22nd Century Group, Inc.

Regulation FD Disclosure

Beneficial ownership report for a passive holder of more than 5% (Schedule 13G)

Beneficial ownership report for a passive holder of more than 5% (Schedule 13G)

Beneficial ownership report for a passive holder of more than 5% (Schedule 13G)

General form for quarterly reports under Section 13 or 15(d)

Beneficial ownership report for a passive holder of more than 5% (Schedule 13G) (amendment)

Registration statement under Securities Act of 1933 to be offered to employees pursuant to certain plans

Prospectus Supplement for Primary Offering

Results of Operations and Financial Condition

Submission of Matters to a Vote of Security Holders

Termination of a Material Definitive Agreement

Prospectus Supplement for Primary Offering

Notice of Effectiveness

Definitive Proxy Statement

Preliminary Proxy Statement

Registration statement under Securities Act of 1933

Submission of Matters to a Vote of Security Holders

Entry into a Material Definitive Agreement

Entry into a Material Definitive Agreement

General form for quarterly reports under Section 13 or 15(d)

Results of Operations and Financial Condition

Entry into a Material Definitive Agreement

Prospectus Supplement for Primary Offering

Definitive Proxy Statement

Prospectus Supplement for Primary Offering

Prospectus Supplement for Primary Offering

Notice of Effectiveness

Correspondence with the SEC

Letter from the SEC

Registration statement under Securities Act of 1933

Registration statement under Securities Act of 1933 to be offered to employees pursuant to certain plans

Annual report pursuant to Section 13 or 15(d)

Results of Operations and Financial Condition

Prospectus Supplement for Primary Offering

Entry into a Material Definitive Agreement

Results of Operations and Financial Condition

Beneficial ownership report for a passive holder of more than 5% (Schedule 13G)

Beneficial ownership report for a passive holder of more than 5% (Schedule 13G) (amendment)

Beneficial ownership report for a passive holder of more than 5% (Schedule 13G) (amendment)

Beneficial ownership report for a passive holder of more than 5% (Schedule 13G) (amendment)

Material Modifications to Rights of Security Holders

Definitive Proxy Statement

Preliminary Proxy Statement

Entry into a Material Definitive Agreement

General form for quarterly reports under Section 13 or 15(d)

Entry into a Material Definitive Agreement

Prospectus Supplement for Primary Offering

Other Events

Termination of a Material Definitive Agreement

Changes in Registrant's Certifying Accountant

Prospectus Supplement for Primary Offering

Entry into a Material Definitive Agreement

Registration statement under Securities Act of 1933 to be offered to employees pursuant to certain plans

General form for quarterly reports under Section 13 or 15(d)

Results of Operations and Financial Condition

Beneficial ownership report for a passive holder of more than 5% (Schedule 13G) (amendment)

Beneficial ownership report for a passive holder of more than 5% (Schedule 13G) (amendment)

Prospectus Supplement for Primary Offering

Notice of Effectiveness

Correspondence with the SEC

Letter from the SEC

Registration statement under Securities Act of 1933

Letter from the SEC

No description available

Definitive Proxy Statement

Correspondence with the SEC

Letter from the SEC

Correspondence with the SEC

No description available

Letter from the SEC

Preliminary Proxy Statement

Prospectus Supplement for Primary Offering

Notice of Effectiveness

Correspondence with the SEC

Letter from the SEC

General form for quarterly reports under Section 13 or 15(d)

Annual report pursuant to Section 13 or 15(d) (amendment)

Annual report pursuant to Section 13 or 15(d)

Correspondence with the SEC

Correspondence with the SEC

Letter from the SEC

General form for quarterly reports under Section 13 or 15(d)

Letter from the SEC

Correspondence with the SEC

Definitive Proxy Statement

Preliminary Proxy Statement

Correspondence with the SEC

Letter from the SEC

No description available

General form for quarterly reports under Section 13 or 15(d)

No description available

General form for quarterly reports under Section 13 or 15(d)

Definitive Proxy Statement

Preliminary Proxy Statement

Annual report pursuant to Section 13 or 15(d)

Additional Information for Proxy Statement/ Votes

Definitive Proxy Statement

Preliminary Proxy Statement

General form for quarterly reports under Section 13 or 15(d)

Definitive Proxy Statement

Preliminary Proxy Statement

General form for quarterly reports under Section 13 or 15(d)

General form for quarterly reports under Section 13 or 15(d)

Definitive Proxy Statement

Preliminary Proxy Statement

Annual report pursuant to Section 13 or 15(d) (amendment)

Annual report pursuant to Section 13 or 15(d)

General form for quarterly reports under Section 13 or 15(d)

General form for quarterly reports under Section 13 or 15(d)

General form for quarterly reports under Section 13 or 15(d)

Arno Andrew

Staffeldt Jonathan

MANFREDONIA ROBERT P

Marion Arvil S.

SALHANY LUCILLE S

Otto Daniel A

FIRESTONE LAWRENCE

KEYS DAVID N

KEYS DAVID N

KEYS DAVID N