership report for a passive holder of more than 5% (Schedule 13G) (amendment)

Beneficial ownership report for a passive holder of more than 5% (Schedule 13G)

Beneficial ownership report for a passive holder of more than 5% (Schedule 13G)

General form for quarterly reports under Section 13 or 15(d)

Entry into a Material Definitive Agreement

Beneficial ownership report for a passive holder of more than 5% (Schedule 13G)

Definitive Proxy Statement

Regulation FD Disclosure

Registration statement under Securities Act of 1933 to be offered to employees pursuant to certain plans

Beneficial ownership report for a holder of more than 5% (Schedule 13D) (amendment)

Entry into a Material Definitive Agreement

Prospectus Supplement for Primary Offering

Prospectus Supplement for Primary Offering

Beneficial ownership report for a holder of more than 5% (Schedule 13D) (amendment)

Regulation FD Disclosure

Annual report pursuant to Section 13 or 15(d)

Beneficial ownership report for a passive holder of more than 5% (Schedule 13G) (amendment)

Beneficial ownership report for a passive holder of more than 5% (Schedule 13G) (amendment)

Regulation FD Disclosure

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers: Compensatory Arrangements of Certain Officers

Notice of Effectiveness

Correspondence with the SEC

Letter from the SEC

Other Events

Registration statement under Securities Act of 1933

Registration statement under Securities Act of 1933 to be offered to employees pursuant to certain plans

General form for quarterly reports under Section 13 or 15(d)

Prospectus Supplement for Primary Offering

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers: Compensatory Arrangements of Certain Officers

Notice of Effectiveness

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers: Compensatory Arrangements of Certain Officers

Registration statement under Securities Act of 1933 (amendment)

Registration statement under Securities Act of 1933

Definitive Proxy Statement

Preliminary Proxy Statement

General form for quarterly reports under Section 13 or 15(d)

Rule 506(b) provides a "safer harbor" for a private offering

Entry into a Material Definitive Agreement

Submission of Matters to a Vote of Security Holders

Definitive Proxy Statement

General form for quarterly reports under Section 13 or 15(d)

Registration statement under Securities Act of 1933 to be offered to employees pursuant to certain plans

Annual report pursuant to Section 13 or 15(d)

Entry into a Material Definitive Agreement

Other Events

General form for quarterly reports under Section 13 or 15(d)

7.01,9.01

Registration statement under Securities Act of 1933 to be offered to employees pursuant to certain plans

General form for quarterly reports under Section 13 or 15(d)

5.02,7.01,9.01

5.07

5.02,7.01,9.01

Definitive Proxy Statement

8.01,9.01

General form for quarterly reports under Section 13 or 15(d)

Notification of late filing of Form 10-Q

Annual report pursuant to Section 13 or 15(d)

Registration statement under Securities Act of 1933 to be offered to employees pursuant to certain plans

Prospectus Supplement for Primary Offering

Definitive Proxy Statement

Preliminary Proxy Statement

Notice of Effectiveness

Correspondence with the SEC

Registration statement under Securities Act of 1933 (amendment)

Additional Information for Proxy Statement/ Votes

General form for quarterly reports under Section 13 or 15(d)

Letter from the SEC

Registration statement under Securities Act of 1933

Definitive Proxy Statement

Preliminary Proxy Statement

06b

Letter from the SEC

Correspondence with the SEC

Letter from the SEC

Correspondence with the SEC

Letter from the SEC

General form for quarterly reports under Section 13 or 15(d)

Notification of late filing of Form 10-Q

Definitive Proxy Statement

General form for quarterly reports under Section 13 or 15(d)

Correspondence with the SEC

Letter from the SEC

Correspondence with the SEC

Letter from the SEC

Annual report pursuant to Section 13 or 15(d) (amendment)

Annual report pursuant to Section 13 or 15(d) (amendment)

Annual report pursuant to Section 13 or 15(d)

Notification of late filing of Form 10-K

Correspondence with the SEC

Letter from the SEC

Definitive Proxy Statement

Correspondence with the SEC

Letter from the SEC

Correspondence with the SEC

Correspondence with the SEC

Correspondence with the SEC

Kropotova Alexandra

Kropotova Alexandra

Kropotova Alexandra

To Lucy