Institutional HoldersBeta

Who holds a company, from every 13F filed for the quarter, one row per filer exactly as filed, against the latest share count the company reported.

Definium Therapeutics, Inc.

CIK 0001813814DFTX· quarter ending 2026-06-30

Shares outstanding

134,366,950

as of 2026-07-30 · 10-Q cover page, filed 2026-08-06

Held by 13F filers

114,822,299

85.5% of shares outstanding

Holders

361

+115 vs 2026-03-31 · 149 new, 34 exited

Value

$5.4B

shares +46.5% vs prior quarter

Share classes (cover page of the 10-Q filed 2026-08-06, as of 2026-07-30)

Class	Listed	Shares outstanding	Held by 13F filers	% of class	Holders	CUSIP
Common stock	DFTX · NASDAQ	134,366,950	114,822,299	85.5%	361	24477V105

Each class is compared with its own share count; classes are not added together. A class that is not exchange-listed cannot be held by 13F filers.

Securities (CUSIPs held in 13F this quarter)

tick to combine

Count	CUSIP	Class (as filers write it)	Holders	Shares held	Class shares	% of class	Value	Options	Mapped via
	24477V105	COM SHS	361	114,822,299	134,366,950	85.5%	$5.4B	15 call / 12 put	13DG	holders →
	60255C109	COMMON STOCK-FOnot common	1	1	—	—	$1	—	prefix	holders →

Totals combine the ticked CUSIPs and update as you tick: common-stock classes by default; preferreds, notes, warrants and depositary shares are listed but not counted. "holders →" shows a single CUSIP on its own. Bonds are held as a principal amount, not shares. Options positions are never counted as holdings. 1 further CUSIPs map to this company (mostly bonds) but no 13F filer held them this quarter.

Top holders (250 of 361 · 24477V105)

change vs 2026-03-31

#	Filer	Shares	% of class	Value	Change
1	BlackRock, Inc.	11,232,834	8.36%	$528.4M	+2,752,604 (+32.5%)
2	Avoro Capital Advisors LLC	7,188,888	5.35%	$338.2M	+2,188,888 (+43.8%)
3	Driehaus Capital Management LLC	6,845,276	5.09%	$322.0M	+933,387 (+15.8%)
4	Jupiter Topco LLC	5,615,645	4.18%	$264.0M	NEW
5	Capital World Investors	5,367,723	3.99%	$252.5M	NEW
6	FMR LLC	4,752,921	3.54%	$223.6M	+2,943,311 (+162.6%)
7	PRICE T ROWE ASSOCIATES INC /MD/	4,652,032	3.46%	$218.8M	+4,582,031 (+6545.7%)
8	GEODE CAPITAL MANAGEMENT, LLC	3,644,813	2.71%	$171.5M	+1,149,414 (+46.1%)
9	STATE STREET CORP	3,065,390	2.28%	$144.2M	+593,517 (+24.0%)
10	Capital International Investors	2,963,410	2.21%	$139.4M	NEW
11	Octagon Capital Advisors LP	2,950,000	2.20%	$138.8M	+510,000 (+20.9%)
12	WELLINGTON MANAGEMENT GROUP LLP	2,949,734	2.20%	$138.8M	+1,644,985 (+126.1%)
13	Deep Track Capital, LP	2,750,000	2.05%	$129.4M	-250,000 (-8.3%)
14	Commodore Capital LP	2,000,000	1.49%	$94.1M	—
15	ALLIANCEBERNSTEIN L.P.	1,803,287	1.34%	$34.1M	+1,711,584 (+1866.4%)
16	GOLDMAN SACHS GROUP INC	1,800,852	1.34%	$84.7M	+125,441 (+7.5%)
17	CITADEL ADVISORS LLC	1,688,587	1.26%	$79.4M	+355,145 (+26.6%)
18	VANGUARD PORTFOLIO MANAGEMENT LLC	1,648,426	1.23%	$77.5M	+775,761 (+88.9%)
19	RA CAPITAL MANAGEMENT, L.P.	1,500,000	1.12%	$70.6M	NEW
20	VANGUARD CAPITAL MANAGEMENT LLC	1,486,454	1.11%	$69.9M	+389,476 (+35.5%)
21	Siren, L.L.C.	1,419,493	1.06%	$66.8M	+500,000 (+54.4%)
22	MARSHALL WACE, LLP	1,298,946	0.97%	$61.1M	+98,121 (+8.2%)
23	NORTHERN TRUST CORP	1,169,238	0.87%	$55.0M	+370,251 (+46.3%)
24	AMERIPRISE FINANCIAL INC	1,148,363	0.85%	$54.0M	+181,755 (+18.8%)
25	Nuveen, LLC	1,105,314	0.82%	$52.0M	+407,184 (+58.3%)
26	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	1,083,576	0.81%	$51.0M	+274,861 (+34.0%)
27	Woodline Partners LP	1,003,641	0.75%	$47.2M	+250,849 (+33.3%)
28	ADAGE CAPITAL PARTNERS GP, L.L.C.	1,000,000	0.74%	$47.0M	-150,000 (-13.0%)
29	Boxer Capital Management, LLC	998,500	0.74%	$47.0M	+400,000 (+66.8%)
30	TWO SIGMA INVESTMENTS, LP	921,818	0.69%	$43.4M	-279,792 (-23.3%)
31	Balyasny Asset Management L.P.	897,658	0.67%	$42.2M	-376,563 (-29.6%)
32	VANGUARD FIDUCIARY TRUST CO	827,693	0.62%	$38.9M	+251,756 (+43.7%)
33	Holocene Advisors, LP	796,574	0.59%	$37.5M	-295,393 (-27.1%)
34	AWM Investment Company, Inc.	784,800	0.58%	$36.9M	-292,093 (-27.1%)
35	Bank of New York Mellon Corp	777,271	0.58%	$36.6M	+24,349 (+3.2%)
36	Polar Capital Holdings Plc	777,253	0.58%	$36.6M	NEW
37	EVENTIDE ASSET MANAGEMENT, LLC	710,000	0.53%	$33.4M	+23,838 (+3.5%)
38	NEUBERGER BERMAN GROUP LLC	687,539	0.51%	$32.3M	+554,170 (+415.5%)
39	Qube Research & Technologies Ltd	682,901	0.51%	$32.1M	+256,846 (+60.3%)
40	Candriam S.C.A.	614,425	0.46%	$28.9M	-679,204 (-52.5%)
41	ArrowMark Colorado Holdings LLC	564,069	0.42%	$26.5M	-1,030,648 (-64.6%)
42	Catalio Capital Management, LP	562,672	0.42%	$26.5M	-475,312 (-45.8%)
43	Blackstone Inc.	561,612	0.42%	$26.4M	+52,944 (+10.4%)
44	Integral Health Asset Management, LLC	550,000	0.41%	$25.9M	+150,000 (+37.5%)
45	BAMCO INC /NY/	520,108	0.39%	$24.5M	NEW
46	UBS Group AG	499,467	0.37%	$23.5M	+5,490 (+1.1%)
47	FRANKLIN RESOURCES INC	486,219	0.36%	$22.9M	NEW
48	Point72 Asset Management, L.P.	483,980	0.36%	$22.8M	+308,490 (+175.8%)
49	Ensign Peak Advisors, Inc	466,106	0.35%	$21.9M	-80,677 (-14.8%)
50	MORGAN STANLEY	454,912	0.34%	$21.4M	+16,339 (+3.7%)
51	GREAT POINT PARTNERS LLC	425,000	0.32%	$20.0M	NEW
52	Cormorant Asset Management, LP	400,000	0.30%	$18.8M	NEW
53	SILVERARC CAPITAL MANAGEMENT, LLC	400,000	0.30%	$18.8M	NEW
54	RTW INVESTMENTS, LP	400,000	0.30%	$18.8M	+100,000 (+33.3%)
55	ASSETMARK, INC	396,542	0.30%	$18.7M	NEW
56	ORBIMED ADVISORS LLC	365,400	0.27%	$17.2M	-438,600 (-54.6%)
57	Duquesne Family Office LLC	356,600	0.27%	$16.8M	NEW
58	D. E. Shaw & Co., Inc.	315,410	0.23%	$14.8M	+43,693 (+16.1%)
59	Tetragon Partners GP Ltd	286,990	0.21%	$13.5M	+86,996 (+43.5%)
60	MILLENNIUM MANAGEMENT LLC	266,076	0.20%	$12.5M	-580,820 (-68.6%)
61	JPMORGAN CHASE & CO	265,955	0.20%	$12.4M	+1,410 (+0.5%)
62	Sofinnova Investments, Inc.	255,903	0.19%	$12.0M	-88,263 (-25.6%)
63	PFM Health Sciences, LP	249,020	0.19%	$11.7M	+43,703 (+21.3%)
64	HighVista Strategies LLC	242,884	0.18%	$11.4M	+57,028 (+30.7%)
65	Trexquant Investment LP	233,199	0.17%	$11.0M	NEW
66	SEVEN GRAND MANAGERS, LLC	225,000	0.17%	$10.6M	—
67	Swiss National Bank	221,200	0.16%	$10.4M	+62,800 (+39.6%)
68	Eversept Partners, LP	217,185	0.16%	$10.2M	+56,462 (+35.1%)
69	UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC	211,183	0.16%	$9.9M	+208,770 (+8651.9%)
70	TD Asset Management Inc	209,460	0.16%	$9.9M	NEW
71	ROYCE & ASSOCIATES LP	208,551	0.16%	$9.8M	-25,500 (-10.9%)
72	SEB Asset Management AB	208,254	0.15%	$9.8M	NEW
73	SUPERSTRING CAPITAL MANAGEMENT LP	188,282	0.14%	$8.9M	-163,179 (-46.4%)
74	EMERALD ADVISERS, LLC	178,751	0.13%	$8.4M	NEW
75	Aberdeen Group plc	175,000	0.13%	$8.2M	NEW
76	BANK OF AMERICA CORP /DE/	164,575	0.12%	$7.7M	+6,230 (+3.9%)
77	Tri Locum Partners LP	162,996	0.12%	$7.7M	-206,592 (-55.9%)
78	RHUMBLINE ADVISERS	158,096	0.12%	$7.4M	+38,124 (+31.8%)
79	Brevan Howard Capital Management LP	156,812	0.12%	$7.4M	-54,676 (-25.9%)
80	Russell Investments Group, Ltd.	153,477	0.11%	$7.2M	+34,013 (+28.5%)
81	LMR Partners LLP	150,200	0.11%	$7.1M	NEW
82	Seven Fleet Capital Management LP	148,647	0.11%	$7.0M	+48,760 (+48.8%)
83	MANUFACTURERS LIFE INSURANCE COMPANY, THE	146,368	0.11%	$6.9M	+119,964 (+454.3%)
84	Rock Springs Capital Management LP	143,187	0.11%	$6.7M	NEW
85	DEUTSCHE BANK AG\	142,947	0.11%	$6.7M	-268,887 (-65.3%)
86	SummitTX Capital, L.P.	142,489	0.11%	$6.7M	NEW
87	STEMPOINT CAPITAL LP	137,124	0.10%	$6.5M	-513,842 (-78.9%)
88	AQR CAPITAL MANAGEMENT LLC	134,152	0.10%	$6.3M	+77,058 (+135.0%)
89	CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM	128,346	0.10%	$6.0M	NEW
90	BIT Capital GmbH	128,131	0.10%	$6.0M	-149,380 (-53.8%)
91	FRED ALGER MANAGEMENT, LLC	125,256	0.09%	$5.9M	+33,091 (+35.9%)
92	WELLS FARGO & COMPANY/MN	122,033	0.09%	$5.7M	+82,060 (+205.3%)
93	Atika Capital Management LLC	122,000	0.09%	$5.7M	NEW
94	AdvisorShares Investments LLC	121,381	0.09%	$5.7M	+30,080 (+32.9%)
95	EMERALD MUTUAL FUND ADVISERS TRUST	121,249	0.09%	$5.7M	NEW
96	Informed Momentum Co LLC	120,928	0.09%	$5.7M	NEW
97	Schonfeld Strategic Advisors LLC	119,610	0.09%	$5.6M	+109,198 (+1048.8%)
98	HSBC HOLDINGS PLC	117,482	0.09%	$5.5M	NEW
99	ALPS ADVISORS INC	110,388	0.08%	$5.2M	NEW
100	Data Collective IV GP, LLC	100,350	0.07%	$4.7M	—
101	ROYAL BANK OF CANADA	100,063	0.07%	$4.7M	+2,871 (+3.0%)
102	Burkehill Global Management, LP	100,000	0.07%	$4.7M	—
103	BNP PARIBAS FINANCIAL MARKETS	96,510	0.07%	$4.5M	+73,154 (+313.2%)
104	VOYA INVESTMENT MANAGEMENT LLC	95,166	0.07%	$4.5M	+78,782 (+480.8%)
105	KEYSTONE INVESTORS PTE LTD	95,100	0.07%	$4.5M	NEW
106	Invesco Ltd.	91,338	0.07%	$4.3M	+3,217 (+3.7%)
107	Pier Capital, LLC	88,598	0.07%	$4.2M	NEW
108	LPL Financial LLC	86,136	0.06%	$4.1M	+7,865 (+10.0%)
109	Squadron Capital Management LLC	85,000	0.06%	$4.0M	NEW
110	XTX Topco Ltd	84,393	0.06%	$4.0M	NEW
111	Shay Capital LLC	80,000	0.06%	$3.8M	NEW
112	Logos Global Management LP	80,000	0.06%	$3.8M	NEW
113	CITIGROUP INC	79,547	0.06%	$3.7M	+53,061 (+200.3%)
114	VANGUARD ASSET MANAGEMENT, Ltd	78,604	0.06%	$3.7M	+24,586 (+45.5%)
115	SECTORAL ASSET MANAGEMENT INC	78,310	0.06%	$3.7M	NEW
116	MetLife Investment Management, LLC	75,859	0.06%	$3.6M	+21,598 (+39.8%)
117	Legal & General Group Plc	74,004	0.06%	$3.5M	+14,205 (+23.8%)
118	Quantinno Capital Management LP	70,682	0.05%	$3.3M	+30,724 (+76.9%)
119	Rockefeller Capital Management L.P.	70,111	0.05%	$3.3M	+14,905 (+27.0%)
120	PLATINUM INVESTMENT MANAGEMENT LTD	70,000	0.05%	$3.3M	—
121	GROUP ONE TRADING LLC	63,943	0.05%	$3.0M	-23,889 (-27.2%)
122	ALGERT GLOBAL LLC	63,700	0.05%	$3.0M	NEW
123	MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd.	59,936	0.04%	$2.8M	+13,743 (+29.8%)
124	Vanguard Global Advisers, LLC	56,942	0.04%	$2.7M	+8,898 (+18.5%)
125	PEAK FINANCIAL ADVISORS LLC	56,915	0.04%	$2.7M	NEW
126	Y-Intercept (Hong Kong) Ltd	54,466	0.04%	$2.6M	NEW
127	Cerity Partners LLC	53,883	0.04%	$2.5M	NEW
128	BLAIR WILLIAM & CO/IL	53,588	0.04%	$2.5M	-107 (-0.2%)
129	STATE OF WISCONSIN INVESTMENT BOARD	52,549	0.04%	$2.5M	+2,129 (+4.2%)
130	Moody Aldrich Partners LLC	51,025	0.04%	$2.4M	NEW
131	KESTRA PRIVATE WEALTH SERVICES, LLC	50,588	0.04%	$2.4M	—
132	BARCLAYS PLC	50,296	0.04%	$2.4M	+10,613 (+26.7%)
133	Atom Investors LP	49,436	0.04%	$2.3M	NEW
134	NISA INVESTMENT ADVISORS, LLC	48,369	0.04%	$2.3M	-534 (-1.1%)
135	SIMPLEX TRADING, LLC	47,651	0.04%	$2.2M	+6,495 (+15.8%)
136	NEW YORK STATE COMMON RETIREMENT FUND	45,800	0.03%	$2.2M	+16,200 (+54.7%)
137	ALLSTATE CORP	45,639	0.03%	$2.1M	+273 (+0.6%)
138	JENNISON ASSOCIATES LLC	45,375	0.03%	$2.1M	+5,418 (+13.6%)
139	Caption Management, LLC	45,000	0.03%	$2.1M	+11,242 (+33.3%)
140	Polymer Capital Management (HK) LTD	44,100	0.03%	$2.1M	NEW
141	Aquatic Capital Management LLC	43,124	0.03%	$2.0M	NEW
142	Ghisallo Capital Management LLC	41,500	0.03%	$2.0M	NEW
143	CenterBook Partners LP	41,255	0.03%	$1.9M	-1,574 (-3.7%)
144	SUSQUEHANNA INTERNATIONAL GROUP, LLP	40,954	0.03%	$1.9M	-40,502 (-49.7%)
145	Police & Firemen's Retirement System of New Jersey	38,386	0.03%	$1.8M	+11,025 (+40.3%)
146	TD Waterhouse Canada Inc.	36,694	0.03%	$1.6M	+34,892 (+1936.3%)
147	SCOTIA CAPITAL INC.	34,722	0.03%	$1.6M	-5,826 (-14.4%)
148	STRS OHIO	33,500	0.02%	$1.6M	+14,200 (+73.6%)
149	Zurcher Kantonalbank (Zurich Cantonalbank)	32,394	0.02%	$1.5M	+11,526 (+55.2%)
150	KINGSWOOD WEALTH ADVISORS, LLC	31,444	0.02%	$1.5M	+4,853 (+18.3%)
151	Bay Rivers Group	31,208	0.02%	$1.5M	+4,862 (+18.5%)
152	Vestmark Advisory Solutions, Inc.	30,729	0.02%	$1.4M	NEW
153	State of New Jersey Common Pension Fund D	30,625	0.02%	$1.4M	+3,184 (+11.6%)
154	ARIZONA STATE RETIREMENT SYSTEM	30,411	0.02%	$1.4M	+8,357 (+37.9%)
155	Palumbo Wealth Management LLC	29,287	0.02%	$1.4M	-8,679 (-22.9%)
156	SEI INVESTMENTS CO	28,582	0.02%	$1.3M	+465 (+1.7%)
157	Cinctive Capital Management LP	28,550	0.02%	$1.3M	+15,999 (+127.5%)
158	Vanguard Investments Australia, Ltd.	28,265	0.02%	$1.3M	+7,798 (+38.1%)
159	SG Americas Securities, LLC	28,262	0.02%	$1.3M	+17,769 (+169.3%)
160	Mariner, LLC	27,207	0.02%	$1.3M	-7,644 (-21.9%)
161	STABLEFORD CAPITAL II LLC	27,141	0.02%	$1.3M	NEW
162	Janney Montgomery Scott LLC	26,664	0.02%	$1.3M	NEW
163	ACT CAPITAL MANAGEMENT, LLC	25,000	0.02%	$1.2M	NEW
164	KLP KAPITALFORVALTNING AS	25,000	0.02%	$1.2M	NEW
165	TEACHERS RETIREMENT SYSTEM OF THE STATE OF KENTUCKY	24,500	0.02%	$1.2M	NEW
166	Corient Private Wealth LP	24,391	0.02%	$1.1M	NEW
167	Rathbones Group PLC	22,800	0.02%	$1.1M	-37,600 (-62.3%)
168	RAYMOND JAMES FINANCIAL INC	22,401	0.02%	$1.1M	-1,312 (-5.5%)
169	HighTower Advisors, LLC	22,313	0.02%	$1.0M	+3,754 (+20.2%)
170	IFG Advisory, LLC	22,043	0.02%	$1.0M	NEW
171	TFB Advisors LLC	21,523	0.02%	$1.0M	NEW
172	China Universal Asset Management Co., Ltd.	21,358	0.02%	$1.0M	+1,166 (+5.8%)
173	Walleye Capital LLC	20,643	0.02%	$971K	-14,842 (-41.8%)
174	ProShare Advisors LLC	20,615	0.02%	$970K	+1,884 (+10.1%)
175	Concurrent Investment Advisors, LLC	20,044	0.01%	$943K	-1,241 (-5.8%)
176	Fore Capital, LLC	20,000	0.01%	$941K	NEW
177	Birchview Capital, LP	20,000	0.01%	$941K	NEW
178	INTECH INVESTMENT MANAGEMENT LLC	19,969	0.01%	$939K	-5,021 (-20.1%)
179	Walleye Trading LLC	18,450	0.01%	$868K	+13,036 (+240.8%)
180	Sequoia Financial Advisors, LLC	17,258	0.01%	$812K	+13 (+0.1%)
181	ENVESTNET ASSET MANAGEMENT INC	16,626	0.01%	$782K	NEW
182	CARY STREET PARTNERS FINANCIAL LLC	15,582	0.01%	$733K	NEW
183	PRUDENTIAL FINANCIAL INC	15,500	0.01%	$729K	NEW
184	DIADEMA PARTNERS LP	15,451	0.01%	$727K	NEW
185	Twelve Points Wealth Management LLC	14,245	0.01%	$670K	+2,000 (+16.3%)
186	Pictet Asset Management Holding SA	14,077	0.01%	$662K	+782 (+5.9%)
187	Amundi	14,068	0.01%	$662K	-68 (-0.5%)
188	Cetera Investment Advisers	14,029	0.01%	$660K	-17,795 (-55.9%)
189	Allianz Asset Management GmbH	13,800	0.01%	$649K	NEW
190	Persistent Asset Partners Ltd	13,778	0.01%	$648K	-2,083 (-13.1%)
191	PROFUND ADVISORS LLC	13,571	0.01%	$638K	-625 (-4.4%)
192	FORA Capital, LLC	13,378	0.01%	$629K	NEW
193	Private Advisor Group, LLC	13,336	0.01%	$627K	NEW
194	DYMON ASIA CAPITAL (SINGAPORE) PTE. LTD.	13,289	0.01%	$625K	NEW
195	Virtus Investment Advisers, LLC	13,220	0.01%	$622K	-8,507 (-39.2%)
196	MONEY CONCEPTS CAPITAL CORP	13,000	0.01%	$612K	—
197	XPONANCE LLC	12,716	0.01%	$598K	NEW
198	State of Wyoming	12,448	0.01%	$586K	NEW
199	AXQ CAPITAL, LP	12,444	0.01%	$585K	NEW
200	STIFEL FINANCIAL CORP	12,225	0.01%	$575K	-401 (-3.2%)
201	CAPTRUST FINANCIAL ADVISORS	12,148	0.01%	$571K	NEW
202	Heritage Wealth Management, Inc. /CA/	12,000	0.01%	$564K	-2,375 (-16.5%)
203	OSAIC HOLDINGS, INC.	11,952	0.01%	$562K	+1,393 (+13.2%)
204	Ameritas Investment Partners, Inc.	11,736	0.01%	$552K	+4,095 (+53.6%)
205	GLENMEDE TRUST CO NA	11,548	0.01%	$543K	NEW
206	Steward Partners Investment Advisory, LLC	11,540	0.01%	$543K	-1,700 (-12.8%)
207	Sanctuary Advisors, LLC	11,502	0.01%	$541K	+36 (+0.3%)
208	ELEVATION POINT WEALTH PARTNERS, LLC	11,382	0.01%	$535K	NEW
209	TEACHER RETIREMENT SYSTEM OF TEXAS	11,072	0.01%	$521K	+772 (+7.5%)
210	Entropy Technologies, LP	10,688	0.01%	$503K	NEW
211	Cambridge Investment Research Advisors, Inc.	10,534	0.01%	$496K	NEW
212	MERCER GLOBAL ADVISORS INC /ADV	10,278	0.01%	$483K	NEW
213	Engineers Gate Manager LP	10,233	0.01%	$481K	-19,534 (-65.6%)
214	CAPITAL FUND MANAGEMENT S.A.	10,128	0.01%	$476K	NEW
215	BANK OF MONTREAL /CAN/	10,030	0.01%	$472K	-2,106 (-17.4%)
216	DIVERSIFY WEALTH MANAGEMENT, LLC	10,025	0.01%	$428K	-975 (-8.9%)
217	Diversify Advisory Services, LLC	10,025	0.01%	$428K	NEW
218	King Wealth Management Group	10,000	0.01%	$470K	—
219	SHARPEPOINT LLC	10,000	0.01%	$470K	—
220	PSP Research LLC	10,000	0.01%	$470K	-24,800 (-71.3%)
221	PRINCIPAL FINANCIAL GROUP INC	9,952	0.01%	$468K	NEW
222	CIBC WORLD MARKET INC.	9,827	0.01%	$462K	-222 (-2.2%)
223	FIRST TRUST ADVISORS LP	9,527	0.01%	$448K	NEW
224	COMMONWEALTH EQUITY SERVICES, LLC	9,450	0.01%	$445K	-801 (-7.8%)
225	Quantbot Technologies LP	9,230	0.01%	$434K	NEW
226	Federation des caisses Desjardins du Quebec	9,104	0.01%	$428K	-3,540 (-28.0%)
227	MANGROVE PARTNERS IM, LLC	9,079	0.01%	$427K	NEW
228	GSA CAPITAL PARTNERS LLP	9,073	0.01%	$427K	-9,082 (-50.0%)
229	Fearless Solutions, LLC dba Best Invest	8,804	0.01%	$414K	NEW
230	North Star Investment Management Corp.	8,571	0.01%	$403K	+1,000 (+13.2%)
231	PNC Financial Services Group, Inc.	8,569	0.01%	$403K	+949 (+12.5%)
232	Rafferty Asset Management, LLC	8,548	0.01%	$402K	NEW
233	Fieldview Capital Management, LLC	8,493	0.01%	$400K	NEW
234	Bellevue Group AG	8,391	0.01%	$395K	NEW
235	Connor, Clark & Lunn Investment Management Ltd.	8,295	0.01%	$390K	NEW
236	FLAGSHIP HARBOR ADVISORS, LLC	7,966	0.01%	$375K	NEW
237	WEALTH ENHANCEMENT ADVISORY SERVICES, LLC	7,952	0.01%	$374K	NEW
238	CIBC Bancorp USA Inc.	7,711	0.01%	$363K	NEW
239	OMERS ADMINISTRATION Corp	7,600	0.01%	$358K	NEW
240	Abel Hall, LLC	7,551	0.01%	$355K	NEW
241	FIDUCIARY FINANCIAL ADVISORS	7,483	0.01%	$352K	NEW
242	EntryPoint Capital, LLC	7,331	0.01%	$345K	NEW
243	Chicago Partners Investment Group LLC	7,299	0.01%	$313K	-2,008 (-21.6%)
244	Centiva Capital, LP	7,242	0.01%	$341K	NEW
245	CreativeOne Wealth, LLC	7,202	0.01%	$339K	NEW
246	Jump Financial, LLC	7,064	0.01%	$332K	NEW
247	CHIRON CAPITAL MANAGEMENT, LLC	7,000	0.01%	$329K	NEW
248	Creative Planning	6,906	0.01%	$325K	NEW
249	McAdam, LLC	6,879	0.01%	$324K	NEW
250	Marex Group Ltd	6,771	0.01%	$319K	-13,229 (-66.1%)

Exited since 2026-03-31 (34 filers; largest 25 shown)

JANUS HENDERSON GROUP PLC	−3,556,041
Trails Edge Capital Partners, LP	−1,738,110
Patient Square Capital LP	−331,000
JANE STREET GROUP, LLC	−260,241
Soviero Asset Management, LP	−140,000
Squarepoint Ops LLC	−125,522
Rosalind Advisors, Inc.	−125,000
ExodusPoint Capital Management, LP	−104,915
HRT FINANCIAL LP	−89,141
Ikarian Capital, LLC	−58,803
TWINBEECH CAPITAL LP	−42,100
CAXTON ASSOCIATES LLP	−37,255
Campbell & CO Investment Adviser LLC	−24,755
FOX RUN MANAGEMENT, L.L.C.	−14,557
Virtu Financial LLC	−14,460
BOOTHBAY FUND MANAGEMENT, LLC	−14,096
Magnetar Financial LLC	−13,178
Summit Trail Advisors, LLC	−13,000
RPS ADVISORY SOLUTIONS LLC	−11,355
Dynamic Technology Lab Private Ltd	−10,880
Verition Fund Management LLC	−10,384
CWM, LLC	−5,600
Sound Income Strategies, LLC	−3,690
Advisory Services Network, LLC	−2,659
Opal Wealth Advisors, LLC	−1,101

Large holders from 13D/13G (latest per reporting person, last 2 years)

Filed when a holder crosses 5% or changes materially, so often more current than the quarter-end 13F. Percentages are the filer's own, against the share count they used.

Reporting person	Form	Filed	Event	Shares	% of class
Commodore Capital LP	SCHEDULE 13G/A	2026-08-14	2026-06-30	2,410,000	1.8%
Commodore Capital Master LP	SCHEDULE 13G/A	2026-08-14	2026-06-30	2,410,000	1.8%
DRIEHAUS CAPITAL MANAGEMENT LLC	SCHEDULE 13G/A	2026-08-14	2026-06-30	6,845,276	5.36%
Michael Kramarz	SCHEDULE 13G/A	2026-08-14	2026-06-30	2,410,000	1.8%
Robert Egen Atkinson	SCHEDULE 13G/A	2026-08-14	2026-06-30	2,410,000	1.8%
David Kroin	SCHEDULE 13G/A	2026-05-15	2026-03-31	3,000,000	3.01%
Deep Track Biotechnology Master Fund, Ltd.	SCHEDULE 13G/A	2026-05-15	2026-03-31	3,000,000	3.01%
Deep Track Capital, LP	SCHEDULE 13G/A	2026-05-15	2026-03-31	3,000,000	3.01%
Avoro Capital Advisors LLC	SCHEDULE 13G	2026-02-17	2025-12-31	5,000,000	5.08%
Behzad Aghazadeh	SCHEDULE 13G	2026-02-17	2025-12-31	5,000,000	5.08%
BlackRock, Inc.	SCHEDULE 13G/A	2025-02-05	2024-12-31	6,070,053	8.3%

Source: SEC Form 13F-HR information tables for the quarter ending 2026-06-30 (filed within 45 days of quarter end; amendments applied; values normalised to dollars), the share count from the company's latest 10-K/10-Q XBRL cover page, and Schedule 13D/13G filings. Each row is a legal 13F filer as filed — related entities (e.g. Vanguard's advisers) are not merged. Retail brokerage accounts are not reported on 13F, so the remainder is mostly retail and insiders.