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Goodwill and Intangible Assets (Tables)
 12 Months Ended
Dec. 31, 2021
Goodwill and Intangible Assets Disclosure [Abstract]  
Summary of changes in the carrying amount of goodwill
The following table summarizes the changes in the carrying amount of goodwill:
(in millions)
Balance as of December 31, 2019$15,604 
Additions(a)
17,008 
Foreign currency translation adjustments512 
Balance as of December 31, 202033,124 
Additions(b)
177 
Measurement period adjustments(c)
(564)
Foreign currency translation adjustments and other(358)
Balance as of December 31, 2021$32,379 
(a)Goodwill additions related to the acquisition of Allergan in the second quarter of 2020 and the acquisition of Luminera in the fourth quarter of 2020 (see Note 5).
(b)Goodwill additions related to the acquisition of Soliton in the fourth quarter of 2021 (see Note 5).
(c)Measurement period adjustments recorded in 2021 related to the acquisition of Allergan (see Note 5).
Schedule of definite-lived intangible assets The following table summarizes intangible assets:
20212020
as of December 31 (in millions)Gross
 carrying
 amount		Accumulated
 amortization		Net
 carrying
 amount		Gross
 carrying
 amount		Accumulated
 amortization		Net
 carrying
 amount
Definite-lived intangible assets
Developed product rights$88,945 $(18,463)$70,482 $87,707 $(11,620)$76,087 
License agreements8,487 (3,688)4,799 7,828 (2,916)4,912 
Total definite-lived intangible assets97,432 (22,151)75,281 95,535 (14,536)80,999 
Indefinite-lived research and development670 — 670 1,877 — 1,877 
Total intangible assets, net$98,102 $(22,151)$75,951 $97,412 $(14,536)$82,876 
Schedule of indefinite-lived intangible assets The following table summarizes intangible assets:
20212020
as of December 31 (in millions)Gross
 carrying
 amount		Accumulated
 amortization		Net
 carrying
 amount		Gross
 carrying
 amount		Accumulated
 amortization		Net
 carrying
 amount
Definite-lived intangible assets
Developed product rights$88,945 $(18,463)$70,482 $87,707 $(11,620)$76,087 
License agreements8,487 (3,688)4,799 7,828 (2,916)4,912 
Total definite-lived intangible assets97,432 (22,151)75,281 95,535 (14,536)80,999 
Indefinite-lived research and development670 — 670 1,877 — 1,877 
Total intangible assets, net$98,102 $(22,151)$75,951 $97,412 $(14,536)$82,876 
Schedule of anticipated annual amortization expense The anticipated annual amortization expense for definite-lived intangible assets recorded as of December 31, 2021 is as follows:
(in billions)20222023202420252026
Anticipated annual amortization expense$7.2 $7.5 $8.0 $8.4 $7.9