Segment Information - Disaggregation of Revenue (Details) - USD ($) $ in Millions	3 Months Ended
Mar. 31, 2023	Mar. 31, 2022
Disaggregation of Revenue
Total net revenues	$ 12,225	$ 13,538
All other
Disaggregation of Revenue
Net revenues	691	1,211
Immunology \| Humira
Disaggregation of Revenue
Net revenues	3,541	4,736
Immunology \| Humira \| United States
Disaggregation of Revenue
Net revenues	2,948	3,993
Immunology \| Humira \| International
Disaggregation of Revenue
Net revenues	593	743
Immunology \| Skyrizi
Disaggregation of Revenue
Net revenues	1,360	940
Immunology \| Skyrizi \| United States
Disaggregation of Revenue
Net revenues	1,139	781
Immunology \| Skyrizi \| International
Disaggregation of Revenue
Net revenues	221	159
Immunology \| Rinvoq
Disaggregation of Revenue
Net revenues	686	465
Immunology \| Rinvoq \| United States
Disaggregation of Revenue
Net revenues	449	311
Immunology \| Rinvoq \| International
Disaggregation of Revenue
Net revenues	237	154
Hematologic Oncology \| Imbruvica
Disaggregation of Revenue
Net revenues	878	1,173
Hematologic Oncology \| Imbruvica \| United States
Disaggregation of Revenue
Net revenues	638	874
Hematologic Oncology \| Imbruvica \| International
Disaggregation of Revenue
Collaboration revenues	240	299
Hematologic Oncology \| Venclexta
Disaggregation of Revenue
Net revenues	538	473
Hematologic Oncology \| Venclexta \| United States
Disaggregation of Revenue
Net revenues	265	228
Hematologic Oncology \| Venclexta \| International
Disaggregation of Revenue
Net revenues	273	245
Aesthetics \| Botox Cosmetic
Disaggregation of Revenue
Net revenues	659	641
Aesthetics \| Botox Cosmetic \| United States
Disaggregation of Revenue
Net revenues	409	413
Aesthetics \| Botox Cosmetic \| International
Disaggregation of Revenue
Net revenues	250	228
Aesthetics \| Juvederm Collection
Disaggregation of Revenue
Net revenues	355	410
Aesthetics \| Juvederm Collection \| United States
Disaggregation of Revenue
Net revenues	122	148
Aesthetics \| Juvederm Collection \| International
Disaggregation of Revenue
Net revenues	233	262
Aesthetics \| Other Aesthetics
Disaggregation of Revenue
Net revenues	286	323
Aesthetics \| Other Aesthetics \| United States
Disaggregation of Revenue
Net revenues	246	285
Aesthetics \| Other Aesthetics \| International
Disaggregation of Revenue
Net revenues	40	38
Neuroscience \| Botox Therapeutic
Disaggregation of Revenue
Net revenues	719	614
Neuroscience \| Botox Therapeutic \| United States
Disaggregation of Revenue
Net revenues	587	500
Neuroscience \| Botox Therapeutic \| International
Disaggregation of Revenue
Net revenues	132	114
Neuroscience \| Vraylar
Disaggregation of Revenue
Net revenues	561	427
Neuroscience \| Vraylar \| United States
Disaggregation of Revenue
Net revenues	560	427
Neuroscience \| Vraylar \| International
Disaggregation of Revenue
Net revenues	1	0
Neuroscience \| Duodopa
Disaggregation of Revenue
Net revenues	118	121
Neuroscience \| Duodopa \| United States
Disaggregation of Revenue
Net revenues	25	24
Neuroscience \| Duodopa \| International
Disaggregation of Revenue
Net revenues	93	97
Neuroscience \| Ubrelvy
Disaggregation of Revenue
Net revenues	152	138
Neuroscience \| Ubrelvy \| United States
Disaggregation of Revenue
Net revenues	150	138
Neuroscience \| Ubrelvy \| International
Disaggregation of Revenue
Net revenues	2	0
Neuroscience \| Qulipta \| United States
Disaggregation of Revenue
Net revenues	66	11
Neuroscience \| Other Neuroscience
Disaggregation of Revenue
Net revenues	79	177
Neuroscience \| Other Neuroscience \| United States
Disaggregation of Revenue
Net revenues	75	173
Neuroscience \| Other Neuroscience \| International
Disaggregation of Revenue
Net revenues	4	4
Eye Care \| Ozurdex
Disaggregation of Revenue
Net revenues	115	107
Eye Care \| Ozurdex \| United States
Disaggregation of Revenue
Net revenues	39	33
Eye Care \| Ozurdex \| International
Disaggregation of Revenue
Net revenues	76	74
Eye Care \| Lumigan/Ganfort
Disaggregation of Revenue
Net revenues	130	140
Eye Care \| Lumigan/Ganfort \| United States
Disaggregation of Revenue
Net revenues	63	67
Eye Care \| Lumigan/Ganfort \| International
Disaggregation of Revenue
Net revenues	67	73
Eye Care \| Alphagan/Combigan
Disaggregation of Revenue
Net revenues	71	107
Eye Care \| Alphagan/Combigan \| United States
Disaggregation of Revenue
Net revenues	28	70
Eye Care \| Alphagan/Combigan \| International
Disaggregation of Revenue
Net revenues	43	37
Eye Care \| Restasis
Disaggregation of Revenue
Net revenues	92	246
Eye Care \| Restasis \| United States
Disaggregation of Revenue
Net revenues	79	235
Eye Care \| Restasis \| International
Disaggregation of Revenue
Net revenues	13	11
Eye Care \| Other Eye Care
Disaggregation of Revenue
Net revenues	200	171
Eye Care \| Other Eye Care \| United States
Disaggregation of Revenue
Net revenues	110	91
Eye Care \| Other Eye Care \| International
Disaggregation of Revenue
Net revenues	90	80
Other Key Products \| Mavyret
Disaggregation of Revenue
Net revenues	364	380
Other Key Products \| Mavyret \| United States
Disaggregation of Revenue
Net revenues	171	169
Other Key Products \| Mavyret \| International
Disaggregation of Revenue
Net revenues	193	211
Other Key Products \| Creon \| United States
Disaggregation of Revenue
Net revenues	305	287
Other Key Products \| Linzess/Constella
Disaggregation of Revenue
Net revenues	259	240
Other Key Products \| Linzess/Constella \| United States
Disaggregation of Revenue
Net revenues	251	233
Other Key Products \| Linzess/Constella \| International
Disaggregation of Revenue
Net revenues	$ 8	$ 7

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