Institutional HoldersBeta
Who holds a company, from every 13F filed for the quarter, one row per filer exactly as filed, against the latest share count the company reported.
Held by 13F filers
648,623,783
selection includes debt or preferreds — no % of shares outstanding
Holders
52
+1 vs 2026-03-31 · 13 new, 12 exited
Value
$758.2M
shares +7.6% vs prior quarter
Share classes (cover page of the 10-Q filed 2026-08-04, as of 2026-07-30)
| Class | Listed | Shares outstanding | Held by 13F filers | % of class | Holders | CUSIP |
|---|---|---|---|---|---|---|
| Common stock | ARWR · NASDAQ | 141,254,467 | 119,539,570 | 84.6% | 502 | 04280A100 |
Each class is compared with its own share count; classes are not added together. A class that is not exchange-listed cannot be held by 13F filers.
Top holders (52 of 52 · 04280AAC4)
change vs 2026-03-31| # | Filer | Shares / principal | % of class | Value | Change |
|---|---|---|---|---|---|
| 1 | DEERFIELD MANAGEMENT COMPANY, L.P. | 200,000,000 | — | $240.5M | — |
| 2 | CAMDEN ASSET MANAGEMENT L P /CA | 64,283,000 | — | $76.7M | +18,783,000 (+41.3%) |
| 3 | LMR Partners LLP | 40,000,000 | — | $47.8M | +5,000,000 (+14.3%) |
| 4 | Linden Advisors LP | 34,889,000 | — | $41.8M | -57,506,000 (-62.2%) |
| 5 | UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 29,000,000 | — | $34.6M | NEW |
| 6 | READYSTATE ASSET MANAGEMENT LP | 25,000,000 | — | $29.9M | — |
| 7 | LAZARD ASSET MANAGEMENT LLC | 24,898,000 | — | $298K | +16,092,000 (+182.7%) |
| 8 | Calamos Advisors LLC | 22,199,000 | — | $26.8M | -540,000 (-2.4%) |
| 9 | MacKay Shields LLC | 20,457,000 | — | $24.5M | +17,457,000 (+581.9%) |
| 10 | DeepCurrents Investment Group LLC | 19,000,000 | — | $22.8M | NEW |
| 11 | STATE STREET CORP | 18,450,000 | — | $22.1M | +4,750,000 (+34.7%) |
| 12 | Context Capital Management, LLC | 18,400,000 | — | $22.0M | +3,500,000 (+23.5%) |
| 13 | ADVENT CAPITAL MANAGEMENT /DE/ | 17,840,000 | — | $21.4M | NEW |
| 14 | DZ BANK AG Deutsche Zentral Genossenschafts Bank, Frankfurt am Main | 12,150,000 | — | $14.6M | +11,150,000 (+1115.0%) |
| 15 | OAKTREE CAPITAL MANAGEMENT LP | 9,146,000 | — | $11.0M | -1,909,000 (-17.3%) |
| 16 | Balyasny Asset Management L.P. | 8,500,000 | — | $10.2M | NEW |
| 17 | Lombard Odier Asset Management (Europe) Ltd | 8,452,000 | — | $10.1M | NEW |
| 18 | LORD, ABBETT & CO. LLC | 7,265,000 | — | $8.7M | NEW |
| 19 | FMR LLC | 7,140,000 | — | $8.5M | -40,000 (-0.6%) |
| 20 | CITADEL ADVISORS LLC | 7,100,000 | — | $8.5M | NEW |
| 21 | SSI INVESTMENT MANAGEMENT LLC | 6,587,000 | — | $7.9M | — |
| 22 | SHENKMAN CAPITAL MANAGEMENT INC | 5,752,000 | — | $7.0M | -2,953,000 (-33.9%) |
| 23 | Weiss Asset Management LP | 5,000,000 | — | $6.0M | NEW |
| 24 | STATE OF WISCONSIN INVESTMENT BOARD | 4,000,000 | — | $4.8M | +1,000,000 (+33.3%) |
| 25 | MORGAN STANLEY | 3,797,000 | — | $4.5M | +3,102,000 (+446.3%) |
| 26 | MILLENNIUM MANAGEMENT LLC | 3,125,000 | — | $3.8M | -250,000 (-7.4%) |
| 27 | Amundi | 3,100,000 | — | $3.7M | — |
| 28 | TORONTO DOMINION BANK | 3,056,000 | — | $3.7M | +2,103,000 (+220.7%) |
| 29 | BANK OF AMERICA CORP /DE/ | 2,680,000 | — | $3.2M | +2,180,000 (+436.0%) |
| 30 | AGF MANAGEMENT LTD | 2,250,000 | — | $2.7M | +1,000,000 (+80.0%) |
| 31 | TENOR CAPITAL MANAGEMENT Co., L.P. | 2,000,000 | — | $2.4M | — |
| 32 | Invesco Ltd. | 2,000,000 | — | $2.4M | -1,250,000 (-38.5%) |
| 33 | Man Group plc | 1,805,000 | — | $2.1M | +855,000 (+90.0%) |
| 34 | Acasta Partners UK LLP | 1,500,000 | — | $1.8M | +1,100,000 (+275.0%) |
| 35 | BNP PARIBAS FINANCIAL MARKETS | 1,386,000 | — | $1.7M | -12,593,000 (-90.1%) |
| 36 | RWC Asset Management LLP | 1,307,000 | — | $1.6M | -72,000 (-5.2%) |
| 37 | Bank of New York Mellon Corp | 1,115,000 | — | $1.3M | -100,000 (-8.2%) |
| 38 | GROUPAMA ASSET MANAGMENT | 1,000,000 | — | $1.2M | — |
| 39 | WELLS FARGO & COMPANY/MN | 885,000 | — | $1.1M | +25,000 (+2.9%) |
| 40 | Kohlberg Kravis Roberts & Co. L.P. | 800,000 | — | $958K | — |
| 41 | Central Pacific Bank - Trust Division | 342,000 | — | $408K | NEW |
| 42 | SEI INVESTMENTS CO | 200,000 | — | $239K | +168,000 (+525.0%) |
| 43 | Russell Investments Group, Ltd. | 182,000 | — | $219K | NEW |
| 44 | UBS Group AG | 152,000 | — | $181K | -4,047,000 (-96.4%) |
| 45 | OPPENHEIMER ASSET MANAGEMENT INC. | 103,000 | — | $123K | NEW |
| 46 | Ares Systematic Credit Ltd | 100,000 | — | $120K | -900,000 (-90.0%) |
| 47 | Calamos Wealth Management LLC | 87,000 | — | $105K | NEW |
| 48 | LOOMIS SAYLES & CO L P | 65,633 | — | $5.3M | -106,541 (-61.9%) |
| 49 | STEPHENS INC /AR/ | 33,000 | — | $39K | NEW |
| 50 | SG Americas Securities, LLC | 29,150 | — | $3.5M | +22,250 (+322.5%) |
| 51 | ADAR1 Capital Management, LLC | 10,000 | — | $1.2M | — |
| 52 | CITIGROUP INC | 6,000 | — | $7K | -3,510,000 (-99.8%) |
Exited since 2026-03-31 (12 filers; largest 12 shown)
| Jump Financial, LLC | −18,702,000 |
| Polar Asset Management Partners Inc. | −10,000,000 |
| Point72 Asset Management, L.P. | −7,775,000 |
| JPMORGAN CHASE & CO | −6,523,000 |
| VOYA INVESTMENT MANAGEMENT LLC | −5,265,000 |
| GOLDMAN SACHS GROUP INC | −3,000,000 |
| BRAIDWELL LP | −2,250,000 |
| GABELLI FUNDS LLC | −2,090,000 |
| FRANKLIN RESOURCES INC | −1,650,000 |
| JANE STREET GROUP, LLC | −1,500,000 |
| Davidson Kempner Capital Management LP | −1,000,000 |
| NOMURA HOLDINGS INC | −13,954 |
Large holders from 13D/13G (latest per reporting person, last 2 years)
Filed when a holder crosses 5% or changes materially, so often more current than the quarter-end 13F. Percentages are the filer's own, against the share count they used.
| Reporting person | Form | Filed | Event | Shares | % of class |
|---|---|---|---|---|---|
| Avoro Capital Advisors LLC | SCHEDULE 13G/A | 2026-08-14 | 2026-06-30 | 13,823,383 | 9.64% |
| Behzad Aghazadeh | SCHEDULE 13G/A | 2026-08-14 | 2026-06-30 | 13,823,383 | 9.64% |
| Vanguard Portfolio Management | SCHEDULE 13G/A | 2026-07-31 | 2026-06-30 | 6,384,903 | 4.53% |
| BlackRock, Inc. | SCHEDULE 13G/A | 2026-07-27 | 2026-06-30 | 14,232,545 | 10.1% |
| Abigail P. Johnson | SCHEDULE 13G | 2026-05-06 | 2026-03-31 | 7,349,106.75 | 5.2% |
| FMR LLC | SCHEDULE 13G | 2026-05-06 | 2026-03-31 | 7,349,106.75 | 5.2% |
| Vanguard Capital Management | SCHEDULE 13G | 2026-04-29 | 2026-03-31 | 7,081,293 | 5.05% |
| The Vanguard Group | SCHEDULE 13G/A | 2026-03-26 | 2026-03-13 | 0 | 0% |
| Sarepta Therapeutics, Inc. | SCHEDULE 13D/A | 2025-08-15 | 2025-08-13 | 0 | 0% |
| Sarepta Therapeutics Investments, Inc. | SCHEDULE 13D/A | 2025-08-15 | 2025-08-13 | 0 | 0% |
| STATE STREET CORPORATION | SCHEDULE 13G | 2025-08-11 | 2025-06-30 | 6,371,056 | 4.6% |
Source: SEC Form 13F-HR information tables for the quarter ending 2026-06-30 (filed within 45 days of quarter end; amendments applied; values normalised to dollars), the share count from the company's latest 10-K/10-Q XBRL cover page, and Schedule 13D/13G filings. Each row is a legal 13F filer as filed — related entities (e.g. Vanguard's advisers) are not merged. Retail brokerage accounts are not reported on 13F, so the remainder is mostly retail and insiders.