Exhibit 5.2
March 6, 2009
Eli Lilly and Company
Lilly Corporate Center
Indianapolis, Indiana 46285
Lilly Corporate Center
Indianapolis, Indiana 46285
Ladies and Gentlemen:
I am the Assistant Secretary and Associate General Counsel of Eli Lilly and Company, an Indiana
corporation (the Company). I am rendering this opinion in connection with the proposed
issuance, by the Company, of $1,000,000,000 principal amount of the Companys 3.550% Notes due
2012, $1,000,000,000 principal amount of the Companys 4.200% Notes due 2014 and $400,000,000
principal amount of the Companys 5.950% Notes due 2037 (collectively, the Debt
Securities) pursuant to the prospectus supplement dated March 3, 2009 (the Prospectus
Supplement), supplementing the prospectus dated March 3, 2009 (the Base Prospectus)
that forms part of the Companys Registration Statement on Form S-3 (File No. 333-141075) (the
Registration Statement) filed with the U.S. Securities and Exchange Commission (the
Commission) on March 5, 2007 under the Securities Act of 1933, as amended (the
Securities Act), and pursuant to an Indenture, dated February 1, 1991 (the
Indenture), between the Company and Deutsche Bank Trust Company Americas, as successor
trustee to Citibank, N.A., as original trustee, and the Underwriting Agreement (the
Underwriting Agreement), dated March 3, 2009, between the Company, and Credit Suisse
Securities (USA) LLC, Deutsche Bank Securities Inc. and UBS Securities LLC, as representatives of
the several underwriters named therein. As used in this letter, the term Prospectus means the
Prospectus Supplement and the Base Prospectus, including the documents incorporated or deemed to be
incorporated by reference therein pursuant to Item 12 of Form S-3 under the Securities Act.
I have examined and am familiar with originals, or copies certified or otherwise identified to my
satisfaction, of such documents, corporate records, certificates of officers of the Company and of
public officials and such other instruments as I have deemed necessary or appropriate as a basis
for the opinions expressed below, including the Registration Statement, the Prospectus, the
Companys Amended Articles of Incorporation, the Companys By-Laws, the Indenture, the Debt
Securities and the Underwriting Agreement.
For purposes of the opinions expressed below, I have assumed, without independent investigation,
that (i) the Indenture and the Underwriting Agreement have been duly authorized, executed and
delivered by the parties thereto other than the Company and constitute valid and binding
obligations of the parties thereto other than the Company, enforceable against each of them in
accordance with their respective terms; and (ii) the certificates representing the Debt Securities
will conform as to form to the form of global notes examined by me. I have also assumed, without
independent investigation, the genuineness and authenticity of all documents submitted to me as
originals, the conformity to originals of all documents submitted to me as
copies thereof and the due execution and delivery of all documents where due execution and delivery
are prerequisites to the effectiveness thereof.
On the basis of, and in reliance on, the foregoing and subject to the assumptions, exceptions,
qualifications and limitations contained herein, I am of the opinion that:
| 1. | The Company is a corporation duly organized and validly existing under the laws of the State of Indiana. | |
| 2. | Each of the Indenture and the Underwriting Agreement has been duly and validly authorized, executed and delivered by the Company. | |
| 3. | The Company has duly authorized the issuance of the Debt Securities, and the Company has full corporate power and authority to issue the Debt Securities and to perform its obligations under the Debt Securities, the Indenture and the Underwriting Agreement. |
I am a member of the bar of the State of Indiana and express no opinion as to the laws of any other
jurisdiction.
I hereby consent that Sidley Austin llp may rely upon this opinion as if it were addressed
to them.
The foregoing opinion is rendered as of the date hereof, and I assume no obligation to update such
opinion to reflect any facts or circumstances which may hereafter come to my attention or any
changes in the law which may hereafter occur.
I hereby consent to the incorporation by reference of this opinion into the Registration Statement
and to the reference to my name under the heading Legal Matters in the Prospectus. In giving
such consent, I do not admit that I come within the category of persons whose consent is required
under Section 7 of the Securities Act or the rules and regulations of the Commission.
Yours truly,
| /s/ Bronwen Mantlo | ||||
| Bronwen Mantlo | ||||
| Assistant Secretary and Associate General Counsel | ||||
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