INCOME TAXES - Summary of Deferred Tax Assets and Liabilities (Details) - USD ($) $ in Millions	12 Months Ended
Dec. 31, 2025	Dec. 31, 2024
Deferred tax assets:
Net operating loss carryforwards	$ 266	$ 288
Stock-based compensation	83	84
Reserves and accruals not currently deductible	688	685
Excess of tax basis over book basis of intangible assets	776	910
Deductible acquired IPR&D payments	1,293	1,312
Research and other credit carryforwards	353	428
Equity investments	111	237
Liability related to future royalties	270	287
Capitalized R&D expenditures	1,773	2,173
Capital losses	187	590
Other, net	252	213
Total deferred tax assets before valuation allowance	6,052	7,207
Valuation allowance	(676)	(1,217)
Total deferred tax assets	5,376	5,990
Deferred tax liabilities:
Property, plant and equipment	(288)	(276)
Excess of book basis over tax basis of intangible assets	(3,209)	(3,836)
Equity investments	(92)	(81)
Other	(225)	(143)
Total deferred tax liabilities	(3,814)	(4,336)
Net deferred tax assets	1,562	1,654
Valuation allowance increase (decrease)	$ (541)	$ 554

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