| Segments of business and geographic areas |
Segments of business and geographic areas The Company is organized into two business segments: Innovative Medicine and MedTech. The Company’s chief operating decision maker (CODM) is the Chief Executive Officer (Principal Executive Officer). For the Innovative Medicine and MedTech segments, the CODM uses segment income before tax to allocate resources (including employees, financial, and capital resources) for each segment predominantly in the annual forecasting process. The CODM considers planning-to-actual variances on a quarterly basis to assess performance and make decisions about allocating resources to the segments. Sales by segment of business | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | Fiscal First Quarter Ended | | | | (Dollars in Millions) | | March 29, 2026 | | March 30, 2025 | | Percent Change | | | | | | | | | | | | | | | | | | | | | INNOVATIVE MEDICINE | | | | | | | | | | | | | | Oncology | | | | | | | | | | | | | U.S. | | $3,615 | | 3,013 | | 20.0 | % | | | | | | | International | | 3,358 | | 2,664 | | 26.0 | | | | | | | | Worldwide | | 6,973 | | 5,678 | | 22.8 | | | | | | | | DARZALEX | | | | | | | | | | | | | U.S. | | 2,208 | | 1,829 | | 20.7 | | | | | | | | International | | 1,756 | | 1,409 | | 24.7 | | | | | | | | Worldwide | | 3,964 | | 3,237 | | 22.5 | | | | | | | | CARVYKTI | | | | | | | | | | | | | U.S. | | 433 | | 318 | | 36.2 | | | | | | | International | | 164 | | 51 | | * | | | | | | | Worldwide | | 597 | | 369 | | 62.1 | | | | | | | | TECVAYLI | | | | | | | | | | | | | U.S. | | 127 | | 105 | | 20.6 | | | | | | | | International | | 74 | | 46 | | 63.1 | | | | | | | Worldwide | | 202 | | 151 | | 33.5 | | | | | | | | | TALVEY | | | | | | | | | | | | | U.S. | | 101 | | 68 | | 48.5 | | | | | | | | International | | 51 | | 18 | | * | | | | | | | Worldwide | | 152 | | 86 | | 76.7 | | | | | | | | | RYBREVANT/ LAZCLUZE | | | | | | | | | | | | | U.S. | | 175 | | 113 | | 55.1 | | | | | | | International | | 82 | | 28 | | * | | | | | | | Worldwide | | 257 | | 141 | | 82.7 | | | | | | | ERLEADA | | | | | | | | | | | | | U.S. | | 342 | | 292 | | 17.3 | | | | | | | | International | | 607 | | 479 | | 26.7 | | | | | | | | Worldwide | | 949 | | 771 | | 23.1 | | | | | | | | IMBRUVICA | | | | | | | | | | | | | U.S. | | 143 | | 235 | | (39.1) | | | | | | | | International | | 517 | | 474 | | 9.1 | | | | | | | | Worldwide | | 660 | | 709 | | (6.9) | | | | | | | |
| | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | Fiscal First Quarter Ended | | | | (Dollars in Millions) | | March 29, 2026 | | March 30, 2025 | | Percent Change | | | | | | | OTHER ONCOLOGY(1) | | | | | | | | | | | | | U.S. | | 85 | | 54 | | 58.8 | | | | | | | | International | | 106 | | 160 | | (33.9) | | | | | | | | Worldwide | | 192 | | 214 | | (10.6) | | | | | | | | | Immunology | | | | | | | | | | | | | U.S. | | 1,855 | | 2,196 | | (15.5) | | | | | | | | International | | 1,524 | | 1,510 | | 0.9 | | | | | | | | Worldwide | | 3,380 | | 3,707 | | (8.8) | | | | | | | | | TREMFYA | | | | | | | | | | | | | U.S. | | 1,042 | | 599 | | 73.9 | | | | | | | | International | | 566 | | 356 | | 58.9 | | | | | | | | Worldwide | | 1,608 | | 956 | | 68.3 | | | | | | | | SIMPONI / SIMPONI ARIA | | | | | | | | | | | | | U.S. | | 269 | | 292 | | (7.8) | | | | | | | | International | | 378 | | 366 | | 3.0 | | | | | | | | Worldwide | | 647 | | 659 | | (1.7) | | | | | | | | REMICADE | | | | | | | | | | | | | U.S. | | 269 | | 314 | | (14.4) | | | | | | | | U.S. Exports | | 18 | | 10 | | 78.6 | | | | | | | | International | | 136 | | 143 | | (4.8) | | | | | | | | Worldwide | | 422 | | 467 | | (9.5) | | | | | | | | STELARA | | | | | | | | | | | | | U.S. | | 220 | | 981 | | (77.6) | | | | | | | | International | | 435 | | 644 | | (32.4) | | | | | | | | Worldwide | | 656 | | 1,625 | | (59.7) | | | | | | | | OTHER IMMUNOLOGY | | | | | | | | | | | | | U.S. | | 38 | | 1 | | * | | | | | | | International | | 9 | | 0 | | * | | | | | | | Worldwide | | 46 | | 1 | | * | | | | | | | | Neuroscience | | | | | | | | | | | | | U.S. | | 1,494 | | 968 | | 54.3 | | | | | | | | International | | 681 | | 679 | | 0.3 | | | | | | | | Worldwide | | 2,175 | | 1,647 | | 32.0 | | | | | | | | SPRAVATO | | | | | | | | | | | | | U.S. | | 406 | | 276 | | 47.0 | | | | | | | | International | | 61 | | 43 | | 42.4 | | | | | | | | Worldwide | | 468 | | 320 | | 46.4 | | | | | | | | CAPLYTA(2) | | | | | | | | | | | | | U.S. | | 270 | | — | | * | | | | | | | International | | — | | — | | — | | | | | | | | Worldwide | | 270 | | — | | * | | | | | | | | | | | | | | | | | | | |
| | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | Fiscal First Quarter Ended | | | | (Dollars in Millions) | | March 29, 2026 | | March 30, 2025 | | Percent Change | | | | | | | INVEGA SUSTENNA / XEPLION / INVEGA TRINZA / TREVICTA | | | | | | | | | | | | | U.S. | | 758 | | 625 | | 21.2 | | | | | | | | International | | 280 | | 277 | | 1.1 | | | | | | | | Worldwide | | 1,038 | | 903 | | 15.0 | | | | | | | | CONCERTA / methylphenidate | | | | | | | | | | | | | U.S. | | 22 | | 38 | | (43.4) | | | | | | | | International | | 115 | | 110 | | 4.3 | | | | | | | | Worldwide | | 136 | | 148 | | (8.0) | | | | | | | | | OTHER NEUROSCIENCE | | | | | | | | | | | | | U.S. | | 38 | | 28 | | 32.6 | | | | | | | | International | | 224 | | 248 | | (9.7) | | | | | | | | Worldwide | | 262 | | 277 | | (5.4) | | | | | | | | | Pulmonary Hypertension (PH) | | | | | | | | | | | | | U.S. | | 831 | | 744 | | 11.7 | | | | | | | | International | | 304 | | 281 | | 8.2 | | | | | | | | Worldwide | | 1,135 | | 1,025 | | 10.7 | | | | | | | | UPTRAVI | | | | | | | | | | | | | | U.S. | | 385 | | 365 | | 5.4 | | | | | | | | | International | | 98 | | 86 | | 14.3 | | | | | | | | | Worldwide | | 483 | | 451 | | 7.1 | | | | | | | | | OPSUMIT/OPSYNVI | | | | | | | | | | | | | | U.S. | | 433 | | 363 | | 19.3 | | | | | | | | | International | | 172 | | 159 | | 8.7 | | | | | | | | | Worldwide | | 606 | | 522 | | 16.1 | | | | | | | | | OTHER PULMONARY HYPERTENSION | | | | | | | | | | | | | U.S. | | 12 | | 15 | | (21.1) | | | | | | | | | International | | 34 | | 37 | | (8.3) | | | | | | | | | Worldwide | | 46 | | 52 | | (12.1) | | | | | | | | | Infectious Diseases (ID) | | | | | | | | | | | | | U.S. | | 342 | | 315 | | 8.6 | | | | | | | | International | | 547 | | 487 | | 12.2 | | | | | | | | Worldwide | | 889 | | 802 | | 10.8 | | | | | | | | EDURANT / rilpivirine | | | | | | | | | | | | | U.S. | | 7 | | 8 | | (13.1) | | | | | | | | International | | 402 | | 350 | | 14.8 | | | | | | | | Worldwide | | 409 | | 358 | | 14.1 | | | | | | | | PREZISTA / PREZCOBIX / REZOLSTA / SYMTUZA | | | | | | | | | | | | | U.S. | | 334 | | 305 | | 9.5 | | | | | | | | International | | 109 | | 98 | | 11.2 | | | | | | | | Worldwide | | 443 | | 403 | | 10.0 | | | | | | | | | | | | | | | | | | | | |
| | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | Fiscal First Quarter Ended | | | | (Dollars in Millions) | | March 29, 2026 | | March 30, 2025 | | Percent Change | | | | | | | | OTHER INFECTIOUS DISEASES | | | | | | | | | | | | | U.S. | | 1 | | 2 | | (56.9) | | | | | | | | International | | 36 | | 39 | | (8.3) | | | | | | | | Worldwide | | 37 | | 41 | | (10.4) | | | | | | | | | Cardiovascular / Metabolism / Other (CVM) | | | | | | | | | | | | | | U.S. | | 734 | | 855 | | (14.2) | | | | | | | | | International | | 142 | | 158 | | (10.4) | | | | | | | | | Worldwide | | 876 | | 1,013 | | (13.6) | | | | | | | | XARELTO | | | | | | | | | | | | | | U.S. | | 642 | | 690 | | (7.0) | | | | | | | | | International | | — | | — | | — | | | | | | | | | Worldwide | | 642 | | 690 | | (7.0) | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | OTHER | | | | | | | | | | | | | | U.S. | | 91 | | 165 | | (44.5) | | | | | | | | | International | | 142 | | 158 | | (10.4) | | | | | | | | | Worldwide | | 233 | | 323 | | (27.8) | | | | | | | | | Total PH, ID, CVM | | | | | | | | | | | | | | U.S. | | 1,907 | | 1,914 | | (0.4) | | | | | | | | | International | | 993 | | 926 | | 7.1 | | | | | | | | | Worldwide | | 2,899 | | 2,840 | | 2.1 | | | | | | | | | | | | | | | | | | | | | | TOTAL INNOVATIVE MEDICINE | | | | | | | | | | | | | | U.S. | | 8,871 | | 8,092 | | 9.6 | | | | | | | | | International | | 6,555 | | 5,781 | | 13.4 | | | | | | | | | Worldwide | | 15,426 | | 13,873 | | 11.2 | | | | | | | | | | | | | | | | | | | | | | MEDTECH | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | Cardiovascular | | | | | | | | | | | | | | U.S. | | 1,399 | | 1,261 | | 10.9 | | | | | | | | | International | | 978 | | 842 | | 16.1 | | | | | | | | | Worldwide | | 2,377 | | 2,103 | | 13.0 | | | | | | | | ELECTROPHYSIOLOGY | | | | | | | | | | | | | | U.S. | | 736 | | 684 | | 7.6 | | | | | | | | | International | | 753 | | 638 | | 18.0 | | | | | | | | | Worldwide | | 1,489 | | 1,323 | | 12.6 | | | | | | | | ABIOMED | | | | | | | | | | | | | | U.S. | | 389 | | 339 | | 14.5 | | | | | | | | | International | | 100 | | 81 | | 23.5 | | | | | | | | | Worldwide | | 488 | | 420 | | 16.3 | | | | | | | | | SHOCKWAVE | | | | | | | | | | | | | | U.S. | | 242 | | 206 | | 17.8 | | | | | | | | | International | | 63 | | 52 | | 21.3 | | | | | | | | | Worldwide | | 305 | | 258 | | 18.5 | | | | | | | | | | | | | | | | | | | | |
| | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | Fiscal First Quarter Ended | | | | (Dollars in Millions) | | March 29, 2026 | | March 30, 2025 | | Percent Change | | | | | | | | OTHER CARDIOVASCULAR | | | | | | | | | | | | | | U.S. | | 32 | | 32 | | 0.7 | | | | | | | | | International | | 62 | | 72 | | (13.4) | | | | | | | | | Worldwide | | 94 | | 103 | | (9.1) | | | | | | | | | Surgery | | | | | | | | | | | | | | U.S. | | 1,046 | | 1,002 | | 4.4 | | | | | | | | | International | | 1,465 | | 1,394 | | 5.1 | | | | | | | | | Worldwide | | 2,511 | | 2,396 | | 4.8 | | | | | | | | ADVANCED | | | | | | | | | | | | | | U.S. | | 477 | | 457 | | 4.2 | | | | | | | | | International | | 646 | | 616 | | 4.9 | | | | | | | | | Worldwide | | 1,123 | | 1,073 | | 4.6 | | | | | | | | GENERAL | | | | | | | | | | | | | | U.S. | | 569 | | 544 | | 4.5 | | | | | | | | | International | | 819 | | 778 | | 5.2 | | | | | | | | | Worldwide | | 1,388 | | 1,323 | | 4.9 | | | | | | | | | Vision | | | | | | | | | | | | | | U.S. | | 579 | | 566 | | 2.4 | | | | | | | | | International | | 785 | | 713 | | 10.1 | | | | | | | | | Worldwide | | 1,365 | | 1,279 | | 6.7 | | | | | | | | CONTACT LENSES / OTHER | | | | | | | | | | | | | | U.S. | | 468 | | 452 | | 3.7 | | | | | | | | | International | | 501 | | 467 | | 7.2 | | | | | | | | | Worldwide | | 969 | | 919 | | 5.5 | | | | | | | | SURGICAL | | | | | | | | | | | | | | U.S. | | 111 | | 114 | | (2.9) | | | | | | | | | International | | 285 | | 246 | | 15.6 | | | | | | | | | Worldwide | | 396 | | 361 | | 9.7 | | | | | | | | | Orthopaedics* | | | | | | | | | | | | | | U.S. | | 1,435 | | 1,384 | | 3.7 | | | | | | | | | International | | 948 | | 857 | | 10.6 | | | | | | | | | Worldwide | | 2,383 | | 2,241 | | 6.3 | | | | | | | | HIPS | | | | | | | | | | | | | | U.S. | | 277 | | 263 | | 5.2 | | | | | | | | | International | | 159 | | 146 | | 8.9 | | | | | | | | | Worldwide | | 436 | | 409 | | 6.5 | | | | | | | | KNEES | | | | | | | | | | | | | | U.S. | | 239 | | 231 | | 3.3 | | | | | | | | | International | | 181 | | 158 | | 14.6 | | | | | | | | | Worldwide | | 420 | | 389 | | 7.9 | | | | | | | |
| | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | Fiscal First Quarter Ended | | | | (Dollars in Millions) | | March 29, 2026 | | March 30, 2025 | | Percent Change | | | | | | | TRAUMA | | | | | | | | | | | | | | U.S. | | 532 | | 502 | | 6.1 | | | | | | | | | International | | 301 | | 270 | | 11.4 | | | | | | | | | Worldwide | | 833 | | 772 | | 8.0 | | | | | | | | SPINE, SPORTS & OTHER | | | | | | | | | | | | | | U.S. | | 387 | | 388 | | (0.1) | | | | | | | | | International | | 307 | | 283 | | 8.4 | | | | | | | | | Worldwide | | 694 | | 671 | | 3.5 | | | | | | | | | | | | | | | | | | | | | | TOTAL MEDTECH | | | | | | | | | | | | | | U.S. | | 4,459 | | 4,213 | | 5.9 | | | | | | | | | International | | 4,177 | | 3,807 | | 9.7 | | | | | | | | | Worldwide | | 8,636 | | 8,020 | | 7.7 | | | | | | | | | | | | | | | | | | | | | | WORLDWIDE | | | | | | | | | | | | | | U.S. | | 13,330 | | 12,305 | | 8.3 | | | | | | | | | International | | 10,732 | | 9,588 | | 11.9 | | | | | | | | | Worldwide | | $24,062 | | 21,893 | | 9.9 | % | | | | | | |
* Percentage greater than 100% or not meaningful (1) Includes the sales of ZYTIGA which were previously disclosed separately (2) Acquired with Intra-Cellular Therapies on April 2, 2025
Adjustments to revenue recognized as a result of changes in estimates for the Company's most significant U.S. rebates and discounts liability balances for products shipped in previous periods were approximately 4.7% and 4.6% of U.S. Innovative Medicine revenue during the fiscal first quarter of 2026 and 2025, respectively. *In October 2025, the Company announced its intention to separate its Orthopaedics business. The Company continues to explore multiple paths to effect the planned separation with a targeted completion within 18 to 24 months after the initial announcement. Segment income before tax | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | Fiscal First Quarter Ended | | | | (Dollars in Millions) | | March 29, 2026 | | March 30, 2025 | | | | | | | | | | | | | | Innovative Medicine(1) | MedTech(2) | Total | | Innovative Medicine(1) | MedTech(2) | Total | | | | | | | | | | | | | Sales to customers | | $15,426 | 8,636 | | | 13,873 | 8,020 | | | | | | | | | | | | | | Cost of products sold | | 4,390 | 3,701 | | | 4,020 | 3,326 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | Selling, marketing and administrative | | 2,918 | 2,906 | | | 2,261 | 2,656 | | | | | | | | | | | | | | Research and development expense | | 2,813 | 714 | | | 2,548 | 677 | | | | | | | | | | | | | Other segment items (3) | | (12) | 76 | | | (166) | (60) | | | | | | | | | | | | | | Segment income before tax | | $5,317 | 1,239 | 6,556 | | 5,210 | 1,421 | 6,631 | | | | | | | | | | | | (Income)/Expense not allocated to segments (4) | | | | 566 | | | | (7,000) | | | | | | | | | | | | | Earnings before provision for taxes on income | | | | $5,990 | | | | $13,631 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
(1) Innovative Medicine includes: •Intangible amortization expense of $0.8 billion and $0.6 billion in the fiscal first quarters of 2026 and 2025, respectively. (2) MedTech includes: •Intangible amortization expense of $0.5 billion in both the fiscal first quarters of 2026 and 2025. •Orthopaedics Separation related charge of $0.1 billion in the fiscal first quarter of 2026. •Acquisition and integration related expense of $0.1 billion in the fiscal first quarter of 2025, primarily related to Shockwave. (3) Other segment items for each reportable segment include other income and expense (gains and losses on divestitures and gains and losses on sale of assets), restructuring activities and impairment charges related to in-process research and development (4) Amounts not allocated to segments include interest (income)/expense and general corporate (income)/expense. The fiscal first quarter of 2026 includes charges for talc matters of $0.3 billion. The fiscal first quarter of 2025 includes approximately $7.0 billion related to the talc reserve reversal. | | | | | | | | | | | | | | | | | Identifiable Assets | | (Dollars in Millions) | | March 29, 2026 | | December 28, 2025 | | Innovative Medicine | | $78,118 | | 78,057 | | MedTech | | 86,179 | | 86,482 | | Total | | 164,297 | | 164,539 | General corporate (1) | | 36,597 | | 34,671 | | Worldwide total | | $200,894 | | 199,210 | (1)General corporate includes cash, cash equivalents, marketable securities and other corporate assets. | | | | | | | | | | | | | | | | | | | | | | | | | | | | | Additions to Property, Plant & Equipment | | Depreciation and Amortization | | | Fiscal Three Months Ended | | (Dollars in Millions) | | March 29, 2026 | | March 30, 2025 | | March 29, 2026 | | March 30, 2025 | | Innovative Medicine | | $508 | | 276 | | $1,036 | | 884 | | MedTech | | 509 | | 480 | | 903 | | 836 | | Segments total | | 1,017 | | 756 | | 1,939 | | 1,720 | | General corporate | | 32 | | 39 | | 65 | | 52 | | Worldwide total | | $1,049 | | 795 | | $2,004 | | 1,772 |
Sales by geographic area | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | Fiscal First Quarter Ended | | | | (Dollars in Millions) | | March 29, 2026 | | March 30, 2025 | | Percent Change | | | | | | | | United States | | $13,330 | | 12,305 | | 8.3 | % | | | | | | | | Europe | | 5,848 | | 5,110 | | 14.5 | | | | | | | | | Western Hemisphere, excluding U.S. | | 1,293 | | 1,167 | | 10.8 | | | | | | | | | Asia-Pacific, Africa | | 3,591 | | 3,311 | | 8.5 | | | | | | | | | Total | | $24,062 | | 21,893 | | 9.9 | % | | | | | | |
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