v3.23.1
Licensing, Acquisitions and Other Arrangements (Details) - USD ($)
$ in Millions
3 Months Ended
Mar. 31, 2023
Mar. 31, 2022
Feb. 28, 2022
Collaborative and license agreements      
Cash outflows related to acquisitions and investments $ (353) $ (185)  
Acquired IPR&D and milestones 150 145  
Collaborative arrangement      
Collaborative and license agreements      
Research and development milestone expenses 18 15  
Syndesi | Collaborative arrangement      
Collaborative and license agreements      
Acquired IPR&D and milestones   $ 130  
Syndesi | Collaborative arrangement | Maximum      
Collaborative and license agreements      
Potential payments under agreement certain milestones     $ 870
Other Collaboration Arrangements | Collaborative arrangement      
Collaborative and license agreements      
Acquired IPR&D and milestones $ 132