Flagship Pioneering, LLC

Annual Report of Proxy Voting Record of Registered Management Investment Company

Report of Holders of Securities

Beneficial ownership report for a passive holder of more than 5% (Schedule 13G)

Report of Holders of Securities

Beneficial ownership report for a passive holder of more than 5% (Schedule 13G)

Report of Holders of Securities

Report of Holders of Securities

Annual Report of Proxy Voting Record of Registered Management Investment Company

Report of Holders of Securities

Report of Holders of Securities

Report of Holders of Securities

Report of Holders of Securities

Annual Report of Proxy Voting Record of Registered Management Investment Company

Report of Holders of Securities

Report of Holders of Securities

Flagship Pioneering, LLC

Flagship Pioneering, LLC

AFEYAN NOUBAR; Flagship Pioneering, LLC; Flagship Pioneering Fund VI General Partner LLC; Nutritional Health LTP Fund General Partner LLC; Flagship Pioneering Fund VII General Partner LLC; Flagship Pioneering Special Opportunities Fund II General Partner LLC; FPN General Partner LLC; Flagship VentureLabs VI Manager LLC

AFEYAN NOUBAR; Flagship Pioneering, LLC; Flagship Pioneering Fund VI General Partner LLC; Nutritional Health LTP Fund General Partner LLC; Flagship Pioneering Fund VII General Partner LLC; Flagship Pioneering Special Opportunities Fund II General Partner LLC; FPN General Partner LLC; Flagship VentureLabs VI Manager LLC

AFEYAN NOUBAR; Flagship Pioneering, LLC; Flagship Ventures Fund V, L.P.; Flagship Ventures Opportunities Fund I, L.P.; Flagship Ventures Fund V General Partner LLC; Flagship Pioneering Special Opportunities Fund II General Partner LLC; Flagship Pioneering Special Opportunities Fund II, L.P.; Flagship Pioneering Fund VII, L.P.; Flagship Pioneering Fund VII General Partner LLC; Flagship Ventures Opportunities Fund I General Partner LLC

Flagship Pioneering Inc.

Flagship Pioneering Inc.

AFEYAN NOUBAR