PACIFIC BIOSCIENCES OF CALIFORNIA, INC.

Beneficial ownership report for a passive holder of more than 5% (Schedule 13G) (amendment)

Registration statement under Securities Act of 1933 to be offered to employees pursuant to certain plans

General form for quarterly reports under Section 13 or 15(d)

Results of Operations and Financial Condition

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers: Compensatory Arrangements of Certain Officers

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers: Compensatory Arrangements of Certain Officers

Specialized Disclosure Report

Additional Information for Proxy Statement/ Votes

General form for quarterly reports under Section 13 or 15(d)

Results of Operations and Financial Condition

Annual Report Scanned (Paper)

Additional Information for Proxy Statement/ Votes

Definitive Proxy Statement

Beneficial ownership report for a passive holder of more than 5% (Schedule 13G) (amendment)

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers: Compensatory Arrangements of Certain Officers

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers: Compensatory Arrangements of Certain Officers

Annual report pursuant to Section 13 or 15(d)

Registration statement under Securities Act of 1933 to be offered to employees pursuant to certain plans

Automatic Shelf Registration

Results of Operations and Financial Condition

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers: Compensatory Arrangements of Certain Officers

Entry into a Material Definitive Agreement

Results of Operations and Financial Condition

General form for quarterly reports under Section 13 or 15(d)

Results of Operations and Financial Condition

General form for quarterly reports under Section 13 or 15(d)

Results of Operations and Financial Condition

Registration statement under Securities Act of 1933 to be offered to employees pursuant to certain plans

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers: Compensatory Arrangements of Certain Officers

Specialized Disclosure Report

Additional Information for Proxy Statement/ Votes

General form for quarterly reports under Section 13 or 15(d)

Results of Operations and Financial Condition

Annual Report Scanned (Paper)

Definitive Proxy Statement

Additional Information for Proxy Statement/ Votes

Results of Operations and Financial Condition

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers: Compensatory Arrangements of Certain Officers

Annual report pursuant to Section 13 or 15(d)

Registration statement under Securities Act of 1933 to be offered to employees pursuant to certain plans

Entry into a Material Definitive Agreement

Results of Operations and Financial Condition

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers: Compensatory Arrangements of Certain Officers

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers: Compensatory Arrangements of Certain Officers

Post-effective amendment to an automatic shelf registration statement

General form for quarterly reports under Section 13 or 15(d)

General form for quarterly reports under Section 13 or 15(d)

Registration statement under Securities Act of 1933 to be offered to employees pursuant to certain plans

Specialized Disclosure Report

Additional Information for Proxy Statement/ Votes

General form for quarterly reports under Section 13 or 15(d)

Automatic Shelf Registration

Annual Report Scanned (Paper)

Definitive Proxy Statement

Additional Information for Proxy Statement/ Votes

Preliminary Proxy Statement

Post-effective amendment to an automatic shelf registration statement

Post-effective amendment to an automatic shelf registration statement

Post-effective amendment to an automatic shelf registration statement

Registration statement under Securities Act of 1933 to be offered to employees pursuant to certain plans

Annual report pursuant to Section 13 or 15(d)

General form for quarterly reports under Section 13 or 15(d)

06b

Automatic Shelf Registration

06b

General form for quarterly reports under Section 13 or 15(d)

Specialized Disclosure Report

General form for quarterly reports under Section 13 or 15(d)

Annual Report Scanned (Paper)

Additional Information for Proxy Statement/ Votes

Definitive Proxy Statement

Preliminary Proxy Statement

Annual report pursuant to Section 13 or 15(d)

Registration statement under Securities Act of 1933 to be offered to employees pursuant to certain plans

Prospectus Supplement for Primary Offering

Prospectus Supplement for Primary Offering

General form for quarterly reports under Section 13 or 15(d)

General form for quarterly reports under Section 13 or 15(d)

Notice of Effectiveness

Post-effective amendment to a registration statement

Registration statement under Securities Act of 1933 to be offered to employees pursuant to certain plans

Specialized Disclosure Report

Additional Information for Proxy Statement/ Votes

Additional Information for Proxy Statement/ Votes

General form for quarterly reports under Section 13 or 15(d)

Additional Information for Proxy Statement/ Votes

Definitive Proxy Statement

Additional Information for Proxy Statement/ Votes

Annual report pursuant to Section 13 or 15(d)

Registration statement under Securities Act of 1933 to be offered to employees pursuant to certain plans

Registration statement under Securities Act of 1933 to be offered to employees pursuant to certain plans

General form for quarterly reports under Section 13 or 15(d)

No description available

Registration statement under Securities Act of 1933 to be offered to employees pursuant to certain plans

Letter from the SEC

Specialized Disclosure Report

Correspondence with the SEC

Additional Information for Proxy Statement/ Votes

Definitive Proxy Statement

Letter from the SEC

Correspondence with the SEC

Correspondence with the SEC

Van Oene Mark

Van Oene Mark

Van Oene Mark

MOHR MARSHALL

ORDONEZ KATHY

MILLIGAN JOHN F

Ericson William W.

LIVINGSTON RANDALL S

Valantine Hannah

Smith Christopher M

Gibson Christopher

Gibson Christopher

Gibson James R II

Gibson James R II

Gibson Christopher

Gibson Christopher

Van Oene Mark

Farmer Michele