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Tectonic Therapeutic, Inc.

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Who holds a company, from every 13F filed for the quarter, one row per filer exactly as filed, against the latest share count the company reported.

Tectonic Therapeutic, Inc.

CIK 0001681087TECX· quarter ending 2026-06-30
Shares outstanding
19,549,366
as of 2026-07-31 · 10-Q cover page, filed 2026-08-06
Held by 13F filers
13,964,835
71.4% of shares outstanding
Holders
122
+11 vs 2026-03-31 · 24 new, 13 exited
Value
$479.9M
shares +1.1% vs prior quarter

Share classes (cover page of the 10-Q filed 2026-08-06, as of 2026-07-31)

ClassListedShares outstandingHeld by 13F filers% of classHoldersCUSIP
Common stockTECX · NASDAQ19,549,36613,964,83571.4%122878972108

Each class is compared with its own share count; classes are not added together. A class that is not exchange-listed cannot be held by 13F filers.

Securities (CUSIPs held in 13F this quarter)

tick to combine
CountCUSIPClass (as filers write it)HoldersShares heldClass shares% of classValueOptionsMapped via
878972108COM12213,964,83519,549,36671.4%$479.9M2 call / 1 put13DGholders →

Totals combine the ticked CUSIPs and update as you tick: common-stock classes by default; preferreds, notes, warrants and depositary shares are listed but not counted. "holders →" shows a single CUSIP on its own. Bonds are held as a principal amount, not shares. Options positions are never counted as holdings.

Top holders (122 of 122 · 878972108)

change vs 2026-03-31
#FilerShares% of classValueChange
1FMR LLC2,830,37814.48%$97.3M+13,884 (+0.5%)
2TCG Crossover Management, LLC1,204,8916.16%$41.4M—
3Aberdeen Group plc1,141,8245.84%$39.3M—
4BlackRock, Inc.862,5924.41%$29.7M+2,240 (+0.3%)
5First Light Asset Management, LLC800,7264.10%$27.5M+152,983 (+23.6%)
6BAKER BROS. ADVISORS LP607,7883.11%$20.9M—
75AM Venture Management, LLC606,6603.10%$20.9M—
8BRAIDWELL LP596,9003.05%$20.5M-250,251 (-29.5%)
9VANGUARD CAPITAL MANAGEMENT LLC488,8052.50%$16.8M+15,273 (+3.2%)
10Vestal Point Capital, LP425,0002.17%$14.6M+97,000 (+29.6%)
11Bollard Group LLC302,9531.55%$10.4M—
12KENNEDY CAPITAL MANAGEMENT LLC282,2021.44%$9.7M-4,480 (-1.6%)
13GEODE CAPITAL MANAGEMENT, LLC270,4611.38%$9.3M+2,188 (+0.8%)
14ORBIMED ADVISORS LLC226,6001.16%$7.8M—
15STATE STREET CORP219,9081.12%$7.6M+6,403 (+3.0%)
16Ikarian Capital, LLC205,8371.05%$7.1M+48,300 (+30.7%)
17D. E. Shaw & Co., Inc.186,5500.95%$6.4M+70,430 (+60.7%)
18MARSHALL WACE, LLP172,1010.88%$5.9M-57,494 (-25.0%)
19MILLENNIUM MANAGEMENT LLC165,5250.85%$5.7M+107,177 (+183.7%)
20Squarepoint Ops LLC145,0280.74%$5.0M-19,391 (-11.8%)
21AMERIPRISE FINANCIAL INC142,4480.73%$4.9M-984 (-0.7%)
22WELLS FARGO & COMPANY/MN117,4280.60%$4.0M+4,764 (+4.2%)
23NORTHERN TRUST CORP113,9040.58%$3.9M+35,551 (+45.4%)
24Soleus Capital Management, L.P.101,6840.52%$3.5M-20,000 (-16.4%)
25Woodline Partners LP100,0000.51%$3.4M—
26VANGUARD PORTFOLIO MANAGEMENT LLC94,4140.48%$3.2M+30,807 (+48.4%)
27CITADEL ADVISORS LLC90,3930.46%$3.1MNEW
28GOLDMAN SACHS GROUP INC73,9240.38%$2.5M+11,498 (+18.4%)
29RAYMOND JAMES FINANCIAL INC72,6740.37%$2.5M+8,478 (+13.2%)
30SECTORAL ASSET MANAGEMENT INC71,0090.36%$2.4M+51,950 (+272.6%)
31VANGUARD FIDUCIARY TRUST CO68,3940.35%$2.4M+499 (+0.7%)
32JANE STREET GROUP, LLC65,8210.34%$2.3MNEW
33MORGAN STANLEY65,3730.33%$2.2M+525 (+0.8%)
34Connor, Clark & Lunn Investment Management Ltd.64,9400.33%$2.2M-2,054 (-3.1%)
35BOOTHBAY FUND MANAGEMENT, LLC60,7710.31%$2.1M+14,634 (+31.7%)
36JPMORGAN CHASE & CO55,3640.28%$1.8M-3,506 (-6.0%)
37PRICE T ROWE ASSOCIATES INC /MD/48,0010.25%$1.7M-116,054 (-70.7%)
38Tetragon Partners GP Ltd46,5160.24%$1.6M+8,928 (+23.8%)
39PFM Health Sciences, LP45,6310.23%$1.6M-498 (-1.1%)
40HRT FINANCIAL LP44,5400.23%$1.5MNEW
41Jump Financial, LLC43,4000.22%$1.5M+302 (+0.7%)
42Prosight Management, LP39,7310.20%$1.4M-40,141 (-50.3%)
43Trexquant Investment LP36,9910.19%$1.3MNEW
44Aldebaran Capital, LLC36,7970.19%$1.3M-387 (-1.0%)
45ExodusPoint Capital Management, LP35,2390.18%$1.2M-48,440 (-57.9%)
46WELLINGTON MANAGEMENT GROUP LLP31,4320.16%$1.1M+2,192 (+7.5%)
47CHARLES SCHWAB INVESTMENT MANAGEMENT INC30,4380.16%$1.0M+1,328 (+4.6%)
48MONIMUS CAPITAL MANAGEMENT, LP28,1430.14%$967K+1,390 (+5.2%)
49Bank of New York Mellon Corp25,2470.13%$868K+487 (+2.0%)
50ALPS ADVISORS INC19,1470.10%$658K+3,861 (+25.3%)
51Fisher Asset Management, LLC19,1220.10%$657KNEW
52AMERICAN CENTURY COMPANIES INC19,0010.10%$653K+6,467 (+51.6%)
53Quadrature Capital Ltd18,0670.09%$621KNEW
54SEI INVESTMENTS CO17,0290.09%$585K-19,841 (-53.8%)
55Clearstead Advisors, LLC16,6300.09%$572K-10,130 (-37.9%)
56UBS Group AG15,0550.08%$518K-14,932 (-49.8%)
57ADAR1 Capital Management, LLC14,5010.07%$498K+1,500 (+11.5%)
58RHUMBLINE ADVISERS13,7730.07%$473K-254 (-1.8%)
59Nuveen, LLC13,5140.07%$465K+1,481 (+12.3%)
60BANK OF AMERICA CORP /DE/11,0430.06%$380K-423 (-3.7%)
61Virtus Investment Advisers, LLC10,8060.06%$371K-2,993 (-21.7%)
62DIMENSIONAL FUND ADVISORS LP10,4430.05%$359K+366 (+3.6%)
63DEUTSCHE BANK AG\10,0390.05%$345K+694 (+7.4%)
64Brevan Howard Capital Management LP9,5730.05%$329KNEW
65BARCLAYS PLC9,1280.05%$314K+2,422 (+36.1%)
66Creative Planning8,9610.05%$308K-3,485 (-28.0%)
67FOX RUN MANAGEMENT, L.L.C.8,8650.05%$305KNEW
68Vanguard Global Advisers, LLC8,7650.04%$301K+4,801 (+121.1%)
69GSA CAPITAL PARTNERS LLP8,2750.04%$284K-10,598 (-56.2%)
70ALLIANCEBERNSTEIN L.P.7,4600.04%$231KNEW
71AlphaCentric Advisors LLC6,9480.04%$239K+99 (+1.4%)
72MetLife Investment Management, LLC6,7240.03%$231K—
73AQR CAPITAL MANAGEMENT LLC6,6170.03%$227K-10,317 (-60.9%)
74Invesco Ltd.6,3880.03%$220K-1,287 (-16.8%)
75STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM6,0600.03%$208KNEW
76Velan Capital Investment Management LP6,0000.03%$206KNEW
77Rangeley Capital, LLC6,0000.03%$206KNEW
78MANUFACTURERS LIFE INSURANCE COMPANY, THE5,9960.03%$206K-7,933 (-57.0%)
79Russell Investments Group, Ltd.5,5670.03%$191K+4,716 (+554.2%)
80CITIGROUP INC5,5480.03%$191K+4,401 (+383.7%)
81China Universal Asset Management Co., Ltd.5,5030.03%$189K-829 (-13.1%)
82NISA INVESTMENT ADVISORS, LLC5,4000.03%$186K+400 (+8.0%)
83BNP PARIBAS FINANCIAL MARKETS5,1460.03%$177K+2,330 (+82.7%)
84MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd.4,6940.02%$161K-521 (-10.0%)
85NEW YORK STATE COMMON RETIREMENT FUND4,6000.02%$158K—
86Police & Firemen's Retirement System of New Jersey2,6380.01%$91K—
87Quantbot Technologies LP1,8190.01%$63KNEW
88Ameritas Investment Partners, Inc.1,1220.01%$39K—
89US BANCORP \DE\1,0800.01%$37K-56 (-4.9%)
90Legal & General Group Plc1,0000.01%$34K—
91Mirae Asset Global Investments Co., Ltd.8440.00%$29K-135 (-13.8%)
92Chung Wu Investment Group, LLC8000.00%$28KNEW
93Arax Advisory Partners7250.00%$25KNEW
94Tower Research Capital LLC (TRC)6610.00%$23K-253 (-27.7%)
95State of Wyoming6010.00%$21KNEW
96HighMark Wealth Management LLC5870.00%$20K—
97SIMPLEX TRADING, LLC4390.00%$15K-912 (-67.5%)
98GF FUND MANAGEMENT CO. LTD.4000.00%$14K-15 (-3.6%)
99UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC3820.00%$13K—
100Rockefeller Capital Management L.P.3700.00%$13K—
101ROYAL BANK OF CANADA3110.00%$11KNEW
102GAMMA Investing LLC2900.00%$10K-40 (-12.1%)
103Federation des caisses Desjardins du Quebec2500.00%$9K-250 (-50.0%)
104Sterling Capital Management LLC1760.00%$6K-137 (-43.8%)
105CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM1410.00%$5K-454 (-76.3%)
106Axiom Investment Management LLC1250.00%$4KNEW
107Farther Finance Advisors, LLC760.00%$3K-26 (-25.5%)
108Allworth Financial LP520.00%$2K-13 (-20.0%)
109Marshall & Sterling Wealth Advisors Inc.500.00%$2K—
110PNC Financial Services Group, Inc.400.00%$1K+14 (+53.8%)
111Caldwell Trust Co200.00%$688—
112EASTERN BANK130.00%$447NEW
113HUNTINGTON NATIONAL BANK130.00%$447—
114SBI Securities Co., Ltd.110.00%$378NEW
115First Bancorp, Inc /ME/80.00%$275NEW
116EverSource Wealth Advisors, LLC70.00%$240-12 (-63.2%)
117NATIONAL BANK OF CANADA /FI/60.00%$205NEW
118Essential Partners LLC50.00%$172-32 (-86.5%)
119Zurcher Kantonalbank (Zurich Cantonalbank)30.00%$103—
120OSAIC HOLDINGS, INC.20.00%$69NEW
121ROTHSCHILD INVESTMENT LLC20.00%$69-9 (-81.8%)
122IFP Advisors, Inc20.00%$69NEW
Exited since 2026-03-31 (13 filers; largest 13 shown)
Opaleye Management Inc.−123,000
Point72 Asset Management, L.P.−68,598
TD Asset Management Inc−20,400
SUSQUEHANNA INTERNATIONAL GROUP, LLP−16,175
XTX Topco Ltd−11,621
CWM, LLC−1,829
Caption Management, LLC−1,449
Global Wealth Strategies & Associates−18
Fortitude Family Office, LLC−15
Sunbelt Securities, Inc.−8
MAI Capital Management−7
True Wealth Design, LLC−7
Root Financial Partners, LLC−5

Large holders from 13D/13G (latest per reporting person, last 2 years)

Filed when a holder crosses 5% or changes materially, so often more current than the quarter-end 13F. Percentages are the filer's own, against the share count they used.

Reporting personFormFiledEventShares% of class
TCG Crossover GP II, LLCSCHEDULE 13G2026-02-272026-02-12584,8823.1%
TCG Crossover GP III, LLCSCHEDULE 13G2026-02-272026-02-12584,8783.1%
TCG Crossover Fund II, L.P.SCHEDULE 13G2026-02-272026-02-12584,8823.1%
Chen YuSCHEDULE 13G2026-02-272026-02-121,169,7606.2%
TCG Crossover Fund III, L.P.SCHEDULE 13G2026-02-272026-02-12584,8783.1%
Aberdeen Group plcSCHEDULE 13G2026-01-292025-12-311,141,8246.1%
abrdn IncSCHEDULE 13G2026-01-292025-12-311,141,8246.1%
Deep Track Biotechnology Master Fund, Ltd.SCHEDULE 13G/A2025-11-142025-09-3000%
Deep Track Capital, LPSCHEDULE 13G/A2025-11-142025-09-3000%
EcoR1 Capital Fund Qualified, L.P.SCHEDULE 13G/A2025-11-142025-09-3000%
EcoR1 Capital, LLCSCHEDULE 13G/A2025-11-142025-09-3000%
Oleg NodelmanSCHEDULE 13G/A2025-11-142025-09-3000%
David KroinSCHEDULE 13G/A2025-11-142025-09-3000%
FMR LLCSCHEDULE 13G/A2025-05-122025-03-312,799,399.8315%
Abigail P. JohnsonSCHEDULE 13G/A2025-05-122025-03-312,799,399.8315%
Polaris Partners GP IX, L.L.C.SCHEDULE 13D/A2025-04-072025-04-03573,0623.1%
Chafen LuSCHEDULE 13D/A2025-04-072025-04-03186,1341%
Polaris Founders Capital Fund Management Co. I, L.L.C.SCHEDULE 13D/A2025-04-072025-04-0320,2620.1%
Polaris Founders Capital Fund I, L.P.SCHEDULE 13D/A2025-04-072025-04-0320,2620.1%
Polaris Partners IX, L.P.SCHEDULE 13D/A2025-04-072025-04-03573,0623.1%
TAS Partners LLCSCHEDULE 13D/A2025-04-072025-04-031,382,7237.4%
Polaris Founders Capital Fund II, L.P.SCHEDULE 13D/A2025-04-072025-04-0364,6520.3%
Polaris Founders Capital Fund Management Co. II, L.L.C.SCHEDULE 13D/A2025-04-072025-04-0364,6520.3%
VV Manager II, LLCSCHEDULE 13D/A2025-04-072025-03-0400%
Jonathan FlintSCHEDULE 13D/A2025-04-072025-04-0384,9140.5%
Terrance McGuireSCHEDULE 13D/A2025-04-072025-04-03657,9766.3%
Timothy A. SpringerSCHEDULE 13D/A2025-04-072025-04-034,313,55831.5%
Vida Ventures II-A, LLCSCHEDULE 13D/A2025-04-072025-03-0400%
Vida Ventures II, LLCSCHEDULE 13D/A2025-04-072025-03-0400%
BML Investment Partners, L.P.SCHEDULE 13G/A2025-02-132024-12-3100%

Source: SEC Form 13F-HR information tables for the quarter ending 2026-06-30 (filed within 45 days of quarter end; amendments applied; values normalised to dollars), the share count from the company's latest 10-K/10-Q XBRL cover page, and Schedule 13D/13G filings. Each row is a legal 13F filer as filed — related entities (e.g. Vanguard's advisers) are not merged. Retail brokerage accounts are not reported on 13F, so the remainder is mostly retail and insiders.