Institutional HoldersBeta

Who holds a company, from every 13F filed for the quarter, one row per filer exactly as filed, against the latest share count the company reported.

EyePoint, Inc.

CIK 0001314102EYPT· quarter ending 2026-06-30

Shares outstanding

86,212,138

as of 2026-07-31 · 10-Q cover page, filed 2026-08-05

Held by 13F filers

92,818,594

107.7% of shares outstanding

Holders

188

-1 vs 2026-03-31 · 24 new, 25 exited

Value

$1.3B

shares +3.0% vs prior quarter

13F holdings exceed the share count. This is normal for heavily shorted stocks: shares lent to short sellers are reported by the lender and again by whoever bought them. Related filers occasionally report the same position twice as well.

Share classes (cover page of the 10-Q filed 2026-08-05, as of 2026-07-31)

Class	Listed	Shares outstanding	Held by 13F filers	% of class	Holders	CUSIP
Common stock	EYPT · NASDAQ	86,212,138	92,818,594	107.7%	188	30233G209

Each class is compared with its own share count; classes are not added together. A class that is not exchange-listed cannot be held by 13F filers.

Securities (CUSIPs held in 13F this quarter)

tick to combine

Count	CUSIP	Class (as filers write it)	Holders	Shares held	Class shares	% of class	Value	Options	Mapped via
	30233G209	COM NEW	188	92,818,594	86,212,138	107.7%	$1.3B	11 call / 8 put	13DG	holders →

Totals combine the ticked CUSIPs and update as you tick: common-stock classes by default; preferreds, notes, warrants and depositary shares are listed but not counted. "holders →" shows a single CUSIP on its own. Bonds are held as a principal amount, not shares. Options positions are never counted as holdings.

Top holders (188 of 188 · 30233G209)

change vs 2026-03-31

#	Filer	Shares	% of class	Value	Change
1	MONTANOVA CAPITAL, LLC	8,296,375	9.62%	$118.6M	—
2	BlackRock, Inc.	7,463,197	8.66%	$106.7M	+285,860 (+4.0%)
3	Cormorant Asset Management, LP	7,000,000	8.12%	$100.1M	-1,265,000 (-15.3%)
4	FEDERATED HERMES, INC.	5,681,052	6.59%	$81.2M	+11,463 (+0.2%)
5	ADAGE CAPITAL PARTNERS GP, L.L.C.	4,827,792	5.60%	$69.0M	+1,527,792 (+46.3%)
6	FRANKLIN RESOURCES INC	4,807,078	5.58%	$68.7M	-241,520 (-4.8%)
7	Commodore Capital LP	4,600,000	5.34%	$65.8M	+1,775,000 (+62.8%)
8	Jupiter Topco LLC	3,770,381	4.37%	$53.9M	NEW
9	VANGUARD CAPITAL MANAGEMENT LLC	3,630,252	4.21%	$51.9M	+70,683 (+2.0%)
10	Paradigm Biocapital Advisors LP	2,890,397	3.35%	$41.3M	-252,040 (-8.0%)
11	STATE STREET CORP	2,357,545	2.73%	$33.7M	+260,343 (+12.4%)
12	GEODE CAPITAL MANAGEMENT, LLC	2,062,390	2.39%	$29.5M	+78,725 (+4.0%)
13	Aberdeen Group plc	2,008,802	2.33%	$28.7M	+270,424 (+15.6%)
14	CITADEL ADVISORS LLC	1,977,610	2.29%	$28.3M	+71,735 (+3.8%)
15	Balyasny Asset Management L.P.	1,812,358	2.10%	$25.9M	+373,621 (+26.0%)
16	Parkman Healthcare Partners LLC	1,288,163	1.49%	$18.4M	-66,637 (-4.9%)
17	EVENTIDE ASSET MANAGEMENT, LLC	1,245,583	1.44%	$17.8M	—
18	TWO SIGMA INVESTMENTS, LP	1,181,143	1.37%	$16.9M	+750,828 (+174.5%)
19	Essex Woodlands Management, Inc.	1,084,857	1.26%	$15.5M	—
20	ORBIMED ADVISORS LLC	1,069,147	1.24%	$15.3M	—
21	5AM Venture Management, LLC	1,050,000	1.22%	$15.0M	—
22	Rosalind Advisors, Inc.	988,230	1.15%	$14.1M	-48,507 (-4.7%)
23	VANGUARD PORTFOLIO MANAGEMENT LLC	971,014	1.13%	$13.9M	+177,144 (+22.3%)
24	AMERIPRISE FINANCIAL INC	848,410	0.98%	$12.1M	+425,148 (+100.4%)
25	DIMENSIONAL FUND ADVISORS LP	841,746	0.98%	$12.0M	+440,625 (+109.8%)
26	HSBC HOLDINGS PLC	833,455	0.97%	$11.9M	—
27	Candriam S.C.A.	787,769	0.91%	$11.3M	+113,374 (+16.8%)
28	Artia Global Partners LP	767,098	0.89%	$11.0M	—
29	Blue Owl Capital Holdings LP	762,594	0.88%	$10.9M	-150,000 (-16.4%)
30	NORTHERN TRUST CORP	720,917	0.84%	$10.3M	+44,105 (+6.5%)
31	Patient Square Capital LP	720,000	0.84%	$10.3M	-75,000 (-9.4%)
32	Principia Wealth Advisory, LLC	649,944	0.75%	$9.3M	+16,180 (+2.6%)
33	CHARLES SCHWAB INVESTMENT MANAGEMENT INC	647,613	0.75%	$9.3M	+7,490 (+1.2%)
34	Sio Capital Management, LLC	623,130	0.72%	$8.9M	-98,655 (-13.7%)
35	VANGUARD FIDUCIARY TRUST CO	559,216	0.65%	$8.0M	+54,744 (+10.9%)
36	Alyeska Investment Group, L.P.	509,403	0.59%	$7.3M	—
37	MILLENNIUM MANAGEMENT LLC	500,093	0.58%	$7.2M	+24,903 (+5.2%)
38	GOLDMAN SACHS GROUP INC	465,087	0.54%	$6.7M	-234,619 (-33.5%)
39	Simplify Asset Management Inc.	400,044	0.46%	$5.7M	+73,902 (+22.7%)
40	Ghisallo Capital Management LLC	350,000	0.41%	$5.0M	NEW
41	STEMPOINT CAPITAL LP	338,471	0.39%	$4.8M	-1,283,057 (-79.1%)
42	MORGAN STANLEY	336,730	0.39%	$4.8M	-759,379 (-69.3%)
43	E Fund Management Co., Ltd.	330,774	0.38%	$4.7M	+236,274 (+250.0%)
44	Jump Financial, LLC	320,757	0.37%	$4.6M	+122,357 (+61.7%)
45	Bleichroeder LP	316,515	0.37%	$4.5M	—
46	Woodline Partners LP	300,463	0.35%	$4.3M	+200,000 (+199.1%)
47	Eversept Partners, LP	297,735	0.35%	$4.3M	NEW
48	Rock Springs Capital Management LP	268,519	0.31%	$3.8M	+9,780 (+3.8%)
49	CITIGROUP INC	266,910	0.31%	$3.8M	+238,028 (+824.1%)
50	Bank of New York Mellon Corp	250,783	0.29%	$3.6M	-4,598 (-1.8%)
51	MYDA Advisors LLC	250,000	0.29%	$3.6M	-80,000 (-24.2%)
52	UBS Group AG	241,363	0.28%	$3.5M	+111,908 (+86.4%)
53	BNP PARIBAS ASSET MANAGEMENT Holding S.A.	234,809	0.27%	$3.4M	-10,550 (-4.3%)
54	Schonfeld Strategic Advisors LLC	229,780	0.27%	$3.3M	+22,660 (+10.9%)
55	WELLINGTON MANAGEMENT GROUP LLP	228,559	0.27%	$3.3M	-30,383 (-11.7%)
56	Nuveen, LLC	193,480	0.22%	$2.8M	-66,796 (-25.7%)
57	Propel Bio Management, LLC	191,745	0.22%	$2.7M	-24,080 (-11.2%)
58	Qube Research & Technologies Ltd	189,102	0.22%	$2.7M	+72,625 (+62.4%)
59	Walleye Capital LLC	188,221	0.22%	$2.7M	-111,963 (-37.3%)
60	Susquehanna Portfolio Strategies, LLC	187,801	0.22%	$2.7M	+48,426 (+34.7%)
61	SCHRODER INVESTMENT MANAGEMENT GROUP	169,334	0.20%	$2.4M	-49,216 (-22.5%)
62	HighVista Strategies LLC	155,704	0.18%	$2.2M	-27,333 (-14.9%)
63	DEUTSCHE BANK AG\	152,799	0.18%	$2.2M	-86,263 (-36.1%)
64	Granahan Investment Management, LLC	149,387	0.17%	$2.1M	-147,721 (-49.7%)
65	Swiss National Bank	142,300	0.17%	$2.0M	-5,100 (-3.5%)
66	STATE OF WISCONSIN INVESTMENT BOARD	139,770	0.16%	$2.0M	+13,065 (+10.3%)
67	UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC	135,340	0.16%	$1.9M	-14,521 (-9.7%)
68	PANAGORA ASSET MANAGEMENT INC	132,214	0.15%	$1.9M	—
69	Corient Private Wealth LP	127,199	0.15%	$1.8M	-303 (-0.2%)
70	PRICE T ROWE ASSOCIATES INC /MD/	124,989	0.14%	$1.8M	+18,851 (+17.8%)
71	ESSEX INVESTMENT MANAGEMENT CO LLC	121,684	0.14%	$1.7M	-5,529 (-4.3%)
72	Invesco Ltd.	116,204	0.13%	$1.7M	-15,737 (-11.9%)
73	Russell Investments Group, Ltd.	110,069	0.13%	$1.6M	+38,438 (+53.7%)
74	CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM	102,640	0.12%	$1.5M	-2,461 (-2.3%)
75	Squarepoint Ops LLC	98,002	0.11%	$1.4M	+17,883 (+22.3%)
76	RHUMBLINE ADVISERS	97,437	0.11%	$1.4M	+760 (+0.8%)
77	SG Americas Securities, LLC	88,802	0.10%	$1.3M	NEW
78	ALGERT GLOBAL LLC	78,990	0.09%	$1.1M	NEW
79	Waverly Advisors, LLC	77,914	0.09%	$1.1M	—
80	ALLIANCEBERNSTEIN L.P.	75,336	0.09%	$971K	—
81	Cinctive Capital Management LP	72,582	0.08%	$1.0M	+44,721 (+160.5%)
82	WELLS FARGO & COMPANY/MN	70,739	0.08%	$1.0M	+41,447 (+141.5%)
83	WOODSTOCK CORP	68,465	0.08%	$979K	—
84	BANK OF AMERICA CORP /DE/	65,048	0.08%	$930K	-318,395 (-83.0%)
85	JANE STREET GROUP, LLC	62,939	0.07%	$900K	+26,010 (+70.4%)
86	Zurcher Kantonalbank (Zurich Cantonalbank)	60,539	0.07%	$866K	+38,891 (+179.7%)
87	Legal & General Group Plc	59,220	0.07%	$847K	+6,103 (+11.5%)
88	FOX RUN MANAGEMENT, L.L.C.	58,528	0.07%	$837K	NEW
89	HRT FINANCIAL LP	57,212	0.07%	$818K	NEW
90	Y-Intercept (Hong Kong) Ltd	51,190	0.06%	$732K	NEW
91	VOYA INVESTMENT MANAGEMENT LLC	50,089	0.06%	$716K	+2,318 (+4.9%)
92	JPMORGAN CHASE & CO	50,053	0.06%	$706K	+9,941 (+24.8%)
93	SILVERBACK ASSET MANAGEMENT LLC	50,000	0.06%	$715K	—
94	Erste Asset Management GmbH	50,000	0.06%	$706K	—
95	VANGUARD ASSET MANAGEMENT, Ltd	49,129	0.06%	$703K	—
96	Point72 Asset Management, L.P.	48,574	0.06%	$695K	NEW
97	SBI Okasan Asset Management Co.Ltd.	45,700	0.05%	$645K	—
98	BARCLAYS PLC	43,948	0.05%	$628K	+17,789 (+68.0%)
99	MetLife Investment Management, LLC	43,469	0.05%	$622K	—
100	SCOTIA CAPITAL INC.	41,751	0.05%	$597K	—
101	Marex Group Ltd	41,300	0.05%	$591K	-15,013 (-26.7%)
102	Legato Capital Management LLC	41,047	0.05%	$587K	+1,172 (+2.9%)
103	Magnetar Financial LLC	39,737	0.05%	$568K	NEW
104	Vanguard Global Advisers, LLC	38,888	0.05%	$556K	—
105	China Universal Asset Management Co., Ltd.	38,343	0.04%	$548K	-1,348 (-3.4%)
106	MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd.	35,635	0.04%	$510K	-691 (-1.9%)
107	MANUFACTURERS LIFE INSURANCE COMPANY, THE	35,134	0.04%	$502K	-938 (-2.6%)
108	HighTower Advisors, LLC	33,538	0.04%	$480K	+1,039 (+3.2%)
109	Baird Financial Group, Inc.	32,732	0.04%	$468K	+4,613 (+16.4%)
110	NISA INVESTMENT ADVISORS, LLC	29,279	0.03%	$419K	-15,193 (-34.2%)
111	Janney Montgomery Scott LLC	28,385	0.03%	$406K	-1,930 (-6.4%)
112	Creative Planning	27,743	0.03%	$397K	-5,337 (-16.1%)
113	SEI INVESTMENTS CO	27,711	0.03%	$396K	-22,795 (-45.1%)
114	Jain Global LLC	27,660	0.03%	$396K	NEW
115	NEW YORK STATE COMMON RETIREMENT FUND	27,114	0.03%	$388K	+8,400 (+44.9%)
116	Virtu Financial LLC	26,380	0.03%	$377K	NEW
117	FMR LLC	26,155	0.03%	$374K	-103,283 (-79.8%)
118	SUSQUEHANNA INTERNATIONAL GROUP, LLP	25,421	0.03%	$364K	-12,260 (-32.5%)
119	Virtus Investment Advisers, LLC	25,111	0.03%	$359K	+8,059 (+47.3%)
120	Cyndeo Wealth Partners, LLC	24,190	0.03%	$346K	+750 (+3.2%)
121	MARSHALL WACE, LLP	23,934	0.03%	$342K	-137,850 (-85.2%)
122	Police & Firemen's Retirement System of New Jersey	23,184	0.03%	$332K	+3,111 (+15.5%)
123	State of New Jersey Common Pension Fund D	22,930	0.03%	$328K	-2,534 (-10.0%)
124	PROFUND ADVISORS LLC	22,136	0.03%	$317K	+5,222 (+30.9%)
125	GUGGENHEIM CAPITAL LLC	20,900	0.02%	$299K	+4,794 (+29.8%)
126	Vanguard Investments Australia, Ltd.	20,431	0.02%	$292K	—
127	INTECH INVESTMENT MANAGEMENT LLC	19,753	0.02%	$282K	+1,093 (+5.9%)
128	ARIZONA STATE RETIREMENT SYSTEM	19,568	0.02%	$280K	-897 (-4.4%)
129	LEVIN CAPITAL STRATEGIES, L.P.	19,000	0.02%	$272K	-12,500 (-39.7%)
130	RAYMOND JAMES FINANCIAL INC	17,165	0.02%	$245K	+1,265 (+8.0%)
131	TUDOR INVESTMENT CORP ET AL	16,749	0.02%	$240K	NEW
132	KLP KAPITALFORVALTNING AS	16,400	0.02%	$235K	—
133	Rafferty Asset Management, LLC	16,111	0.02%	$230K	NEW
134	ROYAL BANK OF CANADA	15,879	0.02%	$228K	+4,461 (+39.1%)
135	OXFORD ASSET MANAGEMENT LLP	14,381	0.02%	$206K	NEW
136	Quantinno Capital Management LP	14,088	0.02%	$201K	NEW
137	Brevan Howard Capital Management LP	13,526	0.02%	$193K	NEW
138	BNP PARIBAS FINANCIAL MARKETS	12,907	0.01%	$185K	-29,616 (-69.6%)
139	ProShare Advisors LLC	12,882	0.01%	$184K	-2,058 (-13.8%)
140	PRUDENTIAL FINANCIAL INC	12,670	0.01%	$181K	+750 (+6.3%)
141	Tower Research Capital LLC (TRC)	11,546	0.01%	$165K	+7,545 (+188.6%)
142	STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM	11,450	0.01%	$164K	—
143	Engineers Gate Manager LP	11,247	0.01%	$161K	NEW
144	Pictet Asset Management Holding SA	10,962	0.01%	$157K	—
145	GREAT VALLEY ADVISOR GROUP, INC.	10,750	0.01%	$154K	—
146	PSP Research LLC	10,000	0.01%	$143K	—
147	NATIXIS	8,403	0.01%	$120K	NEW
148	Ameritas Investment Partners, Inc.	7,023	0.01%	$100K	+889 (+14.5%)
149	MCF Advisors LLC	6,420	0.01%	$92K	-7,000 (-52.2%)
150	OSAIC HOLDINGS, INC.	5,300	0.01%	$76K	-241 (-4.3%)
151	Mirae Asset Global Investments Co., Ltd.	3,750	0.00%	$54K	-568 (-13.2%)
152	US BANCORP \DE\	3,620	0.00%	$52K	+3,578 (+8519.0%)
153	State of Alaska, Department of Revenue	3,579	0.00%	$51K	—
154	JONES FINANCIAL COMPANIES LLLP	2,805	0.00%	$38K	+693 (+32.8%)
155	KBC Group NV	2,266	0.00%	$32K	—
156	GF FUND MANAGEMENT CO. LTD.	1,754	0.00%	$25K	-105 (-5.6%)
157	Rockefeller Capital Management L.P.	1,550	0.00%	$22K	-613 (-28.3%)
158	NORTHWESTERN MUTUAL WEALTH MANAGEMENT CO	1,510	0.00%	$22K	+470 (+45.2%)
159	Versant Capital Management, Inc	1,270	0.00%	$18K	—
160	GAMMA Investing LLC	1,179	0.00%	$17K	-204 (-14.8%)
161	Cedar Mountain Advisors, LLC	1,000	0.00%	$14K	—
162	SIGNATUREFD, LLC	866	0.00%	$12K	-272 (-23.9%)
163	TOTH FINANCIAL ADVISORY CORP	800	0.00%	$11K	-1,201 (-60.0%)
164	Allworth Financial LP	609	0.00%	$9K	-66 (-9.8%)
165	PNC Financial Services Group, Inc.	593	0.00%	$8K	+49 (+9.0%)
166	MassMutual Private Wealth & Trust, FSB	569	0.00%	$8K	+54 (+10.5%)
167	Farther Finance Advisors, LLC	533	0.00%	$8K	-41 (-7.1%)
168	Parallel Advisors, LLC	498	0.00%	$7K	—
169	Larson Financial Group LLC	489	0.00%	$7K	-18 (-3.6%)
170	Sterling Capital Management LLC	484	0.00%	$7K	-2,084 (-81.2%)
171	FIFTH THIRD BANCORP	445	0.00%	$6K	—
172	TD Waterhouse Canada Inc.	346	0.00%	$5K	NEW
173	Truvestments Capital LLC	258	0.00%	$4K	—
174	LOS ANGELES CAPITAL MANAGEMENT LLC	148	0.00%	$2K	—
175	EverSource Wealth Advisors, LLC	131	0.00%	$2K	-18 (-12.1%)
176	ROTHSCHILD INVESTMENT LLC	120	0.00%	$2K	—
177	Aster Capital Management (DIFC) Ltd	110	0.00%	$2K	NEW
178	Cornerstone Financial Management LLC	88	0.00%	$1K	—
179	Fortitude Family Office, LLC	78	0.00%	$1K	—
180	SBI Securities Co., Ltd.	57	0.00%	$815	+50 (+714.3%)
181	Arax Advisory Partners	52	0.00%	$744	NEW
182	Caitong International Asset Management Co., Ltd	49	0.00%	$701	-6,996 (-99.3%)
183	Covestor Ltd	34	0.00%	$0	+24 (+240.0%)
184	Silver Grove Financial Group, Inc.	27	0.00%	$386	NEW
185	Basecamp Wealth Advisors LLC	16	0.00%	$229	-54 (-77.1%)
186	Essential Partners LLC	11	0.00%	$157	—
187	NATIONAL BANK OF CANADA /FI/	10	0.00%	$143	NEW
188	Keating Financial Advisory Services, Inc.	1	0.00%	$14	—

Exited since 2026-03-31 (25 filers; largest 25 shown)

JANUS HENDERSON GROUP PLC	−3,601,168
ExodusPoint Capital Management, LP	−458,102
DIADEMA PARTNERS LP	−178,545
RENAISSANCE TECHNOLOGIES LLC	−117,300
XTX Topco Ltd	−66,646
Persistent Asset Partners Ltd	−58,995
TWINBEECH CAPITAL LP	−56,300
AQR CAPITAL MANAGEMENT LLC	−17,712
RWC Asset Management LLP	−17,652
LANDSCAPE CAPITAL MANAGEMENT, L.L.C.	−12,283
Dynamic Technology Lab Private Ltd	−12,067
Vanguard Personalized Indexing Management, LLC	−11,122
Scientech Research LLC	−10,405
AMERICAN CENTURY COMPANIES INC	−10,185
Winthrop Advisory Group LLC	−10,100
Aquatic Capital Management LLC	−6,387
CWM, LLC	−374
Centiva Capital, LP	−216
HUNTINGTON NATIONAL BANK	−144
QUADRANT CAPITAL GROUP LLC	−100
Advisory Services Network, LLC	−76
MAI Capital Management	−15
Root Financial Partners, LLC	−5
TWIN PEAKS WEALTH ADVISORS, LLC	−1
Hughes Financial Services, LLC	−1

Large holders from 13D/13G (latest per reporting person, last 2 years)

Filed when a holder crosses 5% or changes materially, so often more current than the quarter-end 13F. Percentages are the filer's own, against the share count they used.

Reporting person	Form	Filed	Event	Shares	% of class
Thomas R. Donahue	SCHEDULE 13G/A	2026-10-07	2026-09-30	6,934,414	8.04%
Ann C. Donahue	SCHEDULE 13G/A	2026-10-07	2026-09-30	6,934,414	8.04%
J. Christopher Donahue	SCHEDULE 13G/A	2026-10-07	2026-09-30	6,934,414	8.04%
Federated Hermes, Inc.	SCHEDULE 13G/A	2026-10-07	2026-09-30	6,934,414	8.04%
Voting Shares Irrevocable Trust	SCHEDULE 13G/A	2026-10-07	2026-09-30	6,934,414	8.04%
JANUS HENDERSON GROUP Ltd.	SCHEDULE 13G	2026-09-08	2026-08-31	9,366,332	10.9%
Cormorant Asset Management, LP	SCHEDULE 13G/A	2026-08-14	2026-06-30	7,000,000	8.35%
Bihua Chen	SCHEDULE 13G/A	2026-08-14	2026-06-30	7,000,000	8.35%
Robert Atchinson	SCHEDULE 13G	2026-08-12	2026-06-30	4,790,792	5.71%
Adage Capital Management, L.P.	SCHEDULE 13G	2026-08-12	2026-06-30	4,790,792	5.71%
Phillip Gross	SCHEDULE 13G	2026-08-12	2026-06-30	4,790,792	5.71%
Vanguard Capital Management	SCHEDULE 13G	2026-07-31	2026-06-30	4,223,415	5.03%
BlackRock, Inc.	SCHEDULE 13G/A	2026-07-28	2026-06-30	6,430,477	7.7%
Commodore Capital Master LP	SCHEDULE 13G	2026-06-03	2026-05-27	4,250,000	5.1%
Commodore Capital LP	SCHEDULE 13G	2026-06-03	2026-05-27	4,250,000	5.1%
Michael Kramarz	SCHEDULE 13G	2026-06-03	2026-05-27	4,250,000	5.1%
Robert Egen Atkinson	SCHEDULE 13G	2026-06-03	2026-05-27	4,250,000	5.1%
Paradigm BioCapital Advisors GP LLC	SCHEDULE 13G/A	2026-05-15	2026-03-31	3,142,437	3.8%
Paradigm BioCapital Advisors LP	SCHEDULE 13G/A	2026-05-15	2026-03-31	3,142,437	3.8%
Paradigm BioCapital International Fund Ltd.	SCHEDULE 13G/A	2026-05-15	2026-03-31	2,769,062	3.3%
Senai Asefaw, M.D.	SCHEDULE 13G/A	2026-05-15	2026-03-31	3,142,437	3.8%
The Vanguard Group	SCHEDULE 13G/A	2026-03-26	2026-03-13	0	0%
TCG Crossover GP II, LLC	SCHEDULE 13G/A	2026-02-17	2025-12-31	3,572,335	4.3%
TCG Crossover Fund II, L.P.	SCHEDULE 13G/A	2026-02-17	2025-12-31	3,572,335	4.3%
Chen Yu	SCHEDULE 13G/A	2026-02-17	2025-12-31	3,572,335	4.3%
Chen Bihua	SCHEDULE 13G/A	2025-12-08	2025-12-04	8,265,000	9.98%
Rajeev Shah	SCHEDULE 13G/A	2025-02-14	2024-12-31	3,181,818	4.7%
RA Capital Management, L.P.	SCHEDULE 13G/A	2025-02-14	2024-12-31	3,181,818	4.7%
RA Capital Healthcare Fund, L.P.	SCHEDULE 13G/A	2025-02-14	2024-12-31	3,181,818	4.7%
Peter Kolchinsky	SCHEDULE 13G/A	2025-02-14	2024-12-31	3,181,818	4.7%
Rupert H. Johnson, Jr.	SCHEDULE 13G/A	2025-01-27	2024-12-31	0	0%
Franklin Advisers, Inc.	SCHEDULE 13G/A	2025-01-27	2024-12-31	4,109,233	6%
Franklin Resources, Inc.	SCHEDULE 13G/A	2025-01-27	2024-12-31	4,137,567	6.1%
Charles B. Johnson	SCHEDULE 13G/A	2025-01-27	2024-12-31	0	0%

Source: SEC Form 13F-HR information tables for the quarter ending 2026-06-30 (filed within 45 days of quarter end; amendments applied; values normalised to dollars), the share count from the company's latest 10-K/10-Q XBRL cover page, and Schedule 13D/13G filings. Each row is a legal 13F filer as filed — related entities (e.g. Vanguard's advisers) are not merged. Retail brokerage accounts are not reported on 13F, so the remainder is mostly retail and insiders.