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Collaborative arrangements (Details Textual) (Collaborative arrangement with AstraZeneca PLC [Member], USD $)
In Millions, unless otherwise specified |
9 Months Ended |
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Sep. 30, 2012
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| Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] | |
| Percentage of related development costs for the 2012-2014 periods will be funded by partner | 65.00% |
| Ratio of development cost sharing after 2014 | the companies will share costs equally |
| Ratio of profits and losses shared with partner | profits and losses related to the collaboration would be shared equally |
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Other revenues [Member]
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| Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] | |
| Milestone payments received | 50 |