Institutional HoldersBeta

Who holds a company, from every 13F filed for the quarter, one row per filer exactly as filed, against the latest share count the company reported.

Sana Biotechnology, Inc.

CIK 0001770121SANA· quarter ending 2026-06-30

Shares outstanding

299,360,637

as of 2026-08-03 · 10-Q cover page, filed 2026-08-10

Held by 13F filers

184,795,813

61.7% of shares outstanding

Holders

212

+9 vs 2026-03-31 · 33 new, 24 exited

Value

$644.8M

shares +12.5% vs prior quarter

Share classes (cover page of the 10-Q filed 2026-08-10, as of 2026-08-03)

Class	Listed	Shares outstanding	Held by 13F filers	% of class	Holders	CUSIP
Common stock	SANA · NASDAQ	299,360,637	184,795,813	61.7%	212	799566104

Each class is compared with its own share count; classes are not added together. A class that is not exchange-listed cannot be held by 13F filers.

Securities (CUSIPs held in 13F this quarter)

tick to combine

Count	CUSIP	Class (as filers write it)	Holders	Shares held	Class shares	% of class	Value	Options	Mapped via
	799566104	COM	212	184,795,813	299,360,637	61.7%	$644.8M	4 call / 3 put	13DG	holders →

Totals combine the ticked CUSIPs and update as you tick: common-stock classes by default; preferreds, notes, warrants and depositary shares are listed but not counted. "holders →" shows a single CUSIP on its own. Bonds are held as a principal amount, not shares. Options positions are never counted as holdings.

Top holders (212 of 212 · 799566104)

change vs 2026-03-31

#	Filer	Shares	% of class	Value	Change
1	FMR LLC	37,429,515	12.50%	$130.6M	-769 (-0.0%)
2	Flagship Pioneering, LLC	25,001,856	8.35%	$87.3M	—
3	RA CAPITAL MANAGEMENT, L.P.	18,750,000	6.26%	$65.4M	NEW
4	BlackRock, Inc.	16,675,173	5.57%	$58.2M	+2,434,998 (+17.1%)
5	STATE STREET CORP	11,203,134	3.74%	$39.1M	+665,048 (+6.3%)
6	CANADA PENSION PLAN INVESTMENT BOARD	10,218,400	3.41%	$35.7M	-3,500 (-0.0%)
7	VANGUARD CAPITAL MANAGEMENT LLC	8,375,421	2.80%	$29.2M	+940,697 (+12.7%)
8	BANK OF AMERICA CORP /DE/	5,748,454	1.92%	$20.1M	+2,801,593 (+95.1%)
9	GEODE CAPITAL MANAGEMENT, LLC	4,677,959	1.56%	$16.3M	+495,986 (+11.9%)
10	Marex Group Ltd	3,989,100	1.33%	$13.9M	-10,000 (-0.3%)
11	MARSHALL WACE, LLP	2,931,436	0.98%	$10.2M	+2,266,979 (+341.2%)
12	Alphabet Inc.	2,812,500	0.94%	$9.8M	—
13	GOLDMAN SACHS GROUP INC	2,367,935	0.79%	$8.3M	-813,180 (-25.6%)
14	Integral Health Asset Management, LLC	2,000,000	0.67%	$7.0M	-1,200,000 (-37.5%)
15	TORONTO DOMINION BANK	1,972,381	0.66%	$6.9M	NEW
16	VANGUARD PORTFOLIO MANAGEMENT LLC	1,881,689	0.63%	$6.6M	+174,168 (+10.2%)
17	JACOBS LEVY EQUITY MANAGEMENT, INC	1,868,718	0.62%	$6.5M	NEW
18	NORTHERN TRUST CORP	1,604,084	0.54%	$5.6M	+125,233 (+8.5%)
19	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	1,379,181	0.46%	$4.8M	+13,033 (+1.0%)
20	Woodline Partners LP	1,317,932	0.44%	$4.6M	—
21	VANGUARD FIDUCIARY TRUST CO	1,237,437	0.41%	$4.3M	+173,788 (+16.3%)
22	RENAISSANCE TECHNOLOGIES LLC	1,231,100	0.41%	$4.3M	-220,100 (-15.2%)
23	MORGAN STANLEY	1,139,782	0.38%	$4.0M	-320,233 (-21.9%)
24	UBS Group AG	1,061,441	0.35%	$3.7M	-293,848 (-21.7%)
25	AQR CAPITAL MANAGEMENT LLC	963,147	0.32%	$3.4M	-161,132 (-14.3%)
26	Omega Fund Management, LLC	843,750	0.28%	$2.9M	—
27	JPMORGAN CHASE & CO	777,298	0.26%	$2.7M	-8,536 (-1.1%)
28	Crestline Management, L.P.	755,736	0.25%	$2.6M	—
29	ArrowMark Colorado Holdings LLC	685,125	0.23%	$2.4M	—
30	MILLENNIUM MANAGEMENT LLC	653,503	0.22%	$2.3M	-937,527 (-58.9%)
31	DEUTSCHE BANK AG\	645,087	0.22%	$2.3M	+53,176 (+9.0%)
32	TWO SIGMA INVESTMENTS, LP	638,837	0.21%	$2.2M	-559,742 (-46.7%)
33	Corient Private Wealth LP	628,100	0.21%	$2.2M	-14,000 (-2.2%)
34	Point72 Asset Management, L.P.	595,091	0.20%	$2.1M	NEW
35	Invesco Ltd.	504,262	0.17%	$1.8M	-64,924 (-11.4%)
36	Bank of New York Mellon Corp	477,542	0.16%	$1.7M	+34,938 (+7.9%)
37	SUSQUEHANNA INTERNATIONAL GROUP, LLP	384,083	0.13%	$1.3M	-37,472 (-8.9%)
38	Nuveen, LLC	369,722	0.12%	$1.3M	+42,750 (+13.1%)
39	Swiss National Bank	348,100	0.12%	$1.2M	+5,500 (+1.6%)
40	BAKER BROS. ADVISORS LP	310,483	0.10%	$1.1M	—
41	DIMENSIONAL FUND ADVISORS LP	294,842	0.10%	$1.0M	+3,574 (+1.2%)
42	UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC	284,472	0.10%	$993K	+52,766 (+22.8%)
43	PRICE T ROWE ASSOCIATES INC /MD/	282,916	0.09%	$988K	+75,424 (+36.4%)
44	CITIGROUP INC	272,524	0.09%	$951K	+212,133 (+351.3%)
45	XTX Topco Ltd	226,590	0.08%	$791K	+116,280 (+105.4%)
46	RHUMBLINE ADVISERS	223,412	0.07%	$780K	+24,716 (+12.4%)
47	Rafferty Asset Management, LLC	196,731	0.07%	$687K	-156,851 (-44.4%)
48	LOS ANGELES CAPITAL MANAGEMENT LLC	193,283	0.06%	$675K	+118,456 (+158.3%)
49	ALLIANCEBERNSTEIN L.P.	186,945	0.06%	$538K	—
50	CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM	181,749	0.06%	$634K	+18,190 (+11.1%)
51	Russell Investments Group, Ltd.	174,787	0.06%	$610K	+163,721 (+1479.5%)
52	WELLS FARGO & COMPANY/MN	173,546	0.06%	$606K	+97,864 (+129.3%)
53	Clearstead Advisors, LLC	170,739	0.06%	$596K	-166,042 (-49.3%)
54	ALGERT GLOBAL LLC	168,569	0.06%	$588K	-52,300 (-23.7%)
55	CITADEL ADVISORS LLC	161,178	0.05%	$563K	-407,912 (-71.7%)
56	Sound Capital Solutions LLC	140,217	0.05%	$489K	NEW
57	OPTIMIZE FINANCIAL INC.	140,217	0.05%	$489K	-488 (-0.3%)
58	Legal & General Group Plc	136,181	0.05%	$475K	+9,764 (+7.7%)
59	IEQ CAPITAL, LLC	128,792	0.04%	$449K	-58,935 (-31.4%)
60	Virtus Investment Advisers, LLC	122,089	0.04%	$426K	+69,037 (+130.1%)
61	GROUP ONE TRADING LLC	120,345	0.04%	$420K	+8,428 (+7.5%)
62	AMERIPRISE FINANCIAL INC	120,274	0.04%	$420K	NEW
63	Banque Cantonale Vaudoise	114,000	0.04%	$398K	+23,302 (+25.7%)
64	HSBC HOLDINGS PLC	111,959	0.04%	$392K	+39,765 (+55.1%)
65	MetLife Investment Management, LLC	109,959	0.04%	$384K	+43,408 (+65.2%)
66	ARROWSTREET CAPITAL, LIMITED PARTNERSHIP	109,597	0.04%	$382K	NEW
67	MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd.	107,424	0.04%	$374K	-36,086 (-25.1%)
68	VIRGINIA RETIREMENT SYSTEMS ET Al	102,850	0.03%	$359K	+11,000 (+12.0%)
69	VANGUARD ASSET MANAGEMENT, Ltd	101,668	0.03%	$355K	—
70	PROFUND ADVISORS LLC	99,502	0.03%	$347K	-57,620 (-36.7%)
71	VOYA INVESTMENT MANAGEMENT LLC	95,248	0.03%	$332K	-86,346 (-47.5%)
72	SG Americas Securities, LLC	95,039	0.03%	$332K	-35,044 (-26.9%)
73	GILDER GAGNON HOWE & CO LLC	89,960	0.03%	$314K	-5,836 (-6.1%)
74	TUDOR INVESTMENT CORP ET AL	87,892	0.03%	$307K	-45,291 (-34.0%)
75	Zurcher Kantonalbank (Zurich Cantonalbank)	82,393	0.03%	$288K	—
76	MANUFACTURERS LIFE INSURANCE COMPANY, THE	82,052	0.03%	$286K	+2,515 (+3.2%)
77	SCS Capital Management LLC	81,250	0.03%	$284K	—
78	VARCOV Co.	79,895	0.03%	$279K	NEW
79	Quadrature Capital Ltd	77,056	0.03%	$269K	+63,052 (+450.2%)
80	STATE OF WISCONSIN INVESTMENT BOARD	72,241	0.02%	$252K	-27,017 (-27.2%)
81	DRW Securities, LLC	66,249	0.02%	$231K	+53,866 (+435.0%)
82	WEALTH ENHANCEMENT ADVISORY SERVICES, LLC	61,827	0.02%	$238K	-209 (-0.3%)
83	Creative Planning	60,648	0.02%	$212K	-1,088 (-1.8%)
84	Vanguard Global Advisers, LLC	60,325	0.02%	$211K	—
85	Quinn Opportunity Partners LLC	60,100	0.02%	$210K	—
86	Palumbo Wealth Management LLC	59,773	0.02%	$209K	+1,314 (+2.2%)
87	Arax Advisory Partners	59,558	0.02%	$208K	+37,444 (+169.3%)
88	BNP PARIBAS FINANCIAL MARKETS	59,450	0.02%	$207K	+2,332 (+4.1%)
89	Jupiter Topco LLC	58,189	0.02%	$202K	NEW
90	Police & Firemen's Retirement System of New Jersey	57,903	0.02%	$202K	+13,658 (+30.9%)
91	State of New Jersey Common Pension Fund D	56,088	0.02%	$196K	-3,083 (-5.2%)
92	Brevan Howard Capital Management LP	52,545	0.02%	$183K	-265 (-0.5%)
93	BFSG, LLC	51,000	0.02%	$178K	—
94	BARCLAYS PLC	49,357	0.02%	$172K	+17,777 (+56.3%)
95	ARIZONA STATE RETIREMENT SYSTEM	47,864	0.02%	$167K	+307 (+0.6%)
96	INTECH INVESTMENT MANAGEMENT LLC	47,161	0.02%	$165K	+5,247 (+12.5%)
97	Cambridge Investment Research Advisors, Inc.	45,188	0.02%	$158K	+25,594 (+130.6%)
98	COLDSTREAM CAPITAL MANAGEMENT INC	45,000	0.02%	$157K	-1 (-0.0%)
99	China Universal Asset Management Co., Ltd.	44,290	0.01%	$155K	-2,979 (-6.3%)
100	Focus Partners Wealth	41,555	0.01%	$145K	-2,139 (-4.9%)
101	D. E. Shaw & Co., Inc.	40,090	0.01%	$140K	+1,420 (+3.7%)
102	NEW YORK STATE COMMON RETIREMENT FUND	38,609	0.01%	$135K	—
103	OP Asset Management Ltd	37,987	0.01%	$133K	NEW
104	AXQ CAPITAL, LP	37,771	0.01%	$132K	-19,140 (-33.6%)
105	Vanguard Investments Australia, Ltd.	37,523	0.01%	$131K	—
106	MAI Capital Management	37,303	0.01%	$130K	+36,611 (+5290.6%)
107	KLP KAPITALFORVALTNING AS	36,200	0.01%	$126K	—
108	Jain Global LLC	33,822	0.01%	$118K	NEW
109	ProShare Advisors LLC	33,172	0.01%	$116K	-3,084 (-8.5%)
110	Pictet Asset Management Holding SA	32,132	0.01%	$112K	—
111	LPL Financial LLC	31,533	0.01%	$110K	+11,721 (+59.2%)
112	Pallas Capital Advisors LLC	30,221	0.01%	$105K	-9,024 (-23.0%)
113	PRUDENTIAL FINANCIAL INC	29,785	0.01%	$104K	+4,520 (+17.9%)
114	GSA CAPITAL PARTNERS LLP	29,239	0.01%	$102K	-54,781 (-65.2%)
115	WINTON GROUP Ltd	28,400	0.01%	$99K	NEW
116	BLAIR WILLIAM & CO/IL	28,263	0.01%	$99K	+835 (+3.0%)
117	E Fund Management Co., Ltd.	27,740	0.01%	$97K	-16,706 (-37.6%)
118	STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM	26,678	0.01%	$93K	—
119	Cetera Investment Advisers	26,383	0.01%	$92K	+202 (+0.8%)
120	Squarepoint Ops LLC	24,523	0.01%	$86K	-93,952 (-79.3%)
121	NewEdge Advisors, LLC	24,370	0.01%	$85K	-23,050 (-48.6%)
122	Viewpoint Capital Management LLC	23,545	0.01%	$82K	—
123	Vanguard Personalized Indexing Management, LLC	22,654	0.01%	$79K	+1,022 (+4.7%)
124	HOEY INVESTMENTS, INC	22,000	0.01%	$77K	—
125	LaSalle St. Investment Advisors, LLC	22,000	0.01%	$77K	—
126	Cerity Partners LLC	21,336	0.01%	$74K	-18,847 (-46.9%)
127	TEACHER RETIREMENT SYSTEM OF TEXAS	20,254	0.01%	$71K	-2,238 (-10.0%)
128	VICTORY CAPITAL MANAGEMENT INC	20,085	0.01%	$70K	+1,063 (+5.6%)
129	Prodigy Asset Management LLC	20,050	0.01%	$70K	—
130	ALLSTATE CORP	19,628	0.01%	$69K	NEW
131	SYON CAPITAL LLC	18,501	0.01%	$65K	+1,838 (+11.0%)
132	OSAIC HOLDINGS, INC.	18,122	0.01%	$63K	-5,650 (-23.8%)
133	SEI INVESTMENTS CO	17,668	0.01%	$62K	—
134	XPONANCE LLC	17,631	0.01%	$62K	+2,551 (+16.9%)
135	Ameritas Investment Partners, Inc.	16,668	0.01%	$58K	+3,257 (+24.3%)
136	RAYMOND JAMES FINANCIAL INC	16,407	0.01%	$57K	-20,000 (-54.9%)
137	Quantinno Capital Management LP	16,083	0.01%	$56K	-2,950 (-15.5%)
138	Trace Wealth Advisors, LLC	16,000	0.01%	$56K	—
139	CAPTRUST FINANCIAL ADVISORS	15,713	0.01%	$55K	-130 (-0.8%)
140	Sequoia Financial Advisors, LLC	15,552	0.01%	$54K	NEW
141	Freestone Capital Holdings, LLC	15,100	0.01%	$53K	-200 (-1.3%)
142	Leonteq Securities AG	15,000	0.01%	$52K	—
143	GRIFFIN ASSET MANAGEMENT, INC.	14,620	0.00%	$51K	—
144	Merit Financial Group, LLC	14,488	0.00%	$51K	-11,570 (-44.4%)
145	Arkadios Wealth Advisors	14,407	0.00%	$50K	NEW
146	Swiss Life Asset Management Ltd	14,391	0.00%	$50K	+1,555 (+12.1%)
147	LANARK FINANCIAL, INC.	14,373	0.00%	$50K	+5,333 (+59.0%)
148	PRINCIPAL FINANCIAL GROUP INC	14,046	0.00%	$49K	NEW
149	Savant Capital, LLC	13,666	0.00%	$44K	NEW
150	PNC Financial Services Group, Inc.	13,052	0.00%	$46K	+1,009 (+8.4%)
151	Mirae Asset Global Investments Co., Ltd.	12,446	0.00%	$43K	-1,448 (-10.4%)
152	MERCER GLOBAL ADVISORS INC /ADV	12,379	0.00%	$43K	-265 (-2.1%)
153	MQS Management LLC	12,358	0.00%	$43K	NEW
154	Callan Family Office, LLC	12,224	0.00%	$43K	—
155	NEUBERGER BERMAN GROUP LLC	12,066	0.00%	$42K	-2,261 (-15.8%)
156	Centiva Capital, LP	11,874	0.00%	$41K	NEW
157	Bay Colony Advisory Group, Inc d/b/a Bay Colony Advisors	11,500	0.00%	$40K	-4,250 (-27.0%)
158	T3 Companies, LLC	11,300	0.00%	$39K	-22,500 (-66.6%)
159	Rockefeller Capital Management L.P.	11,065	0.00%	$39K	-2,700 (-19.6%)
160	Foguth Wealth Management, LLC.	10,981	0.00%	$34K	+150 (+1.4%)
161	NISA INVESTMENT ADVISORS, LLC	10,731	0.00%	$37K	+630 (+6.2%)
162	LYELL WEALTH MANAGEMENT, LP	10,500	0.00%	$37K	—
163	CIBC Bancorp USA Inc.	10,140	0.00%	$35K	NEW
164	LRI Investments, LLC	10,000	0.00%	$35K	—
165	TD Waterhouse Canada Inc.	10,000	0.00%	$36K	—
166	Jacobi Capital Management LLC	10,000	0.00%	$35K	—
167	Walleye Capital LLC	10,000	0.00%	$35K	NEW
168	ROYAL BANK OF CANADA	8,605	0.00%	$30K	-3,680 (-30.0%)
169	Redwood Park Advisors LLC	7,140	0.00%	$25K	—
170	JONES FINANCIAL COMPANIES LLLP	5,649	0.00%	$19K	-3,519 (-38.4%)
171	GF FUND MANAGEMENT CO. LTD.	5,637	0.00%	$20K	-321 (-5.4%)
172	IFP Advisors, Inc	5,545	0.00%	$19K	+145 (+2.7%)
173	FIFTH THIRD BANCORP	5,524	0.00%	$19K	NEW
174	Washington Trust Advisors, Inc.	5,000	0.00%	$17K	—
175	Tower Research Capital LLC (TRC)	4,992	0.00%	$17K	-39,069 (-88.7%)
176	SIGNATUREFD, LLC	3,507	0.00%	$12K	—
177	Pacer Advisors, Inc.	3,286	0.00%	$11K	NEW
178	Blue Trust, Inc.	3,235	0.00%	$11K	—
179	BNP PARIBAS ASSET MANAGEMENT Holding S.A.	3,140	0.00%	$11K	+178 (+6.0%)
180	INTERNATIONAL ASSETS INVESTMENT MANAGEMENT, LLC	3,000	0.00%	$11K	—
181	Federation des caisses Desjardins du Quebec	2,700	0.00%	$9K	+1,700 (+170.0%)
182	True Wealth Design, LLC	2,490	0.00%	$9K	—
183	Farther Finance Advisors, LLC	2,490	0.00%	$9K	—
184	EverSource Wealth Advisors, LLC	2,285	0.00%	$8K	-1,100 (-32.5%)
185	Essential Partners LLC	2,241	0.00%	$8K	-1,059 (-32.1%)
186	SBI Securities Co., Ltd.	2,233	0.00%	$8K	+105 (+4.9%)
187	Hurley Capital, LLC	2,000	0.00%	$7K	—
188	Allworth Financial LP	1,338	0.00%	$5K	+116 (+9.5%)
189	Archer Investment Corp	1,274	0.00%	$4K	NEW
190	Fortitude Family Office, LLC	1,237	0.00%	$4K	+1,088 (+730.2%)
191	COMPASS FINANCIAL MANAGEMENT LLC	1,095	0.00%	$4K	NEW
192	Triumph Capital Management	1,000	0.00%	$3K	—
193	Physician Wealth Advisors, Inc.	975	0.00%	$3K	—
194	Caitong International Asset Management Co., Ltd	786	0.00%	$3K	+276 (+54.1%)
195	Sterling Capital Management LLC	645	0.00%	$2K	-4,464 (-87.4%)
196	Smartleaf Asset Management LLC	532	0.00%	$2K	—
197	ROTHSCHILD INVESTMENT LLC	510	0.00%	$2K	+200 (+64.5%)
198	HUNTINGTON NATIONAL BANK	400	0.00%	$1K	NEW
199	SJS Investment Consulting Inc.	367	0.00%	$1K	NEW
200	Optiver Holding B.V.	357	0.00%	$1K	-204 (-36.4%)
201	State of Wyoming	307	0.00%	$1K	NEW
202	NORTHWESTERN MUTUAL WEALTH MANAGEMENT CO	200	0.00%	$698	NEW
203	Parkside Financial Bank & Trust	186	0.00%	$650	—
204	Rialto Wealth Management, LLC	145	0.00%	$507	NEW
205	US BANCORP \DE\	107	0.00%	$373	-587 (-84.6%)
206	BARTLETT & CO. WEALTH MANAGEMENT LLC	100	0.00%	$349	—
207	CREATIVE FINANCIAL DESIGNS INC /ADV	100	0.00%	$349	—
208	Covestor Ltd	87	0.00%	$0	+61 (+234.6%)
209	HOLLENCREST CAPITAL MANAGEMENT	50	0.00%	$175	NEW
210	Axiom Investment Management LLC	20	0.00%	$70	NEW
211	Keating Financial Advisory Services, Inc.	1	0.00%	$3	NEW
212	Activest Wealth Management	0	0.00%	$0	-16,300 (-100.0%)

Exited since 2026-03-31 (24 filers; largest 24 shown)

BAILLIE GIFFORD & CO	−6,609,065
Balyasny Asset Management L.P.	−1,033,804
Susquehanna Portfolio Strategies, LLC	−167,503
JANE STREET GROUP, LLC	−132,715
Virtu Financial LLC	−109,865
Jump Financial, LLC	−108,475
Qube Research & Technologies Ltd	−100,082
Engineers Gate Manager LP	−90,171
CWM, LLC	−84,445
Headlands Technologies LLC	−62,055
ExodusPoint Capital Management, LP	−61,659
JANUS HENDERSON GROUP PLC	−58,189
FRANKLIN RESOURCES INC	−57,909
Modus Advisors, LLC	−55,000
EVOKE WEALTH, LLC	−38,184
Focus Partners Advisor Solutions, LLC	−11,330
Dynamic Technology Lab Private Ltd	−10,648
Hudson Bay Capital Management LP	−10,000
Atlantic Union Bankshares Corp	−5,012
QUADRANT CAPITAL GROUP LLC	−1,480
Rachor Investment Advisory Services, LLC	−369
Truvestments Capital LLC	−300
GAMMA Investing LLC	−222
Sunbelt Securities, Inc.	−22

Large holders from 13D/13G (latest per reporting person, last 2 years)

Filed when a holder crosses 5% or changes materially, so often more current than the quarter-end 13F. Percentages are the filer's own, against the share count they used.

Reporting person	Form	Filed	Event	Shares	% of class
ARCH Venture Partners IX Overage, L.P.	SCHEDULE 13G/A	2026-08-14	2026-06-30	45,860,681	15.3%
Steven Gillis	SCHEDULE 13G/A	2026-08-14	2026-06-30	45,860,681	15.3%
ARCH Venture Fund X, L.P.	SCHEDULE 13G/A	2026-08-14	2026-06-30	45,860,681	15.3%
ARCH Venture Fund X Overage, L.P.	SCHEDULE 13G/A	2026-08-14	2026-06-30	45,860,681	15.3%
ARCH Venture Partners IX, LLC	SCHEDULE 13G/A	2026-08-14	2026-06-30	45,860,681	15.3%
ARCH Venture Partners IX, L.P.	SCHEDULE 13G/A	2026-08-14	2026-06-30	45,860,681	15.3%
ARCH Venture Fund IX Overage, L.P.	SCHEDULE 13G/A	2026-08-14	2026-06-30	45,860,681	15.3%
ARCH Venture Partners X, L.P.	SCHEDULE 13G/A	2026-08-14	2026-06-30	45,860,681	15.3%
ARCH Venture Fund IX, L.P.	SCHEDULE 13G/A	2026-08-14	2026-06-30	45,860,681	15.3%
ARCH Venture Partners X Overage, L.P.	SCHEDULE 13G/A	2026-08-14	2026-06-30	45,860,681	15.3%
ARCH Venture Partners X, LLC	SCHEDULE 13G/A	2026-08-14	2026-06-30	45,860,681	15.3%
Clinton Bybee	SCHEDULE 13G/A	2026-08-14	2026-06-30	45,860,681	15.3%
Keith Crandell	SCHEDULE 13G/A	2026-08-14	2026-06-30	45,860,681	15.3%
Kristina Burow	SCHEDULE 13G/A	2026-08-14	2026-06-30	45,860,681	15.3%
Robert Nelsen	SCHEDULE 13G/A	2026-08-14	2026-06-30	46,173,125	15.4%
RA Capital Healthcare Fund, L.P.	SCHEDULE 13G	2026-05-21	2026-05-14	18,750,000	6.3%
RA Capital Management, L.P.	SCHEDULE 13G	2026-05-21	2026-05-14	18,750,000	6.3%
Rajeev Shah	SCHEDULE 13G	2026-05-21	2026-05-14	18,750,000	6.3%
Peter Kolchinsky	SCHEDULE 13G	2026-05-21	2026-05-14	18,750,000	6.3%
BlackRock, Inc.	SCHEDULE 13G	2026-01-21	2025-12-31	13,643,304	5.1%
The Vanguard Group	SCHEDULE 13G/A	2025-01-31	2024-12-31	10,747,760	4.81%

Source: SEC Form 13F-HR information tables for the quarter ending 2026-06-30 (filed within 45 days of quarter end; amendments applied; values normalised to dollars), the share count from the company's latest 10-K/10-Q XBRL cover page, and Schedule 13D/13G filings. Each row is a legal 13F filer as filed — related entities (e.g. Vanguard's advisers) are not merged. Retail brokerage accounts are not reported on 13F, so the remainder is mostly retail and insiders.