Segment Information - Disaggregation of Revenue (Details) - USD ($) $ in Millions	3 Months Ended
Mar. 31, 2025	Mar. 31, 2024
Disaggregation of Revenue
Total net revenues	$ 13,343	$ 12,310
Collaborative Arrangement, Revenue Not from Contract with Customer, Statement of Income or Comprehensive Income [Extensible Enumeration]	Total net revenues	Total net revenues
All other
Disaggregation of Revenue
Net revenues	$ 747	$ 744
Immunology \| Skyrizi
Disaggregation of Revenue
Net revenues	3,425	2,008
Immunology \| Skyrizi \| United States
Disaggregation of Revenue
Net revenues	2,919	1,656
Immunology \| Skyrizi \| International
Disaggregation of Revenue
Net revenues	506	352
Immunology \| Rinvoq
Disaggregation of Revenue
Net revenues	1,718	1,093
Immunology \| Rinvoq \| United States
Disaggregation of Revenue
Net revenues	1,220	725
Immunology \| Rinvoq \| International
Disaggregation of Revenue
Net revenues	498	368
Immunology \| Humira
Disaggregation of Revenue
Net revenues	1,121	2,270
Immunology \| Humira \| United States
Disaggregation of Revenue
Net revenues	744	1,771
Immunology \| Humira \| International
Disaggregation of Revenue
Net revenues	377	499
Neuroscience \| Vraylar
Disaggregation of Revenue
Net revenues	765	694
Neuroscience \| Vraylar \| United States
Disaggregation of Revenue
Net revenues	763	692
Neuroscience \| Vraylar \| International
Disaggregation of Revenue
Net revenues	2	2
Neuroscience \| Botox Therapeutic
Disaggregation of Revenue
Net revenues	866	748
Neuroscience \| Botox Therapeutic \| United States
Disaggregation of Revenue
Net revenues	723	611
Neuroscience \| Botox Therapeutic \| International
Disaggregation of Revenue
Net revenues	143	137
Neuroscience \| Ubrelvy
Disaggregation of Revenue
Net revenues	240	203
Neuroscience \| Ubrelvy \| United States
Disaggregation of Revenue
Net revenues	233	197
Neuroscience \| Ubrelvy \| International
Disaggregation of Revenue
Net revenues	7	6
Neuroscience \| Qulipta
Disaggregation of Revenue
Net revenues	193	131
Neuroscience \| Qulipta \| United States
Disaggregation of Revenue
Net revenues	172	128
Neuroscience \| Qulipta \| International
Disaggregation of Revenue
Net revenues	21	3
Neuroscience \| Vyalev
Disaggregation of Revenue
Net revenues	63	9
Neuroscience \| Vyalev \| United States
Disaggregation of Revenue
Net revenues	6	0
Neuroscience \| Vyalev \| International
Disaggregation of Revenue
Net revenues	57	9
Neuroscience \| Duodopa
Disaggregation of Revenue
Net revenues	96	115
Neuroscience \| Duodopa \| United States
Disaggregation of Revenue
Net revenues	20	25
Neuroscience \| Duodopa \| International
Disaggregation of Revenue
Net revenues	76	90
Neuroscience \| Other Neuroscience
Disaggregation of Revenue
Net revenues	59	65
Neuroscience \| Other Neuroscience \| United States
Disaggregation of Revenue
Net revenues	55	61
Neuroscience \| Other Neuroscience \| International
Disaggregation of Revenue
Net revenues	4	4
Oncology \| Imbruvica
Disaggregation of Revenue
Net revenues	738	838
Oncology \| Imbruvica \| United States
Disaggregation of Revenue
Net revenues	529	610
Oncology \| Imbruvica \| International
Disaggregation of Revenue
Collaboration revenues	209	228
Oncology \| Venclexta
Disaggregation of Revenue
Net revenues	665	614
Oncology \| Venclexta \| United States
Disaggregation of Revenue
Net revenues	312	281
Oncology \| Venclexta \| International
Disaggregation of Revenue
Net revenues	353	333
Oncology \| Elahere
Disaggregation of Revenue
Net revenues	179	64
Oncology \| Elahere \| United States
Disaggregation of Revenue
Net revenues	165	64
Oncology \| Elahere \| International
Disaggregation of Revenue
Net revenues	14	0
Oncology \| Epkinly
Disaggregation of Revenue
Net revenues	51	27
Collaboration revenues	36	22
Oncology \| Epkinly \| International
Disaggregation of Revenue
Net revenues	15	5
Aesthetics \| Botox Cosmetic
Disaggregation of Revenue
Net revenues	556	633
Aesthetics \| Botox Cosmetic \| United States
Disaggregation of Revenue
Net revenues	295	389
Aesthetics \| Botox Cosmetic \| International
Disaggregation of Revenue
Net revenues	261	244
Aesthetics \| Juvederm Collection
Disaggregation of Revenue
Net revenues	231	297
Aesthetics \| Juvederm Collection \| United States
Disaggregation of Revenue
Net revenues	75	106
Aesthetics \| Juvederm Collection \| International
Disaggregation of Revenue
Net revenues	156	191
Aesthetics \| Other Aesthetics
Disaggregation of Revenue
Net revenues	315	319
Aesthetics \| Other Aesthetics \| United States
Disaggregation of Revenue
Net revenues	270	281
Aesthetics \| Other Aesthetics \| International
Disaggregation of Revenue
Net revenues	45	38
Eye Care \| Ozurdex
Disaggregation of Revenue
Net revenues	123	131
Eye Care \| Ozurdex \| United States
Disaggregation of Revenue
Net revenues	30	34
Eye Care \| Ozurdex \| International
Disaggregation of Revenue
Net revenues	93	97
Eye Care \| Lumigan/Ganfort
Disaggregation of Revenue
Net revenues	106	91
Eye Care \| Lumigan/Ganfort \| United States
Disaggregation of Revenue
Net revenues	48	29
Eye Care \| Lumigan/Ganfort \| International
Disaggregation of Revenue
Net revenues	58	62
Eye Care \| Alphagan/Combigan
Disaggregation of Revenue
Net revenues	60	59
Eye Care \| Alphagan/Combigan \| United States
Disaggregation of Revenue
Net revenues	26	15
Eye Care \| Alphagan/Combigan \| International
Disaggregation of Revenue
Net revenues	34	44
Eye Care \| Other Eye Care
Disaggregation of Revenue
Net revenues	217	257
Eye Care \| Other Eye Care \| United States
Disaggregation of Revenue
Net revenues	117	149
Eye Care \| Other Eye Care \| International
Disaggregation of Revenue
Net revenues	100	108
Other Key Products \| Mavyret
Disaggregation of Revenue
Net revenues	306	349
Other Key Products \| Mavyret \| United States
Disaggregation of Revenue
Net revenues	142	144
Other Key Products \| Mavyret \| International
Disaggregation of Revenue
Net revenues	164	205
Other Key Products \| Creon \| United States
Disaggregation of Revenue
Net revenues	355	285
Other Key Products \| Linzess/Constella
Disaggregation of Revenue
Net revenues	148	266
Other Key Products \| Linzess/Constella \| United States
Disaggregation of Revenue
Net revenues	139	257
Other Key Products \| Linzess/Constella \| International
Disaggregation of Revenue
Net revenues	$ 9	$ 9

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