Income Taxes - Summary of Reconciliation of Statutory Federal Income Tax Rate (Details) |
12 Months Ended | ||
|---|---|---|---|
Dec. 31, 2021 |
Dec. 31, 2020 |
Dec. 31, 2019 |
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| Effective Income Tax Rate Continuing Operations Tax Rate Reconciliation [Abstract] | |||
| Tax benefit (expense) computed at the federal statutory rate | 21.00% | 21.00% | 21.00% |
| State tax benefit (expense), net of federal benefit | 31.50% | 8.30% | 7.60% |
| Change in valuation allowance | (246.30%) | (58.90%) | (38.50%) |
| Differences between U.S. and foreign tax rates on foreign income | 3.90% | (1.40%) | (1.00%) |
| Stock-based compensation benefit | 119.30% | 17.80% | 0.80% |
| U.S. federal research & development credit benefit | 36.70% | 8.40% | 6.30% |
| U.K. corporate rate increase | 39.80% | 4.30% | |
| Acquisitions and divestitures | (8.00%) | (0.50%) | 3.50% |
| Other benefits (expenses) | (0.80%) | (1.00%) | 0.30% |
| Total income tax benefit (expense) | (2.90%) | (2.00%) | 0.00% |
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- Definition Effective income tax rate reconciliation acquisitions and divestitures. No definition available.
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- Definition Effective income tax rate reconciliation change in foreign income tax rate. No definition available.
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- Definition Effective income tax rate reconciliation federal research & development credit benefit. No definition available.
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- Definition Effective income tax rate reconciliation nondeductible expense share based compensation cost benefit. No definition available.
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- Definition Percentage of current income tax expense (benefit) and deferred income tax expense (benefit) pertaining to continuing operations. Reference 1: http://www.xbrl.org/2003/role/disclosureRef
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- References No definition available.
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- Definition Percentage of domestic federal statutory tax rate applicable to pretax income (loss). Reference 1: http://www.xbrl.org/2003/role/disclosureRef
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- Definition Percentage of the difference between reported income tax expense (benefit) and expected income tax expense (benefit) computed by applying the domestic federal statutory income tax rates to pretax income (loss) from continuing operations attributable to changes in the valuation allowance for deferred tax assets. Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef
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- Definition Percentage of the difference between reported income tax expense (benefit) and expected income tax expense (benefit) computed by applying the domestic federal statutory income tax rates to pretax income (loss) from continuing operations applicable to statutory income tax expense (benefit) outside of the country of domicile. Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef
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- Definition Percentage of the difference between reported income tax expense (benefit) and expected income tax expense (benefit) computed by applying the domestic federal statutory income tax rates to pretax income (loss) from continuing operations attributable to other adjustments. Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef
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- Definition Percentage of the difference between reported income tax expense (benefit) and expected income tax expense (benefit) computed by applying the domestic federal statutory income tax rates to pretax income (loss) from continuing operations applicable to state and local income tax expense (benefit), net of federal tax expense (benefit). Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef
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