v3.25.4
Goodwill and Other Intangibles - Narrative (Details) - USD ($)
$ in Millions
12 Months Ended
Dec. 31, 2025
Dec. 31, 2024
Dec. 31, 2023
Intangible Assets Excluding Goodwill [Line Items]      
Other intangibles, net $ 26,681 $ 16,370  
Amortization expense for intangible assets 2,800 2,400 $ 2,000
Estimated aggregate amortization expense, 2026 3,800    
Estimated aggregate amortization expense, 2027 3,600    
Estimated aggregate amortization expense, 2028 3,300    
Estimated aggregate amortization expense, 2029 3,000    
Estimated aggregate amortization expense, 2030 2,700    
IPR&D      
Intangible Assets Excluding Goodwill [Line Items]      
IPR&D intangible asset 427 430  
Animal Health      
Intangible Assets Excluding Goodwill [Line Items]      
Other intangibles, net 3,700    
Nemtabrutinib | IPR&D      
Intangible Assets Excluding Goodwill [Line Items]      
IPR&D intangible asset 418    
gefapixant | IPR&D      
Intangible Assets Excluding Goodwill [Line Items]      
IPR&D impairment charges     $ 779
Impairment, Intangible Asset, Indefinite-Lived (Excluding Goodwill), Statement of Income or Comprehensive Income [Extensible Enumeration]     Research and development
Product rights      
Intangible Assets Excluding Goodwill [Line Items]      
Finite-lived intangible assets, net 21,328 10,922  
Product rights | Ohtuvayre      
Intangible Assets Excluding Goodwill [Line Items]      
Finite-lived intangible assets, net 11,800    
Product rights | Winrevair      
Intangible Assets Excluding Goodwill [Line Items]      
Finite-lived intangible assets, net 5,400    
Product rights | Reblozyl      
Intangible Assets Excluding Goodwill [Line Items]      
Finite-lived intangible assets, net 2,500    
Product rights | Animal Health      
Intangible Assets Excluding Goodwill [Line Items]      
Finite-lived intangible assets, net 1,300    
Trade names      
Intangible Assets Excluding Goodwill [Line Items]      
Finite-lived intangible assets, net 1,723 1,927  
Trade names | Animal Health      
Intangible Assets Excluding Goodwill [Line Items]      
Finite-lived intangible assets, net 1,700    
Licensing Agreements | Keytruda Qlex      
Intangible Assets Excluding Goodwill [Line Items]      
Finite-lived intangible assets, net 886    
Licenses and other      
Intangible Assets Excluding Goodwill [Line Items]      
Finite-lived intangible assets, net 3,203 $ 3,091  
Licenses and other | Lynparza      
Intangible Assets Excluding Goodwill [Line Items]      
Finite-lived intangible assets, net 844    
Licenses and other | Lenvima      
Intangible Assets Excluding Goodwill [Line Items]      
Finite-lived intangible assets, net 201    
Licenses and other | Adempas      
Intangible Assets Excluding Goodwill [Line Items]      
Finite-lived intangible assets, net $ 280