Licensing, Acquisitions and Other Arrangements (Details) - USD ($) $ in Millions |
3 Months Ended | ||
|---|---|---|---|
Mar. 31, 2023 |
Mar. 31, 2022 |
Feb. 28, 2022 |
|
| Collaborative and license agreements | |||
| Cash outflows related to acquisitions and investments | $ (353) | $ (185) | |
| Acquired IPR&D and milestones | 150 | 145 | |
| Collaborative arrangement | |||
| Collaborative and license agreements | |||
| Research and development milestone expenses | 18 | 15 | |
| Syndesi | Collaborative arrangement | |||
| Collaborative and license agreements | |||
| Acquired IPR&D and milestones | $ 130 | ||
| Syndesi | Collaborative arrangement | Maximum | |||
| Collaborative and license agreements | |||
| Potential payments under agreement certain milestones | $ 870 | ||
| Other Collaboration Arrangements | Collaborative arrangement | |||
| Collaborative and license agreements | |||
| Acquired IPR&D and milestones | $ 132 | ||