TANG CAPITAL MANAGEMENT LLC

Annual Report of Proxy Voting Record of Registered Management Investment Company

Beneficial ownership report for a passive holder of more than 5% (Schedule 13G)

Beneficial ownership report for a passive holder of more than 5% (Schedule 13G)

Beneficial ownership report for a passive holder of more than 5% (Schedule 13G) (amendment)

Beneficial ownership report for a passive holder of more than 5% (Schedule 13G) (amendment)

Beneficial ownership report for a passive holder of more than 5% (Schedule 13G) (amendment)

Report of Holders of Securities

Beneficial ownership report for a passive holder of more than 5% (Schedule 13G) (amendment)

Beneficial ownership report for a holder of more than 5% (Schedule 13D) (amendment)

Beneficial ownership report for a holder of more than 5% (Schedule 13D) (amendment)

Beneficial ownership report for a passive holder of more than 5% (Schedule 13G) (amendment)

Beneficial ownership report for a passive holder of more than 5% (Schedule 13G) (amendment)

Annual Report of Proxy Voting Record of Registered Management Investment Company

Annual Report of Proxy Voting Record of Registered Management Investment Company

TANG KEVIN; TANG CAPITAL MANAGEMENT LLC

TANG KEVIN; TANG CAPITAL MANAGEMENT LLC

TANG KEVIN; TANG CAPITAL MANAGEMENT LLC

TANG KEVIN; TANG CAPITAL MANAGEMENT LLC

TANG KEVIN; TANG CAPITAL MANAGEMENT LLC

TANG KEVIN; TANG CAPITAL MANAGEMENT LLC

TANG KEVIN; TANG CAPITAL MANAGEMENT LLC

TANG KEVIN; TANG CAPITAL MANAGEMENT LLC

TANG KEVIN; TANG CAPITAL MANAGEMENT LLC