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Restructuring Plans - 2017 to 2020 Restructuring Plans (Details) - Streamline of Operations and Improve Efficiencies - USD ($) $ in Millions	12 Months Ended		24 Months Ended
	Dec. 31, 2020	Dec. 31, 2019	Dec. 31, 2020	Dec. 31, 2021	Dec. 31, 2018
Restructuring Plans
Employee related severance and other charges	$ 36	$ 66	$ 102
Accrued balance				$ 24	$ 70
Cost of products sold
Restructuring Plans
Restructuring charges recorded in 2021			22
Research and development
Restructuring Plans
Restructuring charges recorded in 2021			30
Selling, general and administrative expense
Restructuring Plans
Restructuring charges recorded in 2021			$ 50