v3.25.0.1
Segment and Geographic Information - Summary of Reconciliation of Segment Financial Information to Loss from Operations (Detail) - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2024
Dec. 31, 2023
Dec. 31, 2022
Segment Reporting Information [Line Items]      
Income (loss) from operations $ 310,403 $ 119,966 $ (161,201)
Total stock-based compensation expense 691,638 475,903 564,798
Reconciling items      
Segment Reporting Information [Line Items]      
Income (loss) from operations 310,403 119,966 (161,201)
Research and development expenses 342,813 306,560 265,808
General and administrative expenses 375,094 343,126 365,768
Total stock-based compensation expense 691,638 475,903 564,798
Operating Segments      
Segment Reporting Information [Line Items]      
Total contribution $ 1,719,948 $ 1,245,555 $ 1,035,173