Institutional HoldersBeta
Who holds a company, from every 13F filed for the quarter, one row per filer exactly as filed, against the latest share count the company reported.
Share classes (cover page of the 10-Q filed 2026-08-07, as of 2026-08-04)
| Class | Listed | Shares outstanding | Held by 13F filers | % of class | Holders | CUSIP |
|---|---|---|---|---|---|---|
| Common stock | AGEN · NASDAQ | 45,020,407 | 14,249,216 | 31.7% | 102 | 00847G804 |
Each class is compared with its own share count; classes are not added together. A class that is not exchange-listed cannot be held by 13F filers.
Top holders (102 of 102 · 00847G804)
change vs 2026-03-31Exited since 2026-03-31 (16 filers; largest 16 shown)
| Walleye Capital LLC | −120,565 |
| 683 Capital Management, LLC | −114,336 |
| CITADEL ADVISORS LLC | −52,004 |
| MILLENNIUM MANAGEMENT LLC | −43,409 |
| OMERS ADMINISTRATION Corp | −34,700 |
| Hudson Bay Capital Management LP | −33,543 |
| D. E. Shaw & Co., Inc. | −33,269 |
| AXQ CAPITAL, LP | −29,055 |
| TWO SIGMA SECURITIES, LLC | −17,744 |
| Redwood Family Wealth LLC | −14,140 |
| Squarepoint Ops LLC | −12,373 |
| Qube Research & Technologies Ltd | −10,474 |
| CWM, LLC | −820 |
| EverSource Wealth Advisors, LLC | −274 |
| Root Financial Partners, LLC | −25 |
| Advisory Services Network, LLC | −5 |
Large holders from 13D/13G (latest per reporting person, last 2 years)
Filed when a holder crosses 5% or changes materially, so often more current than the quarter-end 13F. Percentages are the filer's own, against the share count they used.
| Reporting person | Form | Filed | Event | Shares | % of class |
|---|---|---|---|---|---|
| BlackRock, Inc. | SCHEDULE 13G | 2026-07-27 | 2026-06-30 | 2,513,893 | 6% |
| Peter Kolchinsky | SCHEDULE 13G | 2026-07-20 | 2026-07-13 | 4,344,772 | 9.9% |
| Rajeev Shah | SCHEDULE 13G | 2026-07-20 | 2026-07-13 | 4,344,772 | 9.9% |
| RA Capital Management, L.P. | SCHEDULE 13G | 2026-07-20 | 2026-07-13 | 4,344,772 | 9.9% |
| RA Capital Healthcare Fund, L.P. | SCHEDULE 13G | 2026-07-20 | 2026-07-13 | 4,344,772 | 9.9% |
| Invus Public Equities Advisors, LLC | SCHEDULE 13G | 2026-07-17 | 2026-07-13 | 3,971,647 | 8.8% |
| Invus Public Equities, L.P. | SCHEDULE 13G | 2026-07-17 | 2026-07-13 | 3,971,647 | 8.8% |
| Avicenna Life Sci Master Fund LP | SCHEDULE 13G | 2026-07-17 | 2026-07-13 | 562,108 | 1.3% |
| Invus Global Management, LLC | SCHEDULE 13G | 2026-07-17 | 2026-07-13 | 3,971,647 | 8.8% |
| Avicenna Life Sci Master GP LLC | SCHEDULE 13G | 2026-07-17 | 2026-07-13 | 562,108 | 1.3% |
| Raymond Debbane | SCHEDULE 13G | 2026-07-17 | 2026-07-13 | 4,533,755 | 9.99% |
| Siren, L.L.C. | SCHEDULE 13G | 2026-07-17 | 2026-07-13 | 3,971,647 | 8.8% |
| Ulys, L.L.C. | SCHEDULE 13G | 2026-07-17 | 2026-07-13 | 562,108 | 1.3% |
| The Vanguard Group | SCHEDULE 13G/A | 2026-03-26 | 2026-03-13 | 0 | 0% |
| ZYDUS LIFESCIENCES LTD | SCHEDULE 13D | 2026-01-23 | 2026-01-15 | 2,133,333 | 5.9% |
| ZYNEXT VENTURES PTE LTD | SCHEDULE 13D | 2026-01-23 | 2026-01-15 | 2,133,333 | 5.9% |
| ZYNEXT VENTURES USA LLC | SCHEDULE 13D | 2026-01-23 | 2026-01-15 | 2,133,333 | 5.9% |
Source: SEC Form 13F-HR information tables for the quarter ending 2026-06-30 (filed within 45 days of quarter end; amendments applied; values normalised to dollars), the share count from the company's latest 10-K/10-Q XBRL cover page, and Schedule 13D/13G filings. Each row is a legal 13F filer as filed — related entities (e.g. Vanguard's advisers) are not merged. Retail brokerage accounts are not reported on 13F, so the remainder is mostly retail and insiders.