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Collaborative Arrangements - Daiicho Sankyo (Details) - USD ($)
$ in Millions
12 Months Ended
Dec. 31, 2025
Dec. 31, 2024
Dec. 31, 2023
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]      
Cost of sales $ 16,382 $ 15,193 $ 16,126
Selling, general and administrative 10,733 10,816 10,504
Research and development 15,789 17,938 30,531
Other current assest 43,516 38,782  
Accrued and other current liabilities 14,468 15,694  
Daiichi Sankyo | Collaborative Arrangement, Transaction with Party to Collaborative Arrangement      
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]      
Cost of sales 66 0 0
Selling, general and administrative 28 26 3
Research and development 524 351 $ 5,549
Other current assest 15 8  
Accrued and other current liabilities $ 113 $ 817