Institutional HoldersBeta

Who holds a company, from every 13F filed for the quarter, one row per filer exactly as filed, against the latest share count the company reported.

Scholar Rock Holding Corp

CIK 0001727196SRRK· quarter ending 2026-06-30

Shares outstanding

121,785,282

as of 2026-08-03 · 10-Q cover page, filed 2026-08-06

Held by 13F filers

138,724,776

113.9% of shares outstanding

Holders

307

+32 vs 2026-03-31 · 57 new, 25 exited

Value

$7.6B

shares +3.7% vs prior quarter

13F holdings exceed the share count. This is normal for heavily shorted stocks: shares lent to short sellers are reported by the lender and again by whoever bought them. Related filers occasionally report the same position twice as well.

Share classes (cover page of the 10-Q filed 2026-08-06, as of 2026-08-03)

Class	Listed	Shares outstanding	Held by 13F filers	% of class	Holders	CUSIP
Common stock	SRRK · NASDAQ	121,785,282	138,724,776	113.9%	307	80706P103

Each class is compared with its own share count; classes are not added together. A class that is not exchange-listed cannot be held by 13F filers.

Securities (CUSIPs held in 13F this quarter)

tick to combine

Count	CUSIP	Class (as filers write it)	Holders	Shares held	Class shares	% of class	Value	Options	Mapped via
	80706P103	COM	307	138,724,776	121,785,282	113.9%	$7.6B	4 call / 5 put	13DG	holders →

Totals combine the ticked CUSIPs and update as you tick: common-stock classes by default; preferreds, notes, warrants and depositary shares are listed but not counted. "holders →" shows a single CUSIP on its own. Bonds are held as a principal amount, not shares. Options positions are never counted as holdings.

Top holders (250 of 307 · 80706P103)

change vs 2026-03-31

#	Filer	Shares	% of class	Value	Change
1	FMR LLC	17,995,241	14.78%	$989.7M	+752,089 (+4.4%)
2	Siren, L.L.C.	9,575,013	7.86%	$526.6M	-1,250,000 (-11.5%)
3	BlackRock, Inc.	9,494,084	7.80%	$522.2M	+2,024,791 (+27.1%)
4	SAMSARA BIOCAPITAL, LLC	6,897,652	5.66%	$379.4M	—
5	PRICE T ROWE ASSOCIATES INC /MD/	6,794,837	5.58%	$373.7M	+588,219 (+9.5%)
6	WELLINGTON MANAGEMENT GROUP LLP	6,727,085	5.52%	$370.0M	+9,430 (+0.1%)
7	Orbis Allan Gray Ltd	5,933,533	4.87%	$326.3M	+1,753,550 (+42.0%)
8	VANGUARD CAPITAL MANAGEMENT LLC	4,767,880	3.91%	$262.2M	+876,533 (+22.5%)
9	STATE STREET CORP	4,728,681	3.88%	$260.1M	+697,364 (+17.3%)
10	Redmile Group, LLC	4,311,092	3.54%	$237.1M	-4,755,529 (-52.5%)
11	NORGES BANK	2,769,910	2.27%	$152.3M	NEW
12	GEODE CAPITAL MANAGEMENT, LLC	2,753,787	2.26%	$151.5M	+604,751 (+28.1%)
13	MASSACHUSETTS FINANCIAL SERVICES CO /MA/	2,607,348	2.14%	$143.4M	NEW
14	Bellevue Group AG	2,449,547	2.01%	$134.7M	-1,135,026 (-31.7%)
15	JENNISON ASSOCIATES LLC	2,358,587	1.94%	$129.7M	-981,905 (-29.4%)
16	Jupiter Topco LLC	2,242,106	1.84%	$123.3M	NEW
17	Hood River Capital Management LLC	2,224,788	1.83%	$122.4M	+175,109 (+8.5%)
18	Driehaus Capital Management LLC	2,205,618	1.81%	$121.3M	+285,385 (+14.9%)
19	EVENTIDE ASSET MANAGEMENT, LLC	2,111,410	1.73%	$116.1M	-85,975 (-3.9%)
20	Polar Capital Holdings Plc	1,878,580	1.54%	$103.3M	-105,048 (-5.3%)
21	Holocene Advisors, LP	1,755,978	1.44%	$96.6M	-134,949 (-7.1%)
22	ADAGE CAPITAL PARTNERS GP, L.L.C.	1,731,402	1.42%	$95.2M	+1,031,402 (+147.3%)
23	MORGAN STANLEY	1,538,776	1.26%	$84.6M	+1,319,749 (+602.6%)
24	Woodline Partners LP	1,500,470	1.23%	$82.5M	—
25	GOLDMAN SACHS GROUP INC	1,411,477	1.16%	$77.6M	+12,494 (+0.9%)
26	Capital World Investors	1,160,409	0.95%	$63.8M	+31,657 (+2.8%)
27	Clearbridge Investments, LLC	1,059,776	0.87%	$58.3M	+368,358 (+53.3%)
28	VANGUARD PORTFOLIO MANAGEMENT LLC	1,027,357	0.84%	$56.5M	+305,613 (+42.3%)
29	BNP PARIBAS ASSET MANAGEMENT Holding S.A.	979,845	0.80%	$53.9M	-2,070 (-0.2%)
30	AMERICAN CENTURY COMPANIES INC	975,197	0.80%	$53.6M	+268,096 (+37.9%)
31	NORTHERN TRUST CORP	974,576	0.80%	$53.6M	+210,773 (+27.6%)
32	BANK OF AMERICA CORP /DE/	972,257	0.80%	$53.5M	-364,375 (-27.3%)
33	Pictet Asset Management Holding SA	911,075	0.75%	$50.1M	+35,991 (+4.1%)
34	VOYA INVESTMENT MANAGEMENT LLC	890,607	0.73%	$49.0M	+165,198 (+22.8%)
35	FRANKLIN RESOURCES INC	878,726	0.72%	$48.3M	+851,844 (+3168.8%)
36	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	864,286	0.71%	$47.5M	+163,275 (+23.3%)
37	Integral Health Asset Management, LLC	750,000	0.62%	$41.3M	+250,000 (+50.0%)
38	FEDERATED HERMES, INC.	734,513	0.60%	$40.4M	-63,400 (-7.9%)
39	VANGUARD FIDUCIARY TRUST CO	730,083	0.60%	$40.2M	+141,035 (+23.9%)
40	BNP PARIBAS FINANCIAL MARKETS	717,512	0.59%	$39.5M	-6,363 (-0.9%)
41	Rock Springs Capital Management LP	715,452	0.59%	$39.3M	-24,364 (-3.3%)
42	Casdin Capital, LLC	665,000	0.55%	$36.6M	+315,000 (+90.0%)
43	Nuveen, LLC	651,749	0.54%	$35.8M	+70,095 (+12.1%)
44	LOOMIS SAYLES & CO L P	596,055	0.49%	$32.8M	-42,574 (-6.7%)
45	Ensign Peak Advisors, Inc	579,052	0.48%	$31.8M	-138,201 (-19.3%)
46	Eagle Health Investments LP	555,272	0.46%	$30.5M	+61,253 (+12.4%)
47	UBS Group AG	511,170	0.42%	$28.1M	-168,614 (-24.8%)
48	Qube Research & Technologies Ltd	463,730	0.38%	$25.5M	NEW
49	Fisher Asset Management, LLC	439,447	0.36%	$24.2M	-18,570 (-4.1%)
50	MARSHALL WACE, LLP	430,500	0.35%	$23.7M	-629,775 (-59.4%)
51	Bank of New York Mellon Corp	365,218	0.30%	$20.1M	+132,546 (+57.0%)
52	CITADEL ADVISORS LLC	331,851	0.27%	$18.3M	-568,948 (-63.2%)
53	DEUTSCHE BANK AG\	303,268	0.25%	$16.7M	+61,474 (+25.4%)
54	Squarepoint Ops LLC	291,996	0.24%	$16.1M	+242,041 (+484.5%)
55	NAN FUNG TRINITY (HK) LTD	285,495	0.23%	$15.7M	—
56	ARMISTICE CAPITAL, LLC	278,000	0.23%	$15.3M	-58,959 (-17.5%)
57	Trexquant Investment LP	275,712	0.23%	$15.2M	+198,964 (+259.2%)
58	First Turn Management, LLC	271,227	0.22%	$14.9M	-175,163 (-39.2%)
59	AQR CAPITAL MANAGEMENT LLC	247,521	0.20%	$13.6M	+35,561 (+16.8%)
60	D. E. Shaw & Co., Inc.	245,027	0.20%	$13.5M	+230,383 (+1573.2%)
61	RAYMOND JAMES FINANCIAL INC	240,665	0.20%	$13.2M	-12,934 (-5.1%)
62	STEMPOINT CAPITAL LP	239,146	0.20%	$13.2M	-1,831,846 (-88.5%)
63	Candriam S.C.A.	216,146	0.18%	$11.9M	-9,852 (-4.4%)
64	Universal- Beteiligungs- und Servicegesellschaft mbH	209,991	0.17%	$11.5M	+32,614 (+18.4%)
65	Senator Investment Group LP	205,000	0.17%	$11.3M	NEW
66	Logos Global Management LP	200,000	0.16%	$11.0M	NEW
67	Susquehanna Portfolio Strategies, LLC	199,052	0.16%	$10.9M	+150,868 (+313.1%)
68	SEGALL BRYANT & HAMILL, LLC	188,588	0.15%	$10.4M	NEW
69	JPMORGAN CHASE & CO	177,692	0.15%	$10.0M	+3,273 (+1.9%)
70	SEI INVESTMENTS CO	173,623	0.14%	$9.5M	+30,264 (+21.1%)
71	Granahan Investment Management, LLC	163,759	0.13%	$9.0M	+7,445 (+4.8%)
72	Swiss National Bank	149,800	0.12%	$8.2M	+26,600 (+21.6%)
73	RHUMBLINE ADVISERS	145,460	0.12%	$8.0M	+32,959 (+29.3%)
74	ALLIANCEBERNSTEIN L.P.	139,820	0.11%	$6.9M	+39,130 (+38.9%)
75	PEREGRINE CAPITAL MANAGEMENT LLC	139,534	0.11%	$7.7M	-7,072 (-4.8%)
76	AMERIPRISE FINANCIAL INC	133,482	0.11%	$7.3M	+95,595 (+252.3%)
77	GordonMD Global Investments LP	132,500	0.11%	$7.3M	—
78	Russell Investments Group, Ltd.	130,514	0.11%	$7.2M	+116,774 (+849.9%)
79	MGO ONE SEVEN LLC	125,077	0.10%	$6.9M	NEW
80	iA Global Asset Management Inc.	122,812	0.10%	$6.8M	-400 (-0.3%)
81	MANUFACTURERS LIFE INSURANCE COMPANY, THE	122,223	0.10%	$6.7M	-51,542 (-29.7%)
82	TD Asset Management Inc	120,364	0.10%	$6.6M	-102,700 (-46.0%)
83	WELLS FARGO & COMPANY/MN	115,011	0.09%	$6.3M	+82,321 (+251.8%)
84	CITIGROUP INC	113,031	0.09%	$6.2M	+74,303 (+191.9%)
85	UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC	111,186	0.09%	$6.1M	+8,274 (+8.0%)
86	EFG International AG	110,634	0.09%	$6.1M	-2,096 (-1.9%)
87	Man Group plc	104,346	0.09%	$5.7M	+42,228 (+68.0%)
88	Ghisallo Capital Management LLC	100,000	0.08%	$5.5M	NEW
89	Artia Global Partners LP	96,285	0.08%	$5.3M	—
90	SPHERA FUNDS MANAGEMENT LTD.	94,265	0.08%	$5.2M	—
91	Invesco Ltd.	94,156	0.08%	$5.2M	-25,441 (-21.3%)
92	RENAISSANCE TECHNOLOGIES LLC	91,500	0.08%	$5.0M	NEW
93	FIDEURAM - INTESA SANPAOLO PRIVATE BANKING S.P.A.	91,018	0.07%	$5.0M	-7,682 (-7.8%)
94	Nicholas Investment Partners, LP	90,334	0.07%	$5.0M	+7,823 (+9.5%)
95	BEACONLIGHT CAPITAL, LLC	87,893	0.07%	$4.8M	NEW
96	CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM	85,644	0.07%	$4.7M	+10,728 (+14.3%)
97	VANGUARD ASSET MANAGEMENT, Ltd	79,737	0.07%	$4.4M	+15,120 (+23.4%)
98	StoneCrest Wealth Management, Inc.	78,780	0.06%	$4.3M	+7,866 (+11.1%)
99	Aisling Capital Management LP	77,031	0.06%	$4.2M	—
100	Hudson Bay Capital Management LP	75,000	0.06%	$4.1M	-8,450 (-10.1%)
101	MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd.	72,527	0.06%	$4.0M	+10,621 (+17.2%)
102	Cinctive Capital Management LP	71,909	0.06%	$4.0M	-100,626 (-58.3%)
103	MetLife Investment Management, LLC	65,038	0.05%	$3.6M	+17,575 (+37.0%)
104	Rafferty Asset Management, LLC	62,608	0.05%	$3.4M	-41,848 (-40.1%)
105	Legal & General Group Plc	61,144	0.05%	$3.4M	+11,230 (+22.5%)
106	ALGERT GLOBAL LLC	58,350	0.05%	$3.2M	+46,220 (+381.0%)
107	POLEN CAPITAL MANAGEMENT LLC	52,132	0.04%	$2.9M	+181 (+0.3%)
108	NEW YORK STATE COMMON RETIREMENT FUND	50,933	0.04%	$2.8M	+11,600 (+29.5%)
109	Moody Aldrich Partners LLC	47,228	0.04%	$2.6M	-12,973 (-21.5%)
110	NOMURA ASSET MANAGEMENT INTERNATIONAL INC.	46,054	0.04%	$2.5M	-1,766 (-3.7%)
111	KVP Capital Advisors, LP	45,000	0.04%	$2.5M	—
112	STATE OF WISCONSIN INVESTMENT BOARD	43,020	0.04%	$2.4M	+5,273 (+14.0%)
113	Vanguard Global Advisers, LLC	42,850	0.04%	$2.4M	+9,066 (+26.8%)
114	Jasper Ridge Partners, L.P.	42,455	0.03%	$2.3M	—
115	XTX Topco Ltd	41,822	0.03%	$2.3M	-58,603 (-58.4%)
116	PRUDENTIAL FINANCIAL INC	39,170	0.03%	$2.2M	+25,555 (+187.7%)
117	DARK FOREST CAPITAL MANAGEMENT LP	38,420	0.03%	$2.1M	+22,195 (+136.8%)
118	Balyasny Asset Management L.P.	37,372	0.03%	$2.1M	-112,342 (-75.0%)
119	Creative Planning	34,970	0.03%	$1.9M	+5,778 (+19.8%)
120	KENNEDY CAPITAL MANAGEMENT LLC	34,466	0.03%	$1.9M	-2,986 (-8.0%)
121	LPL Financial LLC	33,444	0.03%	$1.8M	+16,480 (+97.1%)
122	Police & Firemen's Retirement System of New Jersey	32,981	0.03%	$1.8M	+9,365 (+39.7%)
123	PROFUND ADVISORS LLC	32,759	0.03%	$1.8M	-14,334 (-30.4%)
124	Zurcher Kantonalbank (Zurich Cantonalbank)	32,624	0.03%	$1.8M	+3,446 (+11.8%)
125	Handelsbanken Fonder AB	32,200	0.03%	$1.8M	+8,700 (+37.0%)
126	Ishara Investments LP	30,750	0.03%	$1.7M	-26,650 (-46.4%)
127	STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM	30,232	0.02%	$1.7M	+10,485 (+53.1%)
128	GUGGENHEIM CAPITAL LLC	29,717	0.02%	$1.6M	-6,759 (-18.5%)
129	BARCLAYS PLC	29,160	0.02%	$1.6M	-13,891 (-32.3%)
130	Pathstone Holdings, LLC	28,784	0.02%	$1.6M	NEW
131	Aquatic Capital Management LLC	28,447	0.02%	$1.6M	NEW
132	TUDOR INVESTMENT CORP ET AL	26,226	0.02%	$1.4M	-3,982 (-13.2%)
133	INTECH INVESTMENT MANAGEMENT LLC	25,782	0.02%	$1.4M	+257 (+1.0%)
134	TEACHERS RETIREMENT SYSTEM OF THE STATE OF KENTUCKY	25,243	0.02%	$1.4M	—
135	D.A. DAVIDSON & CO.	24,520	0.02%	$1.3M	-312 (-1.3%)
136	State of New Jersey Common Pension Fund D	24,145	0.02%	$1.3M	+2,791 (+13.1%)
137	Engineers Gate Manager LP	23,933	0.02%	$1.3M	+16,245 (+211.3%)
138	E. Ohman J:or Asset Management AB	23,309	0.02%	$1.3M	+1,173 (+5.3%)
139	AMI ASSET MANAGEMENT CORP	21,705	0.02%	$1.2M	-6,825 (-23.9%)
140	ARIZONA STATE RETIREMENT SYSTEM	20,605	0.02%	$1.1M	+3,442 (+20.1%)
141	ENVESTNET ASSET MANAGEMENT INC	20,527	0.02%	$1.1M	+1,046 (+5.4%)
142	Quadrature Capital Ltd	19,904	0.02%	$1.1M	NEW
143	Quantinno Capital Management LP	19,729	0.02%	$1.1M	+8,457 (+75.0%)
144	Values First Advisors, Inc.	19,463	0.02%	$1.1M	+613 (+3.3%)
145	China Universal Asset Management Co., Ltd.	19,071	0.02%	$1.0M	+969 (+5.4%)
146	Vanguard Investments Australia, Ltd.	19,032	0.02%	$1.0M	+3,319 (+21.1%)
147	SG Americas Securities, LLC	18,982	0.02%	$1.0M	+10,357 (+120.1%)
148	Erste Asset Management GmbH	18,600	0.02%	$1.0M	—
149	ProShare Advisors LLC	18,570	0.02%	$1.0M	+1,352 (+7.9%)
150	MILLENNIUM MANAGEMENT LLC	18,078	0.01%	$994K	NEW
151	Lighthouse Investment Partners, LLC	18,000	0.01%	$990K	+5,000 (+38.5%)
152	DNB Asset Management AS	17,972	0.01%	$988K	-3,986 (-18.2%)
153	Y-Intercept (Hong Kong) Ltd	17,332	0.01%	$953K	NEW
154	KLP KAPITALFORVALTNING AS	16,900	0.01%	$930K	+3,100 (+22.5%)
155	GSA CAPITAL PARTNERS LLP	15,838	0.01%	$871K	-4,627 (-22.6%)
156	SUSQUEHANNA INTERNATIONAL GROUP, LLP	15,504	0.01%	$853K	-32,732 (-67.9%)
157	Scientech Research LLC	15,341	0.01%	$844K	-10,947 (-41.6%)
158	Legato Capital Management LLC	14,457	0.01%	$795K	+365 (+2.6%)
159	Allianz Asset Management GmbH	14,300	0.01%	$787K	+4,900 (+52.1%)
160	Mariner, LLC	14,108	0.01%	$776K	+1,987 (+16.4%)
161	SBI Okasan Asset Management Co.Ltd.	14,000	0.01%	$769K	—
162	Clearstead Advisors, LLC	13,058	0.01%	$718K	-13,016 (-49.9%)
163	Virtu Financial LLC	12,095	0.01%	$665K	-4,446 (-26.9%)
164	GLENMEDE TRUST CO NA	11,205	0.01%	$616K	+960 (+9.4%)
165	VICTORY CAPITAL MANAGEMENT INC	11,143	0.01%	$613K	-14,727 (-56.9%)
166	Three Seasons Wealth, LLC	11,068	0.01%	$609K	-80 (-0.7%)
167	XPONANCE LLC	10,990	0.01%	$604K	+2,899 (+35.8%)
168	BLAIR WILLIAM & CO/IL	10,546	0.01%	$580K	+243 (+2.4%)
169	KEYBANK NATIONAL ASSOCIATION/OH	10,415	0.01%	$573K	+51 (+0.5%)
170	Ameritas Investment Partners, Inc.	10,249	0.01%	$564K	+3,105 (+43.5%)
171	MERCER GLOBAL ADVISORS INC /ADV	10,071	0.01%	$554K	+2,876 (+40.0%)
172	STRS OHIO	9,900	0.01%	$545K	+6,200 (+167.6%)
173	SYON CAPITAL LLC	9,782	0.01%	$538K	+588 (+6.4%)
174	TWO SIGMA INVESTMENTS, LP	9,540	0.01%	$525K	-169,132 (-94.7%)
175	Tidal Investments LLC	9,521	0.01%	$524K	-270 (-2.8%)
176	Tema ETFs LLC	9,521	0.01%	$524K	-252 (-2.6%)
177	Blackstone Inc.	9,262	0.01%	$509K	NEW
178	E Fund Management Co., Ltd.	9,256	0.01%	$509K	-4,193 (-31.2%)
179	VERUS CAPITAL PARTNERS, LLC	9,255	0.01%	$509K	-1,235 (-11.8%)
180	Vanguard Personalized Indexing Management, LLC	8,946	0.01%	$492K	+329 (+3.8%)
181	Jain Global LLC	8,784	0.01%	$483K	NEW
182	TEACHER RETIREMENT SYSTEM OF TEXAS	8,730	0.01%	$480K	+681 (+8.5%)
183	Cerity Partners LLC	8,280	0.01%	$455K	+49 (+0.6%)
184	PRINCIPAL FINANCIAL GROUP INC	8,188	0.01%	$450K	+2,075 (+33.9%)
185	QP WEALTH MANAGEMENT, LLC	8,116	0.01%	$446K	NEW
186	CANADA LIFE ASSURANCE Co	8,053	0.01%	$442K	+1,185 (+17.3%)
187	INCEPTIONR LLC	8,035	0.01%	$442K	NEW
188	MN Wealth Advisors, LLC	8,030	0.01%	$442K	-100 (-1.2%)
189	HIMENSION CAPITAL (SINGAPORE) PTE. LTD.	7,721	0.01%	$425K	NEW
190	CAPTRUST FINANCIAL ADVISORS	7,720	0.01%	$425K	NEW
191	VARCOV Co.	7,530	0.01%	$414K	NEW
192	Virtus Investment Advisers, LLC	7,406	0.01%	$407K	+1,590 (+27.3%)
193	FIRST TRUST ADVISORS LP	7,075	0.01%	$389K	+1,751 (+32.9%)
194	M&T Bank Corp	7,039	0.01%	$387K	-1,238 (-15.0%)
195	Campbell & CO Investment Adviser LLC	6,904	0.01%	$380K	NEW
196	Caprock Group, LLC	6,867	0.01%	$378K	-363 (-5.0%)
197	MARTINGALE ASSET MANAGEMENT L P	6,704	0.01%	$369K	-2 (-0.0%)
198	Yorktown Management & Research Co Inc	6,400	0.01%	$352K	NEW
199	Spire Wealth Management	6,303	0.01%	$347K	—
200	CIBC Bancorp USA Inc.	6,182	0.01%	$340K	+1,791 (+40.8%)
201	ALLSTATE CORP	6,179	0.01%	$340K	NEW
202	NEUBERGER BERMAN GROUP LLC	6,131	0.01%	$337K	-93 (-1.5%)
203	Modern Wealth Management, LLC	6,024	0.00%	$331K	NEW
204	Corient Private Wealth LP	6,006	0.00%	$330K	+990 (+19.7%)
205	ACT CAPITAL MANAGEMENT, LLC	6,000	0.00%	$330K	-4,800 (-44.4%)
206	Magnetar Financial LLC	5,864	0.00%	$323K	+1,085 (+22.7%)
207	PUBLIC EMPLOYEES RETIREMENT ASSOCIATION OF COLORADO	5,738	0.00%	$316K	—
208	JONES FINANCIAL COMPANIES LLLP	5,722	0.00%	$313K	+2,372 (+70.8%)
209	WEALTH ENHANCEMENT ADVISORY SERVICES, LLC	5,656	0.00%	$321K	+578 (+11.4%)
210	ROYAL BANK OF CANADA	5,437	0.00%	$300K	+1,106 (+25.5%)
211	Fieldview Capital Management, LLC	5,379	0.00%	$296K	-9,269 (-63.3%)
212	Mirae Asset Global Investments Co., Ltd.	5,359	0.00%	$295K	+38 (+0.7%)
213	Tower Research Capital LLC (TRC)	5,174	0.00%	$285K	-8,821 (-63.0%)
214	Orion Porfolio Solutions, LLC	5,045	0.00%	$277K	+198 (+4.1%)
215	Caption Management, LLC	5,000	0.00%	$275K	NEW
216	National Philanthropic Trust	5,000	0.00%	$275K	—
217	Welch & Forbes LLC	5,000	0.00%	$275K	—
218	State of Wyoming	4,818	0.00%	$265K	NEW
219	Swiss Life Asset Management Ltd	4,563	0.00%	$251K	NEW
220	Penserra Capital Management LLC	4,531	0.00%	$249K	+2,526 (+126.0%)
221	Shay Capital LLC	4,500	0.00%	$248K	-23,500 (-83.9%)
222	LANARK FINANCIAL, INC.	4,479	0.00%	$246K	-13 (-0.3%)
223	O'SHAUGHNESSY ASSET MANAGEMENT, LLC	4,245	0.00%	$233K	NEW
224	SUSQUEHANNA FUNDAMENTAL INVESTMENTS, LLC	4,225	0.00%	$232K	NEW
225	Nykredit A/S	3,904	0.00%	$215K	NEW
226	PSP Research LLC	3,827	0.00%	$210K	NEW
227	Empowered Funds, LLC	3,766	0.00%	$207K	NEW
228	Quarry LP	3,750	0.00%	$206K	-3,250 (-46.4%)
229	Merit Financial Group, LLC	3,730	0.00%	$205K	NEW
230	OSAIC HOLDINGS, INC.	3,727	0.00%	$205K	+245 (+7.0%)
231	CIBC Asset Management Inc	3,705	0.00%	$204K	NEW
232	LOS ANGELES CAPITAL MANAGEMENT LLC	3,697	0.00%	$203K	—
233	Chung Wu Investment Group, LLC	3,500	0.00%	$193K	-700 (-16.7%)
234	Arax Advisory Partners	3,243	0.00%	$178K	+3,157 (+3670.9%)
235	GROUP ONE TRADING LLC	3,004	0.00%	$165K	-2,405 (-44.5%)
236	Mitsubishi UFJ Trust & Banking Corp	2,738	0.00%	$151K	NEW
237	Persistent Asset Partners Ltd	2,495	0.00%	$137K	NEW
238	BESSEMER GROUP INC	2,287	0.00%	$125K	+12 (+0.5%)
239	GF FUND MANAGEMENT CO. LTD.	2,161	0.00%	$119K	-130 (-5.7%)
240	US BANCORP \DE\	2,057	0.00%	$113K	-492 (-19.3%)
241	KBC Group NV	2,055	0.00%	$113K	—
242	NISA INVESTMENT ADVISORS, LLC	2,044	0.00%	$112K	+595 (+41.1%)
243	SIGNATUREFD, LLC	1,799	0.00%	$99K	—
244	Bayforest Capital Ltd	1,723	0.00%	$95K	NEW
245	SIMPLEX TRADING, LLC	1,465	0.00%	$81K	NEW
246	Rockefeller Capital Management L.P.	1,428	0.00%	$79K	—
247	GAMMA Investing LLC	1,406	0.00%	$77K	+242 (+20.8%)
248	PNC Financial Services Group, Inc.	1,229	0.00%	$68K	-41 (-3.2%)
249	Pacer Advisors, Inc.	1,046	0.00%	$58K	NEW
250	Kemnay Advisory Services Inc.	959	0.00%	$53K	+122 (+14.6%)

Exited since 2026-03-31 (25 filers; largest 25 shown)

JANUS HENDERSON GROUP PLC	−2,236,837
Vestal Point Capital, LP	−1,324,422
Paradigm Biocapital Advisors LP	−1,226,080
JANE STREET GROUP, LLC	−560,084
ADAR1 Capital Management, LLC	−407,273
SILVERARC CAPITAL MANAGEMENT, LLC	−339,613
ExodusPoint Capital Management, LP	−67,068
SCHRODER INVESTMENT MANAGEMENT GROUP	−49,942
HRT FINANCIAL LP	−28,706
Mill Creek Capital Advisors, LLC	−12,664
WESBANCO BANK INC	−10,000
CWM, LLC	−9,164
Brevan Howard Capital Management LP	−7,735
FARALLON CAPITAL MANAGEMENT LLC	−7,000
Flaharty Asset Management, LLC	−6,000
WESTFIELD CAPITAL MANAGEMENT CO LP	−5,182
ELEVATION POINT WEALTH PARTNERS, LLC	−4,739
RWC Asset Management LLP	−4,504
Quantbot Technologies LP	−794
Hilton Head Capital Partners, LLC	−683
Red Tortoise LLC	−256
MAI Capital Management	−117
Advisory Services Network, LLC	−60
Root Financial Partners, LLC	−34
Wealth Preservation Advisors, LLC	−13

Large holders from 13D/13G (latest per reporting person, last 2 years)

Filed when a holder crosses 5% or changes materially, so often more current than the quarter-end 13F. Percentages are the filer's own, against the share count they used.

Reporting person	Form	Filed	Event	Shares	% of class
Jeremy C. Green	SCHEDULE 13G/A	2026-08-14	2026-06-30	4,311,092	3.6%
RedCo II Master Fund, L.P.	SCHEDULE 13G/A	2026-08-14	2026-06-30	0	0%
Redmile Group, LLC	SCHEDULE 13G/A	2026-08-14	2026-06-30	4,311,092	3.6%
Siren, L.L.C.	SCHEDULE 13G/A	2026-08-13	2026-06-30	9,575,013	8%
Invus Global Management, LLC	SCHEDULE 13G/A	2026-08-13	2026-06-30	9,575,013	8%
Invus Public Equities Advisors, LLC	SCHEDULE 13G/A	2026-08-13	2026-06-30	9,575,013	8%
Invus Public Equities, L.P.	SCHEDULE 13G/A	2026-08-13	2026-06-30	9,575,013	8%
Raymond Debbane	SCHEDULE 13G/A	2026-08-13	2026-06-30	9,575,013	8%
T. Rowe Price Associates, Inc.	SCHEDULE 13G/A	2026-05-15	2026-03-31	6,206,044	5.4%
The Vanguard Group	SCHEDULE 13G/A	2026-03-27	2026-03-13	0	0%
Wellington Group Holdings LLP	SCHEDULE 13G	2026-02-10	2025-12-31	5,759,428	5.6%
Wellington Investment Advisors Holdings LLP	SCHEDULE 13G	2026-02-10	2025-12-31	5,759,428	5.6%
Wellington Management Company LLP	SCHEDULE 13G	2026-02-10	2025-12-31	5,759,428	5.3%
Wellington Management Group LLP	SCHEDULE 13G	2026-02-10	2025-12-31	5,759,428	5.6%
Samsara BioCapital, L.P.	SCHEDULE 13D/A	2025-10-07	2025-10-03	6,367,614	6.6%
Samsara Opportunity Fund GP, LLC	SCHEDULE 13D/A	2025-10-07	2025-10-03	500,439	0.5%
Samsara Opportunity Fund, L.P.	SCHEDULE 13D/A	2025-10-07	2025-10-03	500,439	0.5%
Samsara BioCapital GP, LLC	SCHEDULE 13D/A	2025-10-07	2025-10-03	6,367,614	6.6%
Srinivas Akkaraju	SCHEDULE 13D/A	2025-10-07	2025-10-03	6,991,553	7.2%
Abigail P. Johnson	SCHEDULE 13G/A	2025-02-12	2024-12-31	14,114,029	15%
FMR LLC	SCHEDULE 13G/A	2025-02-12	2024-12-31	14,114,029	15%

Source: SEC Form 13F-HR information tables for the quarter ending 2026-06-30 (filed within 45 days of quarter end; amendments applied; values normalised to dollars), the share count from the company's latest 10-K/10-Q XBRL cover page, and Schedule 13D/13G filings. Each row is a legal 13F filer as filed — related entities (e.g. Vanguard's advisers) are not merged. Retail brokerage accounts are not reported on 13F, so the remainder is mostly retail and insiders.