v3.25.4
Goodwill and Intangible Assets - Summary of Intangible Assets (Details) - USD ($)
$ in Millions
 3 Months Ended 12 Months Ended
Mar. 31, 2023
Dec. 31, 2025
Dec. 31, 2024
Dec. 31, 2023
Nov. 11, 2024
Definite-lived intangible assets          
Gross carrying amount   $ 89,592 $ 89,743    
Accumulated amortization   (42,232) (34,877)    
Net carrying amount   47,360 54,866    
Total intangible assets gross carrying amount   94,873 94,945    
Total intangible assets, net   52,641 60,068    
Indefinite-Lived Intangible Assets [Line Items]          
Indefinite-lived intangible assets   5,281 5,202    
Indefinite-Lived Intangible Assets (Excluding Goodwill), Fair Value Disclosure         $ 2,400
Impairment of intangible assets   847 $ 4,476 $ 4,229  
AGN-151607          
Indefinite-Lived Intangible Assets [Line Items]          
Impairment of intangible assets $ 630        
Impairment, Intangible Asset, Statement of Income or Comprehensive Income [Extensible Enumeration] Research and development        
Emraclidine          
Indefinite-Lived Intangible Assets [Line Items]          
Indefinite-lived intangible assets         $ 6,900
Impairment, Intangible Asset, Statement of Income or Comprehensive Income [Extensible Enumeration]     Research and development    
Impairment of Intangible Assets, Indefinite-Lived (Excluding Goodwill)     $ 4,500    
Developed product rights          
Definite-lived intangible assets          
Gross carrying amount   81,239 81,428    
Accumulated amortization   (34,849) (28,253)    
Net carrying amount   46,390 53,175    
License agreements          
Definite-lived intangible assets          
Gross carrying amount   8,353 8,315    
Accumulated amortization   (7,383) (6,624)    
Net carrying amount   $ 970 $ 1,691